2022
Quantitative Echocardiographic Assessment and Optimal Criteria for Early Intervention in Asymptomatic Tricuspid Regurgitation
Akintoye E, Wang T, Nakhla M, Ali A, Fava A, Akyuz K, Popovic Z, Pettersson G, Gillinov A, Xu B, Griffin B, Desai M. Quantitative Echocardiographic Assessment and Optimal Criteria for Early Intervention in Asymptomatic Tricuspid Regurgitation. JACC Cardiovascular Imaging 2022, 16: 13-24. PMID: 36274042, DOI: 10.1016/j.jcmg.2022.08.004.Peer-Reviewed Original ResearchConceptsTricuspid regurgitationMedian survival timeRisk factorsAsymptomatic patientsEchocardiographic parametersSurvival timeEarly interventionOptimal timingRight heart parametersSymptomatic tricuspid regurgitationSignificant tricuspid regurgitationFree wall strainHigh operative mortalitySex-matched cohortQuantitative echocardiographic assessmentKey prognostic markersCause mortalityOperative mortalityTR patientsEchocardiographic assessmentLate presentationPoor outcomePrognostic utilityPrognostic valuePrognostic markerTrends and Outcomes of Patients With Amyloid Cardiomyopathy Listed for Heart Transplantation
Akintoye E, Salih M, Aje K, Alvarez P, Sellke F, Briasoulis A, Dorbala S. Trends and Outcomes of Patients With Amyloid Cardiomyopathy Listed for Heart Transplantation. Canadian Journal Of Cardiology 2022, 38: 1263-1270. PMID: 35525397, DOI: 10.1016/j.cjca.2022.04.023.Peer-Reviewed Original ResearchConceptsHeart transplantGraft survivalAmyloid cardiomyopathyWaitlist mortalityHeart transplantationRisk factorsSingle-organ heart transplantsStudy periodHeart transplant waitlistUnderwent heart transplantWorse graft survivalGraft survival ratesOutcomes of patientsPropensity-matched cohortOrgan Sharing databaseHigher waitlist mortalityNumber of patientsNumber of transplantsAmyloid recurrenceAdult patientsGraft failureRenal failureIndependent predictorsSharing databaseUnited NetworkWait List And Transplant Outcomes Of Diabetic Patients With Listed For Heart Transplantation: A Propensity-matched Analysis
Akintoye E, Alvarez P, Salih M, Briasoulis A. Wait List And Transplant Outcomes Of Diabetic Patients With Listed For Heart Transplantation: A Propensity-matched Analysis. Journal Of Cardiac Failure 2022, 28: s64. DOI: 10.1016/j.cardfail.2022.03.163.Peer-Reviewed Original ResearchDiabetic patientsWaitlist mortalityHeart transplantPost-transplant graft survivalEnd-stage heart failurePropensity-matched cohortHeart failure patientsGraft survivalAdult patientsFailure patientsGraft failureHeart failureUnited NetworkRisk factorsOrgan SharingPatientsStudy periodTransplantMortalityFailureCohortWaitlistOutcomes of diabetic patients with end‐stage heart failure listed for heart transplantation: A propensity‐matched analysis
Akintoye E, Alvarez P, Salih M, Sellke F, Briasoulis A. Outcomes of diabetic patients with end‐stage heart failure listed for heart transplantation: A propensity‐matched analysis. Clinical Transplantation 2022, 36: e14590. PMID: 35018661, DOI: 10.1111/ctr.14590.Peer-Reviewed Original ResearchConceptsDiabetic patientsWaitlist mortalityHeart transplantPost-transplant graft survivalEnd-stage heart failurePropensity-matched cohortHeart failure patientsGraft survivalAdult patientsFailure patientsGraft failureHeart failureUnited NetworkRisk factorsOrgan SharingPatientsStudy periodTransplantMortalityFailureCohortWaitlist
2021
