2022
Quantitative Echocardiographic Assessment and Optimal Criteria for Early Intervention in Asymptomatic Tricuspid Regurgitation
Akintoye E, Wang T, Nakhla M, Ali A, Fava A, Akyuz K, Popovic Z, Pettersson G, Gillinov A, Xu B, Griffin B, Desai M. Quantitative Echocardiographic Assessment and Optimal Criteria for Early Intervention in Asymptomatic Tricuspid Regurgitation. JACC Cardiovascular Imaging 2022, 16: 13-24. PMID: 36274042, DOI: 10.1016/j.jcmg.2022.08.004.Peer-Reviewed Original ResearchConceptsTricuspid regurgitationMedian survival timeRisk factorsAsymptomatic patientsEchocardiographic parametersSurvival timeEarly interventionOptimal timingRight heart parametersSymptomatic tricuspid regurgitationSignificant tricuspid regurgitationFree wall strainHigh operative mortalitySex-matched cohortQuantitative echocardiographic assessmentKey prognostic markersCause mortalityOperative mortalityTR patientsEchocardiographic assessmentLate presentationPoor outcomePrognostic utilityPrognostic valuePrognostic marker
2020
Intermediate and Late Outcomes With PCI vs CABG for Left Main Disease — Landmark Meta-Analysis of Randomized Trials
Akintoye E, Salih M, Olagoke O, Oseni A, Sistla P, Alqasrawi M, Panos A, Panaich S, Sellke F. Intermediate and Late Outcomes With PCI vs CABG for Left Main Disease — Landmark Meta-Analysis of Randomized Trials. Cardiovascular Revascularization Medicine 2020, 23: 114-118. PMID: 32921597, DOI: 10.1016/j.carrev.2020.08.040.Peer-Reviewed Original ResearchConceptsUnprotected left main diseaseLeft main diseaseEXCEL trialLate mortalityCause mortalityDirection of associationRandomized trialsLate outcomesCABGLate MIMain diseaseReasonable alternativePCITrialsSignificant differencesRCTsLower ratesHigh rateMortalityYearsLong termPatientsMixed resultsPRECOMBATStroke
2019
Impact of atrial fibrillation on patients hospitalized for acute myocarditis: Insights from a nationally‐representative United States cohort
Subahi A, Akintoye E, Yassin A, Abubakar H, Adegbala O, Mishra T, Abdelrahman M, Shokr M, Afonso L. Impact of atrial fibrillation on patients hospitalized for acute myocarditis: Insights from a nationally‐representative United States cohort. Clinical Cardiology 2019, 42: 26-31. PMID: 30284301, PMCID: PMC6436524, DOI: 10.1002/clc.23088.Peer-Reviewed Original ResearchConceptsAtrial fibrillationHospital mortalityHospital outcomesAcute myocarditisICD-9-CM diagnostic codesNon-routine hospital dischargeImpact of AFPropensity score-matched control groupAcute myocarditis patientsAcute kidney injuryUnited States cohortNational Inpatient SampleCardiac tamponadeCardiogenic shockCause mortalityKidney injuryMyocarditis patientsAM patientsHospital dischargeAF groupInpatient SamplePrimary diagnosisDiagnostic codesHigh riskGeneral population
2018
Venous congestion and pulmonary vascular function in Fontan circulation: Implications for prognosis and treatment
Egbe A, Reddy Y, Khan A, Al-Otaibi M, Akintoye E, Obokata M, Borlaug B. Venous congestion and pulmonary vascular function in Fontan circulation: Implications for prognosis and treatment. International Journal Of Cardiology 2018, 271: 312-316. PMID: 30223363, PMCID: PMC6146405, DOI: 10.1016/j.ijcard.2018.05.039.Peer-Reviewed Original ResearchConceptsPulmonary vascular resistance indexCentral venous pressureSystemic venous congestionPulmonary vascular functionFontan patientsVenous congestionFontan circulationVascular functionElevated pulmonary vascular resistance indexAdult Fontan patientsVascular resistance indexPulmonary blood flowSub-pulmonary ventricleCongenital heart diseaseLow-level elevationsPulmonary vascular structureFontan groupFontan populationAntiplatelet therapyCause mortalityCardiac catheterizationComposite endpointVenous pressureMulticenter studyAdverse outcomesSafety and Efficacy of Novel Oral Anticoagulants Versus Warfarin in Medicare Beneficiaries With Atrial Fibrillation and Valvular Heart Disease
