2020
Aortic Valve Replacement for Severe Aortic Stenosis Before and During the Era of Transcatheter Aortic Valve Implantation
Akintoye E, Ando T, Sandio A, Adegbala O, Salih M, Zubairu J, Oseni A, Sistla P, Alqasrawi M, Egbe A, Mentias A, Afonso L, Briasoulis A, Panaich S, Desai M. Aortic Valve Replacement for Severe Aortic Stenosis Before and During the Era of Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2020, 126: 73-81. PMID: 32336533, DOI: 10.1016/j.amjcard.2020.03.038.Peer-Reviewed Original ResearchConceptsSevere aortic stenosisAortic valve replacementNational Inpatient SampleTAVI eraAortic stenosisMean annual changeValve replacementFavorable short-term outcomesTranscatheter aortic valve replacementTranscatheter aortic valve implantationRate of AVRAcute kidney injuryRate of strokeAortic valve implantationShort-term outcomesRisk-adjusted ratesHospital mortalityPre-TAVIHospital outcomesKidney injuryHome dischargeHospital dischargePacemaker implantationValve implantationMedian lengthRural–Urban Disparities in Intracerebral Hemorrhage Mortality in the USA: Preliminary Findings from the National Inpatient Sample
Otite F, Akano E, Akintoye E, Khandelwal P, Malik A, Chaturvedi S, Rosand J. Rural–Urban Disparities in Intracerebral Hemorrhage Mortality in the USA: Preliminary Findings from the National Inpatient Sample. Neurocritical Care 2020, 32: 715-724. PMID: 32232726, PMCID: PMC7223184, DOI: 10.1007/s12028-020-00950-2.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAphasiaCerebral HemorrhageComorbidityCraniotomyDeglutition DisordersFemaleHealthcare DisparitiesHospital Bed CapacityHospital MortalityHospitals, RuralHospitals, UrbanHumansHydrocephalusMaleMiddle AgedRespiration, ArtificialRisk FactorsUnited StatesYoung AdultConceptsNational Inpatient SampleSex-adjusted mortalityUrban hospitalRural hospitalsICH patientsInpatient SampleJoinpoint regressionIntracerebral hemorrhage mortalityMultivariable-adjusted modelsOdds of mortalityIntracerebral hemorrhage patientsCases of ICHHospital deathHospital mortalityMultivariable adjustmentUrban patientsRural patientsStroke careHemorrhage patientsMedicare insuranceRural-urban disparitiesPatientsResultsFrom 2004HospitalMortality gapAssociation between Hospital volume of cardiopulmonary resuscitation for in-hospital cardiac arrest and survival to Hospital discharge
Akintoye E, Adegbala O, Egbe A, Olawusi E, Afonso L, Briasoulis A. Association between Hospital volume of cardiopulmonary resuscitation for in-hospital cardiac arrest and survival to Hospital discharge. Resuscitation 2020, 148: 25-31. PMID: 31945429, DOI: 10.1016/j.resuscitation.2019.12.037.Peer-Reviewed Original ResearchConceptsNational Inpatient SampleHospital cardiac arrestHospital dischargeCase volumeCardiac arrestCases of IHCAHospital case volumeMedian case volumeNon-significant trendNon-linear associationHospital volumeHome dischargeHospital CPRYounger patientsInpatient SampleCardiopulmonary resuscitationHigh comorbidityBetter survivalFirst quartileIHCAHospitalQuartilePatientsStudy periodSurvival
2019
Gender Differences in Outcomes After Implantation of Left Ventricular Assist Devices
Ahmed A, Adegbala O, Akintoye E, Inampudi C, Ajam M, Yassin A, Olawusi E, Shokr M, Alvarez P, Briasoulis A. Gender Differences in Outcomes After Implantation of Left Ventricular Assist Devices. The Annals Of Thoracic Surgery 2019, 109: 780-786. PMID: 31479642, DOI: 10.1016/j.athoracsur.2019.07.032.Peer-Reviewed Original ResearchConceptsLVAD implantationContinuous-flow LVADVentricular assist device implantationLeft ventricular assist deviceAcute kidney injuryAssist device implantationMost common complicationsExtracorporeal membrane oxygenationMedian hospitalization costNational Inpatient SamplePostoperative cardiac tamponadeLength of stayYears of ageVentricular assist deviceGender-specific differencesHospital mortalityPostoperative thromboembolismCardiac tamponadeHospital outcomesKidney injuryPeriprocedural complicationsPostoperative sepsisCommon complicationInpatient mortalityLVAD placementClinical and economic burden of heparin-induced thrombocytopenia in hospitalized patients undergoing percutaneous peripheral arterial interventions
