2021
Early but not late convalescent plasma is associated with better survival in moderate-to-severe COVID-19
Briggs N, Gormally MV, Li F, Browning SL, Treggiari MM, Morrison A, Laurent-Rolle M, Deng Y, Hendrickson JE, Tormey CA, Desruisseaux MS. Early but not late convalescent plasma is associated with better survival in moderate-to-severe COVID-19. PLOS ONE 2021, 16: e0254453. PMID: 34320004, PMCID: PMC8318280, DOI: 10.1371/journal.pone.0254453.Peer-Reviewed Original ResearchConceptsCOVID-19 convalescent plasmaSevere COVID-19Convalescent plasmaPlasma recipientsHospital mortalityUnexposed cohortCCP administrationSevere COVID-19 infectionPropensity score-matched analysisCOVID-19Limited therapeutic optionsCOVID-19 infectionCoronavirus disease 2019CCP recipientsHospital stayPrimary endpointSecondary endpointsHospital daysHospital dischargeEarly administrationComplete followMechanical ventilationTherapeutic optionsClinical differencesSevere disease
2018
Using System Inflammatory Response Syndrome as an Easy-to-Implement, Sustainable, and Automated Tool for All-Cause Deterioration Among Medical Inpatients
Fogerty RL, Sussman LS, Kenyon K, Li F, Sukumar N, Kliger AS, Acker K, Sankey C. Using System Inflammatory Response Syndrome as an Easy-to-Implement, Sustainable, and Automated Tool for All-Cause Deterioration Among Medical Inpatients. Journal Of Patient Safety 2018, Publish Ahead of Print: &na;. PMID: 29369071, DOI: 10.1097/pts.0000000000000463.Peer-Reviewed Original ResearchConceptsDefinition of sepsisClinical deteriorationMedical inpatientsAdult inpatientsSystemic inflammatory response syndrome criteriaElectronic health record toolsInflammatory response syndromeAcademic medical centerSyndrome criteriaResponse syndromeClinical benefitMedical CenterHigh riskMinimal additional resourcesInpatientsSIRSSepsisPatientsIntervention toolSpectrum disorderDeteriorationAdmissionSyndrome