2017
HIV/HCV coinfection and the risk of cardiovascular disease: A meta‐analysis
Osibogun O, Ogunmoroti O, Michos E, Spatz E, Olubajo B, Nasir K, Madhivanan P, Maziak W. HIV/HCV coinfection and the risk of cardiovascular disease: A meta‐analysis. Journal Of Viral Hepatitis 2017, 24: 998-1004. PMID: 28502092, DOI: 10.1111/jvh.12725.Peer-Reviewed Original ResearchMeSH KeywordsCardiovascular DiseasesCoinfectionFemaleHepacivirusHepatitis CHIVHIV InfectionsHumansMaleProportional Hazards ModelsRiskSocioeconomic FactorsConceptsHIV/HCV coinfectionHCV coinfectionHazard ratioCardiovascular diseaseHIV monoinfectionCVD riskHepatitis C virus coinfectionTraditional CVD risk factorsC virus coinfectionImproved antiretroviral therapyAdjusted hazard ratioCVD risk factorsRisk reduction therapyCongestive heart failureCoronary artery diseaseHuman immunodeficiency virusIncreased inflammatory responseRandom-effects modelWeb of ScienceHCV individualsAntiretroviral therapyCohort studyCVD outcomesArtery diseaseHeart failure
2015
Comparative Effectiveness of CRT-D Versus Defibrillator Alone in HF Patients With Moderate-to-Severe Chronic Kidney Disease
Friedman DJ, Singh JP, Curtis JP, Tang WHW, Bao H, Spatz ES, Hernandez AF, Patel UD, Al-Khatib SM. Comparative Effectiveness of CRT-D Versus Defibrillator Alone in HF Patients With Moderate-to-Severe Chronic Kidney Disease. Journal Of The American College Of Cardiology 2015, 66: 2618-2629. PMID: 26670062, DOI: 10.1016/j.jacc.2015.09.097.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCardiac Resynchronization TherapyComorbidityComparative Effectiveness ResearchDefibrillators, ImplantableElectric CountershockFemaleGlomerular Filtration RateHeart FailureHospitalizationHumansMaleMedicareProportional Hazards ModelsRenal Insufficiency, ChronicSeverity of Illness IndexSurvival AnalysisTreatment OutcomeUnited StatesConceptsSevere chronic kidney diseaseChronic kidney diseaseCardiac resynchronization therapyCRT-eligible patientsHF hospitalizationKidney diseaseNational Cardiovascular Data Registry ICD RegistryUse of CRTComparative effectivenessInverse probability-weighted analysisReal-world comparative effectivenessEnd-stage renal diseaseCox proportional hazards modelCRT-D useHeart failure hospitalizationAcceptable complication rateDevice-related complicationsProportional hazards modelFine-Gray modelCKD classCKD stageFailure hospitalizationHF patientsPrimary endpointSecondary endpointsCardiac Resynchronization Therapy in Women Versus Men
Zusterzeel R, Spatz ES, Curtis JP, Sanders WE, Selzman KA, Piña IL, Bao H, Ponirakis A, Varosy PD, Masoudi FA, Caños DA, Strauss DG. Cardiac Resynchronization Therapy in Women Versus Men. Circulation Cardiovascular Quality And Outcomes 2015, 8: s4-s11. PMID: 25714821, DOI: 10.1161/circoutcomes.114.001548.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBundle-Branch BlockCardiac Resynchronization TherapyCardiac Resynchronization Therapy DevicesDefibrillators, ImplantableElectric CountershockFemaleHealth Status DisparitiesHeart Conduction SystemHeart FailureHumansKaplan-Meier EstimateMalePropensity ScoreProportional Hazards ModelsRegistriesRisk FactorsSex FactorsStroke VolumeTreatment OutcomeUnited StatesVentricular Function, LeftConceptsLeft bundle branch blockQRS durationImplantable cardioverter defibrillatorPatient sexDeath riskCardioverter defibrillatorBetter survivalMortality differencesNew York Heart Association class IIILeft ventricular ejection fractionWomen Versus MenCardiac resynchronization therapyVentricular ejection fractionRelative death riskBenefit of CRTLonger QRS durationShorter QRS durationBundle branch blockLower mortality riskEjection fractionHeart failureResynchronization therapyCardiac resynchronizationBranch blockMortality risk
2014
Sex-Specific Mortality Risk by QRS Morphology and Duration in Patients Receiving CRT Results From the NCDR
Zusterzeel R, Curtis JP, Caños DA, Sanders WE, Selzman KA, Piña IL, Spatz ES, Bao H, Ponirakis A, Varosy PD, Masoudi FA, Strauss DG. Sex-Specific Mortality Risk by QRS Morphology and Duration in Patients Receiving CRT Results From the NCDR. Journal Of The American College Of Cardiology 2014, 64: 887-894. PMID: 25169173, DOI: 10.1016/j.jacc.2014.06.1162.Peer-Reviewed Original ResearchConceptsLeft bundle branch blockNational Cardiovascular Data RegistryLonger QRS durationQRS durationQRS morphologyHazard ratioMortality riskBetter survivalCardiac resynchronization therapy defibrillator implantationImplantable Cardioverter-Defibrillator RegistrySex-specific mortality risksCRT-D implantationCRT-D patientsBundle branch blockLower mortality riskSex differencesComparator groupBranch blockData registryBetter outcomesPatientsLower mortalitySurvival curvesMortalityWomen