Subahi A, Osman M, Adegbala O, Abubakar H, Kheiri B, Yassin A, Khalid M, Akintoye E, Eljack A, Osman K, Alkhouli M. Clinical and economic burden of heparin-induced thrombocytopenia in hospitalized patients undergoing percutaneous peripheral arterial interventions. Vascular 2019, 28: 81-86. PMID: 31382836, DOI: 10.1177/1708538119868615.Peer-Reviewed Original ResearchConceptsVenous thrombosis/pulmonary embolismAcute kidney injuryKidney injuryIschemic strokePulmonary embolismHigh riskDeep venous thrombosis/pulmonary embolismPercutaneous peripheral arterial interventionsICD-9-CM codesHospital mortality differenceProlonged hospital stayHospital-level characteristicsPeripheral arterial interventionsNational Inpatient SampleHospital outcomesHospital stayIntervention patientsAbsence of heparinBaseline characteristicsHome dischargeLonger hospitalizationArterial interventionsHospitalized patientsInpatient SampleThrombocytopeniaClinical Impact of Atrial Fibrillation on Short-Term Outcomes and In-Hospital Mortality in Patients with Takotsubo Syndrome: A Propensity-Matched National Study
Yassin A, Subahi A, Adegbala O, Abubakar H, Dawdy J, Mishra T, Akintoye E, Shereef H, Ghandour M, Alhusain R, Shokr M, Oviedo C, Afonso L. Clinical Impact of Atrial Fibrillation on Short-Term Outcomes and In-Hospital Mortality in Patients with Takotsubo Syndrome: A Propensity-Matched National Study. Cardiovascular Revascularization Medicine 2019, 21: 522-526. PMID: 31439442, DOI: 10.1016/j.carrev.2019.07.022.Peer-Reviewed Original ResearchConceptsCost of hospitalizationAtrial fibrillationHospital mortalityHospital complicationsVentricular arrhythmiasNational Inpatient Sample databasePropensity score-matched analysisMajor cardiac complicationsTakotsubo syndrome patientsIn-Hospital MortalityNon-routine dischargeAtrial fibrillation groupAtrial fibrillation patientsShort-term outcomesNational Inpatient SampleLength of stayPotential confounding factorsCardiac complicationsHospital stayFibrillation groupFibrillation patientsSecondary outcomesTakotsubo syndromePrimary outcomeCardiac arrestCharacteristics and Outcomes of Patients with Cardiogenic Shock Complicated by Acute Kidney Injury Requiring Hemodialysis
Inampudi C, Adegbala O, Akintoye E, Alvarez P, Briasoulis A. Characteristics and Outcomes of Patients with Cardiogenic Shock Complicated by Acute Kidney Injury Requiring Hemodialysis. The Journal Of Heart And Lung Transplantation 2019, 38: s63. DOI: 10.1016/j.healun.2019.01.141.Peer-Reviewed Original ResearchLength of stayCardiogenic shockOutcomes of patientsHospital mortalityAcute Kidney Injury Requiring HemodialysisPre-existing chronic kidney diseasePropensity score-matched groupsHigher comorbidity burdenAcute kidney injuryChronic kidney diseaseRenal replacement therapyHospital-level characteristicsRenal venous pressureNational Inpatient SampleComorbidity burdenHospital morbidityHospital outcomesKidney injuryElixhauser scoreRenal functionBiventricular functionDiabetes mellitusRenal perfusionVenous pressureHospitalization costsCardiac Implantable Electronic Devices in Adults with Tetralogy of Fallot
Egbe A, Vallabhajosyula S, Akintoye E, Deshmukh A. Cardiac Implantable Electronic Devices in Adults with Tetralogy of Fallot. The American Journal Of Cardiology 2019, 123: 1999-2001. PMID: 30961908, DOI: 10.1016/j.amjcard.2019.03.010.Peer-Reviewed Original ResearchConceptsCardiac implantable electronic devicesImplantable electronic devicesNationwide/National Inpatient SampleInflation-adjusted hospitalization costsNational Inpatient Sample databaseCharlson Comorbidity IndexMean hospital lengthPopulation-based studyNational Inpatient SampleSudden cardiac deathTetralogy of FallotTime of implantationComorbidity indexHospital lengthHospital mortalityCardiac deathTOF repairRepaired tetralogyRetrospective reviewHospitalization costsCIED implantationInpatient SampleTOF populationAdmissionObserved temporal increaseCharacteristics and Outcomes of Patients With Cardiogenic Shock Utilizing Hemodialysis for Acute Kidney Injury