Briasoulis A, Inampudi C, Akintoye E, Alvarez P, Panaich S, Vaughan‐Sarrazin M. Safety and Efficacy of Novel Oral Anticoagulants Versus Warfarin in Medicare Beneficiaries With Atrial Fibrillation and Valvular Heart Disease. Journal Of The American Heart Association 2018, 7: e008773. PMID: 29622591, PMCID: PMC6015407, DOI: 10.1161/jaha.118.008773.Peer-Reviewed Original ResearchConceptsValvular heart diseaseAtrial fibrillationMedicare beneficiariesIschemic strokeHeart diseaseNew-onset atrial fibrillationNon-vitamin K anticoagulantsGastrointestinal bleeding ratesLarge community-based samplePropensity-matched sampleCommunity-based sampleMajor bleedingNongastrointestinal bleedingCause mortalitySystemic thromboembolismVersus WarfarinPrimary outcomePropensity matchingMyocardial infarctionBleeding rateLower riskPatientsRivaroxabanWarfarinDabigatran
2017
Predictors of procedural complications in adult Fontan patients undergoing non-cardiac procedures
Egbe A, Khan A, Ammash N, Barbara D, Oliver W, Said S, Akintoye E, Warnes C, Connolly H. Predictors of procedural complications in adult Fontan patients undergoing non-cardiac procedures. Heart 2017, 103: 1813. PMID: 28501797, DOI: 10.1136/heartjnl-2016-311039.Peer-Reviewed Original ResearchConceptsNon-cardiac proceduresFontan patientsProcedural complicationsHeart diseaseRisk factorsAdult Fontan patientsAcute kidney injuryDialysis catheter placementMultivariable risk factorsIntensive care unitMultidisciplinary care approachCongenital heart diseaseBiventricular circulationFontan groupIntravenous diureticsAnesthesia typeCause mortalityKidney injuryAdult patientsFontan operationMinimal sedationBlood transfusionHeart failureUnplanned hospitalisationCare unitComparison of Hospital Outcome of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Diabetes Mellitus (from the Nationwide Inpatient Sample)
Ando T, Akintoye E, Telila T, Briasoulis A, Takagi H, Slovut D, Schreiber T, Grines C, Afonso L. Comparison of Hospital Outcome of Transcatheter Versus Surgical Aortic Valve Replacement in Patients With Diabetes Mellitus (from the Nationwide Inpatient Sample). The American Journal Of Cardiology 2017, 119: 1250-1254. PMID: 28219665, DOI: 10.1016/j.amjcard.2016.12.026.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAgedAged, 80 and overBlood TransfusionDatabases, FactualDiabetes MellitusExtracorporeal Membrane OxygenationFemaleHeart Valve Prosthesis ImplantationHospital CostsHospital MortalityHumansLength of StayMaleMyocardial InfarctionPacemaker, ArtificialPostoperative ComplicationsSepsisTranscatheter Aortic Valve ReplacementUnited StatesConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementTAVR patientsValve replacementDM patientsHospital outcomesOdds ratioOutcomes of TAVRTranscatheter Versus Surgical Aortic Valve ReplacementNationwide Inpatient Sample databasePrimary end pointNew pacemaker implantationDiabetes mellitus patientsMean hospitalization costAcute myocardial infarctionLength of staySAVR patientsSAVR proceduresCardiac complicationsCause mortalityPerioperative complicationsPostoperative sepsisRespiratory complicationsVascular complications