Short and long term outcomes of cardiac amyloidosis patients listed for heart transplantation in the united states: a propensity-matched analysis
Akintoye E, Alvarez P, Briasoulis A. Short and long term outcomes of cardiac amyloidosis patients listed for heart transplantation in the united states: a propensity-matched analysis. European Heart Journal 2021, 42: ehab724.0965. DOI: 10.1093/eurheartj/ehab724.0965.Peer-Reviewed Original ResearchPost-transplant graft survivalGraft survivalGraft survival ratesPropensity-matched analysisCA patientsHigher waitlist mortalityHeart transplantationCardiac amyloidosis patientsWaitlist mortalityRestrictive cardiomyopathyRisk factorsDonor heartsAmyloidosis patientsSurvival rateStudy periodComparable graft survivalPoor graft survivalPropensity-matched cohortOrgan Sharing databaseSingle-center experienceCohort of patientsPredictors of survivalLong-term outcomesSignificant risk factorsAmyloid recurrenceOutcomes of diabetic patients with end-stage heart failure listed for heart transplantation: a propensity-matched analysis
Akintoye E, Alvarez P, Briasoulis A. Outcomes of diabetic patients with end-stage heart failure listed for heart transplantation: a propensity-matched analysis. European Heart Journal 2021, 42: ehab724.0967. DOI: 10.1093/eurheartj/ehab724.0967.Peer-Reviewed Original ResearchHeart transplantWaitlist mortalityPost-transplant graft survivalEnd-stage heart failureOutcomes of patientsPropensity-matched cohortHeart failure patientsGraft survivalAdult patientsFailure patientsGraft failureDiabetic patientsHeart failureDiabetic cohortPoor outcomeUnited NetworkRisk factorsOrgan SharingPatientsTransplantStudy periodCohortMortalityOutcomesRisk
2019
Trends and Outcomes of Infective Endocarditis in Adults With Tetralogy of Fallot: A Review of the National Inpatient Sample Database
Egbe A, Vallabhajosyula S, Akintoye E, Connolly H. Trends and Outcomes of Infective Endocarditis in Adults With Tetralogy of Fallot: A Review of the National Inpatient Sample Database. Canadian Journal Of Cardiology 2019, 35: 721-726. PMID: 31151707, DOI: 10.1016/j.cjca.2019.02.006.Peer-Reviewed Original ResearchConceptsHealth care resource utilizationTetralogy of FallotProsthetic valve implantationNational Inpatient SampleCongenital heart diseaseHospital mortalityValve implantationInfective endocarditisHeart diseaseRisk factorsTOF patientsInflation-adjusted hospitalization costsNational Inpatient Sample databaseCyanotic congenital heart diseaseIncidence of endocarditisLength of stayPacemaker/defibrillatorLow socioeconomic classPopulation-based riskHospital dischargeSecondary outcomesPrimary outcomeHospitalization costsBlack raceInpatient Sample
2018
Intra-thoracic Impedance and the Onset of Atrial and Ventricular Tachyarrhythmias: A Meta-analysis
Abubakar H, Osman M, Akintoye E, Subahi A, Osman K, Abidov A. Intra-thoracic Impedance and the Onset of Atrial and Ventricular Tachyarrhythmias: A Meta-analysis. International Journal Of Cardiology 2018, 258: 144-150. PMID: 29544921, DOI: 10.1016/j.ijcard.2017.12.092.Peer-Reviewed Original ResearchConceptsAT/AFVT/VFOptiVol fluid indexOdds ratioImplantable cardioverter-defibrillator devicesSignificant risk factorsFluid index threshold crossingCardioverter-defibrillator devicesLarger pooled populationFluid overloadVentricular tachyarrhythmiasArrhythmic eventsRisk factorsFluid indexMeta-AnalysisPatientsICD devicesPooled populationEffect estimatesConfidence intervalsOnsetPooled samplesVFAssociationAF