Adegbala O, Inampudi C, Adejumo A, Otuonye G, Akintoye E, Elsayed R, Williams K, Alvarez P, Afonso L, Briasoulis A. Characteristics and Outcomes of Patients With Cardiogenic Shock Utilizing Hemodialysis for Acute Kidney Injury. The American Journal Of Cardiology 2019, 123: 1816-1821. PMID: 30967283, DOI: 10.1016/j.amjcard.2019.02.038.Peer-Reviewed Original ResearchConceptsLength of stayAcute kidney injuryCardiogenic shockOutcomes of patientsHospital mortalityKidney injuryTemporary mechanical supportCause of CSPropensity score-matched groupsST-elevation myocardial infarctionMechanical circulatory support devicesHigher comorbidity burdenRenal replacement therapyElevation myocardial infarctionHospital-level characteristicsRenal venous pressureNational Inpatient SampleCirculatory support devicesComorbidity burdenHospital morbidityHospital outcomesRenal functionBiventricular functionRenal perfusionVenous pressureTrends in In-Hospital Mortality, Length of Stay, Nonroutine Discharge, and Cost Among End-Stage Renal Disease Patients on Dialysis Hospitalized With Heart Failure (2001–2014)
Inampudi C, Akintoye E, Bengaluru Jayanna M, Asleh R, Briasouli A, Alvarez P, Briasoulis A. Trends in In-Hospital Mortality, Length of Stay, Nonroutine Discharge, and Cost Among End-Stage Renal Disease Patients on Dialysis Hospitalized With Heart Failure (2001–2014). Journal Of Cardiac Failure 2019, 25: 524-533. PMID: 30844441, DOI: 10.1016/j.cardfail.2019.02.020.Peer-Reviewed Original ResearchConceptsLength of stayEnd-stage renal disease patientsHF admissionsRenal disease patientsHospital mortalityNonroutine dischargeHeart failureESRD patientsDisease patientsStudy periodAnnual national ratesHF admission ratesPrevalence of comorbiditiesIn-Hospital MortalityNational Inpatient SampleCost of hospitalizationAnnual percentage changeYears of ageHF hospitalizationSecondary admissionsAdmission diagnosisComorbidity prevalencePeritoneal dialysisSubgroup analysisInpatient SampleOptimum age for performing Fontan operation in patients with univentricular heart
Akintoye E, Veldtman G, Miranda W, Connolly H, Egbe A. Optimum age for performing Fontan operation in patients with univentricular heart. Congenital Heart Disease 2019, 14: 138-139. PMID: 30945806, DOI: 10.1111/chd.12690.Peer-Reviewed Original ResearchTrends in utilization, mortality, major complications, and cost after total artificial heart implantation in the United States (2009-2015)
Briasoulis A, Akintoye E, Mohsen A, Inampudi C, Briasouli A, Asleh R, Alvarez P. Trends in utilization, mortality, major complications, and cost after total artificial heart implantation in the United States (2009-2015). Hellenic Journal Of Cardiology 2019, 61: 407-412. PMID: 30790715, DOI: 10.1016/j.hjc.2019.02.002.Peer-Reviewed Original ResearchConceptsLength of stayTotal artificial heartHospital mortalityHeart transplantationTAH implantationMajor complicationsLeft ventricular assist device implantationVentricular assist device implantationTotal artificial heart implantationComplex congenital heart diseaseStudy periodAcute kidney injuryAssist device implantationSame hospital staySevere biventricular failureDisposition of patientsNational Inpatient SampleTime of dischargeContinuous-flow LVADCost of hospitalizationArtificial heart implantationCongenital heart diseaseHospital complicationsMajor bleedingBiventricular failureTrends and Outcomes of Infective Endocarditis in Adults With Tetralogy of Fallot: A Review of the National Inpatient Sample Database
