2024
Community perspectives on adolescent mental health stigma in American Samoa
Blas V, Mew E, Winschel J, Hunt L, Soliai Lemusu S, Lowe S, Naseri J, Toelupe R, Hawley N, McCutchan-Tofaeono J. Community perspectives on adolescent mental health stigma in American Samoa. 2024, 1: e0000080. DOI: 10.1371/journal.pmen.0000080.Peer-Reviewed Original ResearchMental health stigmaHealth stigmaSelf-stigma of mental illnessLevels of mental health stigmaMental illness-related stigmaMental health care accessIllness-related stigmaHealth care accessMental health burdenMental health servicesStigmatization of mental healthMental health needsSocio-ecological modelMental health challengesMental health concernsMental health stigmatizationOnline focus groupsAmerican SamoaCare accessSelf-stigmaPerceived stigmatizationHealth needsHealth servicesMental illnessMental healthO le tagata ma lona aiga, o le tagata ma lona fa’asinomaga (Every person belongs to a family and every family belongs to a person): Development of a parenting framework for adolescent mental wellbeing in American Samoa
Mew E, Hunt L, Toelupe R, Blas V, Winschel J, Naseri J, Soliai-Lemusu S, Tofaeono J, Seui M, Ledoux-Sunia T, Sunia F, Reid A, Helsham D, Lowe S, Poulin R, Hawley N, McCutchan-Tofaeono J. O le tagata ma lona aiga, o le tagata ma lona fa’asinomaga (Every person belongs to a family and every family belongs to a person): Development of a parenting framework for adolescent mental wellbeing in American Samoa. Children And Youth Services Review 2024, 160: 107502. PMID: 38946713, PMCID: PMC11209950, DOI: 10.1016/j.childyouth.2024.107502.Peer-Reviewed Original ResearchPromote adolescent mental healthAdolescent mental healthAdolescent mental wellbeingMental health problemsMental healthMental wellbeingParenting programsPrevalence of mental health problemsCaregiver mental healthHealth problemsHealth system effortsPromote mental healthCommunity members' perspectivesSemi-structured in-depth interviewsHealthy coping strategiesAdolescent participantsSamoan communityFamily-based interventionsRegion of residenceAdult key informantsDeductive thematic analysisEvidence-based frameworkSemi-structured interviewsCommunity-partneredIn-depth interviews
2022
Guidelines for Reporting Outcomes in Trial Protocols
Butcher N, Monsour A, Mew E, Chan A, Moher D, Mayo-Wilson E, Terwee C, Chee-A-Tow A, Baba A, Gavin F, Grimshaw J, Kelly L, Saeed L, Thabane L, Askie L, Smith M, Farid-Kapadia M, Williamson P, Szatmari P, Tugwell P, Golub R, Monga S, Vohra S, Marlin S, Ungar W, Offringa M. Guidelines for Reporting Outcomes in Trial Protocols. JAMA 2022, 328: 2345-2356. PMID: 36512367, DOI: 10.1001/jama.2022.21243.Peer-Reviewed Original ResearchGuidelines for Reporting Outcomes in Trial Reports
Butcher N, Monsour A, Mew E, Chan A, Moher D, Mayo-Wilson E, Terwee C, Chee-A-Tow A, Baba A, Gavin F, Grimshaw J, Kelly L, Saeed L, Thabane L, Askie L, Smith M, Farid-Kapadia M, Williamson P, Szatmari P, Tugwell P, Golub R, Monga S, Vohra S, Marlin S, Ungar W, Offringa M. Guidelines for Reporting Outcomes in Trial Reports. JAMA 2022, 328: 2252-2264. PMID: 36511921, DOI: 10.1001/jama.2022.21022.Peer-Reviewed Original ResearchConceptsCONSORT 2010 statementClinical trialsConsensus meetingTrial reportsTrial outcomesReporting outcomesReporting Trials (CONSORT) 2010 statementTrial resultsElectronic database searchReporting of outcomesPerson consensus meetingCochrane Methodology RegisterGrey literature searchReference list searchesPrespecified analysisSecondary outcomesConsensus-based standardsDelphi survey processConsolidated StandardsDelphi votingTreatment groupsOutcome selectionFurther evaluationEvidence-informed decisionLiterature searchPsychosocial family-level mediators in the intergenerational transmission of trauma: Protocol for a systematic review and meta-analysis
