2020
Medial Nucleus Accumbens Projections to the Ventral Tegmental Area Control Food Consumption
Bond CW, Trinko R, Foscue E, Furman K, Groman SM, Taylor JR, DiLeone RJ. Medial Nucleus Accumbens Projections to the Ventral Tegmental Area Control Food Consumption. Journal Of Neuroscience 2020, 40: 4727-4738. PMID: 32354856, PMCID: PMC7294796, DOI: 10.1523/jneurosci.3054-18.2020.Peer-Reviewed Original ResearchConceptsControl food intakeNAc projectionsFood intakeAccumbens projectionsLateral hypothalamusMesolimbic circuitsFood consumptionNucleus accumbens projectionsFood-seeking behaviorNAC controlVTA pathwayInhibitory projectionsMale miceNAc shellOptogenetic activationFiber photometryOptogenetic inhibitionPermissive rolePharmacological studiesDrug rewardVTAConsummatory behaviorIntakeAdaptive inhibitionNeural activity
2012
Characterization of a semi-rapid method for assessing delay discounting in rodents
Foscue E, Wood K, Schramm-Sapyta N. Characterization of a semi-rapid method for assessing delay discounting in rodents. Pharmacology Biochemistry And Behavior 2012, 101: 187-192. PMID: 22266769, PMCID: PMC3288622, DOI: 10.1016/j.pbb.2012.01.006.Peer-Reviewed Original ResearchConceptsImportant disease processesChronic treatmentRodent modelsPsychiatric disordersDisease processDaily sessionsStable response patternsDrug addictionUnderlying mechanismSession learningOperant responseFuture studiesResponse patternsStable baselineExtended trainingCompulsive gamblingSubsequent daily sessionsObesityBaselineMonthsCocaine