Egbe A, Vallabhajosyula S, Akintoye E, Connolly H. Trends and Outcomes of Infective Endocarditis in Adults With Tetralogy of Fallot: A Review of the National Inpatient Sample Database. Canadian Journal Of Cardiology 2019, 35: 721-726. PMID: 31151707, DOI: 10.1016/j.cjca.2019.02.006.Peer-Reviewed Original ResearchConceptsHealth care resource utilizationTetralogy of FallotProsthetic valve implantationNational Inpatient SampleCongenital heart diseaseHospital mortalityValve implantationInfective endocarditisHeart diseaseRisk factorsTOF patientsInflation-adjusted hospitalization costsNational Inpatient Sample databaseCyanotic congenital heart diseaseIncidence of endocarditisLength of stayPacemaker/defibrillatorLow socioeconomic classPopulation-based riskHospital dischargeSecondary outcomesPrimary outcomeHospitalization costsBlack raceInpatient SampleImpact of atrial fibrillation on patients hospitalized for acute myocarditis: Insights from a nationally‐representative United States cohort
Subahi A, Akintoye E, Yassin A, Abubakar H, Adegbala O, Mishra T, Abdelrahman M, Shokr M, Afonso L. Impact of atrial fibrillation on patients hospitalized for acute myocarditis: Insights from a nationally‐representative United States cohort. Clinical Cardiology 2019, 42: 26-31. PMID: 30284301, PMCID: PMC6436524, DOI: 10.1002/clc.23088.Peer-Reviewed Original ResearchConceptsAtrial fibrillationHospital mortalityHospital outcomesAcute myocarditisICD-9-CM diagnostic codesNon-routine hospital dischargeImpact of AFPropensity score-matched control groupAcute myocarditis patientsAcute kidney injuryUnited States cohortNational Inpatient SampleCardiac tamponadeCardiogenic shockCause mortalityKidney injuryMyocarditis patientsAM patientsHospital dischargeAF groupInpatient SamplePrimary diagnosisDiagnostic codesHigh riskGeneral population
2018
In‐hospital outcomes of transcatheter mitral valve repair with Mitraclip in patients with pulmonary hypertension: Insights from the National Inpatient Sample
Ahmed A, Akintoye E, Adegbala O, Yassin A, Subahi A, Bangura L, Abubakar H, Elder M, Shokr M, Afonso L. In‐hospital outcomes of transcatheter mitral valve repair with Mitraclip in patients with pulmonary hypertension: Insights from the National Inpatient Sample. Catheterization And Cardiovascular Interventions 2018, 94: e30-e36. PMID: 30506974, DOI: 10.1002/ccd.27997.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCardiac CatheterizationClinical Decision-MakingDatabases, FactualFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospital MortalityHumansHypertension, PulmonaryMaleMiddle AgedMitral ValveMitral Valve InsufficiencyPatient SelectionPostoperative ComplicationsPrevalenceProsthesis DesignRecovery of FunctionRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsTranscatheter mitral valve repairNational Inpatient SamplePulmonary hypertensionMitral valve repairHospital outcomesValve repairInpatient SamplePre-existing pulmonary hypertensionPrevalence of PHPostoperative deep vein thrombosisAcute respiratory failureCohort of patientsDeep vein thrombosisMedian hospital costsHemorrhage requiring transfusionLength of stayPH groupCardiogenic shockPostoperative sepsisRespiratory failureHome dischargeInpatient mortalityPeriprocedural outcomesProhibitive riskPulmonary embolismEffect of Hospital Ownership on Outcomes After Left Ventricular Assist Device Implantation in the United States
Briasoulis A, Inampudi C, Akintoye E, Adegbala O, Bhama J, Alvarez P. Effect of Hospital Ownership on Outcomes After Left Ventricular Assist Device Implantation in the United States. The Annals Of Thoracic Surgery 2018, 107: 527-532. PMID: 30316859, DOI: 10.1016/j.athoracsur.2018.08.051.Peer-Reviewed Original ResearchTrends in Heart failure Hospitalization, In-hospital Mortality, Length of Stay and Disposition, Among ESRD patients on Dialysis (2001-2014)