Mew E, Nyhan K, Bonumwezi J, Blas V, Gorman H, Hennein R, Quach K, Shabanova V, Hawley N, Lowe S. Psychosocial family-level mediators in the intergenerational transmission of trauma: Protocol for a systematic review and meta-analysis. PLOS ONE 2022, 17: e0276753. PMID: 36378630, PMCID: PMC9665367, DOI: 10.1371/journal.pone.0276753.Peer-Reviewed Original ResearchConceptsChild mental health outcomesSystematic review registrationRelevant study characteristicsMental health outcomesParental trauma exposureReview registrationBias assessmentRegistration IDConference abstractsPeer-reviewed publicationsPsychosocial factorsFamily-level factorsHealth outcomesSystematic reviewNarrative synthesisPsychosocial mediatorsPublication biasTrauma exposureStudy characteristicsEpidemiological researchProQuest DissertationsTraumaTrauma typesPsychological impactMediators55 SPIRIT-outcomes and CONSORT-outcomes: enhanced trial outcome transparency, less bias, improved systematic reviews, better health
Butcher N, Monsour A, Mew E, Askie L, Grimshaw J, Moher D, Chan A, Gavin F, Smith M, Offringa M. 55 SPIRIT-outcomes and CONSORT-outcomes: enhanced trial outcome transparency, less bias, improved systematic reviews, better health. 2022, a3.2-a4. DOI: 10.1136/ebm-2022-ebmlive.6.Peer-Reviewed Original ResearchTrauma as a Public Health Issue: Epidemiology of Trauma and Trauma-Related Disorders
Mew E, Koenen K, Lowe S. Trauma as a Public Health Issue: Epidemiology of Trauma and Trauma-Related Disorders. 2022, 13-40. DOI: 10.1007/978-3-030-97802-0_2.Peer-Reviewed Original ResearchTrauma-related disordersGlobal public health burdenMajor public health concernEpidemiology of traumaPublic health burdenPublic health approachPublic health issuePublic health concernDeterminants of diseaseHealth burdenHigh prevalenceEpidemiologic studiesGlobal prevalenceEpidemiological studiesHealth problemsTrauma exposureHealth approachHealth concernPTE exposureHealth issuesDisordersTraumaCross-study comparisonsPublic healthEpidemiology170 SPIRIT-outcomes and CONSORT-outcomes: enhanced trial outcome transparency, less bias, improved systematic reviews, better health
Butcher N, Monsour A, Mew E, Askie L, Grimshaw J, Moher D, Chan A, Gavin F, Smith M, Offringa M. 170 SPIRIT-outcomes and CONSORT-outcomes: enhanced trial outcome transparency, less bias, improved systematic reviews, better health. 2022, a45-a45. DOI: 10.1136/bmjebm-2022-podabstracts.91.Peer-Reviewed Original Research
2021
Anticipating the long-term neurodevelopmental impact of the COVID-19 pandemic on newborns and infants: A call for research and preventive policy
McDonald AJ, Mew EJ, Hawley NL, Lowe SR. Anticipating the long-term neurodevelopmental impact of the COVID-19 pandemic on newborns and infants: A call for research and preventive policy. Journal Of Affective Disorders Reports 2021, 6: 100213. PMID: 34514459, PMCID: PMC8417611, DOI: 10.1016/j.jadr.2021.100213.Peer-Reviewed Original ResearchLong-term neurodevelopmental impactCOVID-19 pandemicPrenatal maternal stressEarly childhood adversityPandemic-related stressMental health policyFuture mental healthPregnant womenMaternal stressNeurodevelopmental impactChildhood adversityGlobal cohortNew mothersHealth policyMental healthEarly lifeNewbornsInfantsPreventive policiesNeurodevelopmentPandemicHigh levelsCohortMonthsWomenEmergency care with lay responders in underserved populations: a systematic review
Orkin A, Venugopal J, Curran J, Fortune M, McArthur A, Mew E, Ritchie S, Drennan I, Exley A, Jamieson R, Johnson D, MacPherson A, Martiniuk A, McDonald N, Osei-Ampofo M, Wegier P, Van de Velde S, VanderBurgh D. Emergency care with lay responders in underserved populations: a systematic review. Bulletin Of The World Health Organization 2021, 99: 514-528h. PMID: 34248224, PMCID: PMC8243031, DOI: 10.2471/blt.20.270249.Peer-Reviewed Original ResearchConceptsLow-resource settingsEmergency careOpioid poisoningUnderserved populationsLow-resource populationsEmergency care trainingCommunity health effectsPediatric malariaMiddle-income countriesCardiac arrestPatient morbidityStudy eligibilityEligible studiesPatient outcomesHigh-income countriesInclusion criteriaAdditional grey literatureHealth of individualsRisk populationsCare professionalsModerate qualitySystematic reviewCommunicable diseasesCare trainingMost studies