2017
Outcomes of cardiac pacing in adult patients after a Fontan operation
Egbe A, Huntley G, Connolly H, Ammash N, Deshmukh A, Khan A, Said S, Akintoye E, Warnes C, Kapa S. Outcomes of cardiac pacing in adult patients after a Fontan operation. American Heart Journal 2017, 194: 92-98. PMID: 29223440, DOI: 10.1016/j.ahj.2017.08.019.Peer-Reviewed Original ResearchConceptsDevice-related complicationsCardiovascular adverse eventsAdult Fontan patientsFontan patientsEndocardial leadsFontan operationPacemaker implantationRisk factorsEpicardial leadsCardiac pacingLead failureDevice-related infectionsReintervention rateAdult patientsAdverse eventsHeart transplantRetrospective reviewVenous thrombosisCardiac perforationMayo ClinicReinterventionPatientsLead recallDual chamberPacingPrevalence and predictors of intracranial aneurysms in patients with bicuspid aortic valve
Egbe A, Padang R, Brown R, Khan A, Luis S, Huston J, Akintoye E, Connolly H. Prevalence and predictors of intracranial aneurysms in patients with bicuspid aortic valve. Heart 2017, 103: 1508. PMID: 28596303, DOI: 10.1136/heartjnl-2016-311076.Peer-Reviewed Original ResearchMeSH KeywordsAge DistributionAgedAged, 80 and overAortic ValveBicuspid Aortic Valve DiseaseBrainEchocardiographyFemaleFollow-Up StudiesForecastingHeart Valve DiseasesHumansIntracranial AneurysmMagnetic Resonance AngiographyMaleMiddle AgedMinnesotaPrevalenceRetrospective StudiesRisk FactorsSex DistributionConceptsCoarctation of aortaBicuspid aortic valveLeft cusp fusionIntracranial aneurysmsCusp fusionAortic valveFemale genderBrain MR angiographyStudy mean ageAge tertilesRetrospective reviewCoil embolisationRisk factorsMayo ClinicHigh prevalenceAge 41General populationPatientsMR angiographyPrevalenceAneurysmsAgeRiskYearsEmbolisationPredictors of procedural complications in adult Fontan patients undergoing non-cardiac procedures
Egbe A, Khan A, Ammash N, Barbara D, Oliver W, Said S, Akintoye E, Warnes C, Connolly H. Predictors of procedural complications in adult Fontan patients undergoing non-cardiac procedures. Heart 2017, 103: 1813. PMID: 28501797, DOI: 10.1136/heartjnl-2016-311039.Peer-Reviewed Original ResearchConceptsNon-cardiac proceduresFontan patientsProcedural complicationsHeart diseaseRisk factorsAdult Fontan patientsAcute kidney injuryDialysis catheter placementMultivariable risk factorsIntensive care unitMultidisciplinary care approachCongenital heart diseaseBiventricular circulationFontan groupIntravenous diureticsAnesthesia typeCause mortalityKidney injuryAdult patientsFontan operationMinimal sedationBlood transfusionHeart failureUnplanned hospitalisationCare unit
2016
Novel biomarkers with potential for cardiovascular risk reclassification
Mallikethi-Reddy S, Briasoulis A, Akintoye E, Afonso L. Novel biomarkers with potential for cardiovascular risk reclassification. Biomarkers 2016, 22: 189-199. PMID: 27299923, DOI: 10.1080/1354750x.2016.1201540.Peer-Reviewed Original ResearchConceptsRed cell distribution widthCardiovascular risk reclassificationRisk reclassificationNovel risk markersCardiovascular risk predictionCell distribution widthCardiovascular riskCVD eventsMultivariate risk modelIntermediate riskAbsolute riskAsymptomatic individualsSerum biomarkersRisk markersTreatment recommendationsRisk factorsCystatin CNovel biomarkersRisk modelDistribution widthBiomarkersRisk predictionPatientsRiskReclassification