Inampudi C, Akintoye E, Alvarez P, Bhama J, Briasoulis A. Trends in Heart failure Hospitalization, In-hospital Mortality, Length of Stay and Disposition, Among ESRD patients on Dialysis (2001-2014). Journal Of Cardiac Failure 2018, 24: s104. DOI: 10.1016/j.cardfail.2018.07.393.Peer-Reviewed Original ResearchLength of stayEnd-stage renal diseasePrimary HF admissionsHospital mortalityESRD patientsHeart failureHF admissionsEnd-stage renal disease patientsStage renal disease patientsAnnual national ratesPrimary HF hospitalizationsHeart failure hospitalizationRenal disease patientsBackground Cardiovascular diseaseNational Inpatient SampleRate of admissionAnnual percentage changeHF hospitalizationFailure hospitalizationHome dischargeRenal diseaseDisease patientsInpatient SampleCardiovascular diseaseCommon causeRegional Variation in Mortality, Major Complications, and Cost After Left Ventricular Assist Device Implantation in the United States (2009 to 2014)
Briasoulis A, Inampudi C, Akintoye E, Adegbala O, Asleh R, Alvarez P, Bhama J. Regional Variation in Mortality, Major Complications, and Cost After Left Ventricular Assist Device Implantation in the United States (2009 to 2014). The American Journal Of Cardiology 2018, 121: 1575-1580. PMID: 29731117, DOI: 10.1016/j.amjcard.2018.02.047.Peer-Reviewed Original ResearchConceptsLength of stayHospital mortalityLVAD implantationMajor complicationsContinuous-flow LVAD implantationVentricular assist device implantationAssist device implantationClinical Modification codesPost-operative complicationsExtended care facilitiesNational Inpatient SampleHigher median costDiseases-Ninth RevisionPatient safety indicatorsAnnual national estimatesRisk-adjusted ratesComorbidity burdenMore patientsDevice implantationPatient populationInpatient SampleHigh percentageLVAD implantsMAIN OUTCOMEInternational ClassificationTRANSCATHETER VERSUS SURGICAL VALVE REPLACEMENT IN NON-ELDERLY (AGE LESS THAN 65): IN-HOSPITAL OUTCOMES FROM THE NATIONAL INPATIENT SAMPLE
Ando T, Akintoye E, Pahuja M, Briasoulis A, Javed A, Takagi H, Schreiber T, Grines C, Afonso L. TRANSCATHETER VERSUS SURGICAL VALVE REPLACEMENT IN NON-ELDERLY (AGE LESS THAN 65): IN-HOSPITAL OUTCOMES FROM THE NATIONAL INPATIENT SAMPLE. Journal Of The American College Of Cardiology 2018, 71: a998. DOI: 10.1016/s0735-1097(18)31539-0.Peer-Reviewed Original ResearchNational Inpatient SampleSurgical valve replacementHospital outcomesValve replacementInpatient SampleTrends in Utilization, Mortality, Major Complications, and Cost After Left Ventricular Assist Device Implantation in the United States (2009 to 2014)
Briasoulis A, Inampudi C, Akintoye E, Adegbala O, Alvarez P, Bhama J. Trends in Utilization, Mortality, Major Complications, and Cost After Left Ventricular Assist Device Implantation in the United States (2009 to 2014). The American Journal Of Cardiology 2018, 121: 1214-1218. PMID: 29525059, DOI: 10.1016/j.amjcard.2018.01.041.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAdultAgedCardiac TamponadeDatabases, FactualFemaleHealth Care CostsHeart FailureHeart-Assist DevicesHospital CostsHospital MortalityHumansLength of StayLogistic ModelsMaleMiddle AgedMortalityMyocardial InfarctionPatient DischargePostoperative ComplicationsPostoperative HemorrhageProsthesis ImplantationRenal DialysisRespiratory Tract DiseasesStrokeSurgical Wound DehiscenceSurgical Wound InfectionUnited StatesConceptsLength of stayMajor complicationsHospital mortalityLeft ventricular assist device (LVAD) implantsVentricular assist device implantsVentricular assist device implantationAssist device implantationHospital mortality rateNational Inpatient SampleTime of dischargeCost of hospitalizationSignificant decreaseAnnual national estimatesVentricular assist deviceHospital complicationsMajor bleedingCardiac tamponadeRespiratory complicationsAdult patientsIschemic strokePostoperative infectionCF-LVADCF-LVADsDevice implantationInpatient Sample