2020
Development of an international standard set of patient-centred outcome measures for overall paediatric health: a consensus process
Algurén B, Ramirez J, Salt M, Sillett N, Myers S, Alvarez-Cote A, Butcher N, Caneo L, Cespedes J, Chaplin J, Ng K, García-García J, Hazelzet J, Klassen A, Turquetto A, Mew E, Morris M, Offringa M, O'Meara M, Papp J, Rodrigo C, Switaj T, Mayer C, Jenkins K. Development of an international standard set of patient-centred outcome measures for overall paediatric health: a consensus process. Archives Of Disease In Childhood 2020, 106: 868-876. PMID: 33310707, PMCID: PMC8380885, DOI: 10.1136/archdischild-2020-320345.Peer-Reviewed Original ResearchConceptsOutcome measuresPatient-centered outcome measuresDelphi processHealth Professional SurveyPatient-reported outcomesCase-mix variablesClinician-reported measuresField of pediatricsHealth Outcomes MeasurementAdolescent physical healthWorking GroupInternational Working GroupClinical trialsPediatric healthcare deliveryProxy-reported outcomesHealth SurveyPediatric healthInternational standard setOutcome measurementsPatient advisorsBiopsychosocial aspectsPatient validationPhysical healthHealth conditionsFamily medicineResponse to “Trials for depressive disorder in adolescents: the emperor's new clothes,” a letter to the editor by Alain Braillon, MD, PhD
Butcher N, Mew E, Monsour A, Szatmari P, Monga S, Offringa M, co-authors A. Response to “Trials for depressive disorder in adolescents: the emperor's new clothes,” a letter to the editor by Alain Braillon, MD, PhD. Journal Of Clinical Epidemiology 2020, 128: 159-161. PMID: 32860976, PMCID: PMC7449977, DOI: 10.1016/j.jclinepi.2020.08.010.Peer-Reviewed Original ResearchOutcome reporting recommendations for clinical trial protocols and reports: a scoping review
Butcher N, Mew E, Monsour A, Chan A, Moher D, Offringa M. Outcome reporting recommendations for clinical trial protocols and reports: a scoping review. Trials 2020, 21: 620. PMID: 32641085, PMCID: PMC7341657, DOI: 10.1186/s13063-020-04440-w.Peer-Reviewed Original ResearchConceptsClinical trial protocolTrial protocolTrial outcomesStandard Protocol ItemsReporting of outcomesElectronic bibliographic database searchConsensus-based guidanceFull-text screeningGrey literature searchInterventional trialsResultsIn totalClinical trialsBibliographic database searchConsolidated StandardsProtocol ItemsCandidate itemsOutcome selectionAbstract screeningLiterature searchOutcomesResearch wasteSystematic scoping review identifies heterogeneity in outcomes measured in adolescent depression clinical trials
Mew E, Monsour A, Saeed L, Santos L, Patel S, Courtney D, Watson P, Szatmari P, Offringa M, Monga S, Butcher N. Systematic scoping review identifies heterogeneity in outcomes measured in adolescent depression clinical trials. Journal Of Clinical Epidemiology 2020, 126: 71-79. PMID: 32561367, DOI: 10.1016/j.jclinepi.2020.06.013.Peer-Reviewed Original ResearchConceptsOutcome measurement instrumentsOutcome heterogeneityMajor depressive disorder trialsMajor depressive disorderDepressive symptom severityOutcome termsSingle trialDepression clinical trialPrimary outcomeClinical trialsDepressive disorderDepression trialsSymptom severityLife impactStudy designIdentified outcomesTrial resultsTrialsOutcomesIdentifies heterogeneityDescriptive analysisMeasurement instrumentsTherapySeverityPrimary outcome reporting in adolescent depression clinical trials needs standardization
Monsour A, Mew E, Patel S, Chee-a-tow A, Saeed L, Santos L, Courtney D, Watson P, Monga S, Szatmari P, Offringa M, Butcher N. Primary outcome reporting in adolescent depression clinical trials needs standardization. BMC Medical Research Methodology 2020, 20: 129. PMID: 32450810, PMCID: PMC7247139, DOI: 10.1186/s12874-020-01019-6.Peer-Reviewed Original ResearchConceptsRandomized clinical trialsPrimary outcomeSingle primary outcomeClinical trialsOutcome assessmentDiagnosis of MDDChecklist itemsOutcome assessorsDepression clinical trialClinical guidelinesAdolescent MDDOutcome analysisRCT publicationsMost trialsTrial publicationsOutcome reportingReporting ItemsTreatment interventionsTrial outcomesOutcome informationTrialsHealth careOutcomesSignificant differencesMinimal criteriaNeurodevelopmental outcome descriptions in cohorts of extremely preterm children
Ding S, Mew E, Chee-A-Tow A, Offringa M, Butcher N, Moore G. Neurodevelopmental outcome descriptions in cohorts of extremely preterm children. Archives Of Disease In Childhood - Fetal And Neonatal Edition 2020, 105: fetalneonatal-2019-318144. PMID: 31932362, DOI: 10.1136/archdischild-2019-318144.Peer-Reviewed Original ResearchConceptsCohort studyCerebral palsyCognitive functionNeurodevelopmental outcomesOutcome selectionProspective cohort studyLong-term followOutcome descriptionsCompleteness of outcomeCompleteness of reportingOutcome assessorsPreterm infantsPreterm birthOutcome definitionsPreterm childrenOutcome reportingPalsyOutcomesInfantsChildrenReportingPretermStudy resultsCohortFollow
2019
Improving outcome reporting in clinical trial reports and protocols: study protocol for the Instrument for reporting Planned Endpoints in Clinical Trials (InsPECT)
Butcher NJ, Monsour A, Mew EJ, Szatmari P, Pierro A, Kelly LE, Farid-Kapadia M, Chee-a-tow A, Saeed L, Monga S, Ungar W, Terwee CB, Vohra S, Fergusson D, Askie LM, Williamson PR, Chan AW, Moher D, Offringa M. Improving outcome reporting in clinical trial reports and protocols: study protocol for the Instrument for reporting Planned Endpoints in Clinical Trials (InsPECT). Trials 2019, 20: 161. PMID: 30841935, PMCID: PMC6404348, DOI: 10.1186/s13063-019-3248-0.Peer-Reviewed Original ResearchConceptsClinical trialsTrial protocolTrial reportsExpert consensus meetingClinical trial reportsCONSORT reporting guidelinesIntegrated knowledge translation approachSystematic review authorsKnowledge translation approachReview authorsConsensus-based standardsPatient outcomesConsensus meetingDiverse disease areasInternational Delphi studyTrial designGuideline developersGuideline developmentCONSORT extensionDelphi studyTrial outcomesEQUATOR NetworkCandidate outcomesTrialsPoor quality outcomesGuidance for reporting outcomes in clinical trials: scoping review protocol
Butcher NJ, Mew EJ, Saeed L, Monsour A, Chee-A-Tow A, Chan AW, Moher D, Offringa M. Guidance for reporting outcomes in clinical trials: scoping review protocol. BMJ Open 2019, 9: e023001. PMID: 30782872, PMCID: PMC6377514, DOI: 10.1136/bmjopen-2018-023001.Peer-Reviewed Original ResearchOutcomes reported in randomised clinical trials of major depressive disorder treatments in adolescents: a systematic scoping review protocol
Monsour A, Mew EJ, Szatmari P, Patel S, Saeed L, Offringa M, Butcher NJ. Outcomes reported in randomised clinical trials of major depressive disorder treatments in adolescents: a systematic scoping review protocol. BMJ Open 2019, 9: bmjopen-2018-024191. PMID: 30782729, PMCID: PMC6340428, DOI: 10.1136/bmjopen-2018-024191.Peer-Reviewed Original ResearchConceptsAdolescent major depressive disorderCore outcome setsMajor depressive disorderClinical trialsMajor depressive disorder treatmentCommon mental health conditionsDepressive disorder treatmentBest treatment practicesMental health conditionsElectronic bibliographic database searchJoanna Briggs InstituteReview methods manualFull-text screeningEfficacy of interventionsSystematic scoping review protocolScoping review protocolSystematic scoping reviewDepressive disorderEligible studiesBibliographic database searchOutcome setsTreatment interventionsDisorder treatmentOutcome selectionRCTs
2018
Defining and measuring health equity effects in research on task shifting interventions in high-income countries: a systematic review protocol
Orkin AM, McArthur A, McDonald A, Mew EJ, Martiniuk A, Buchman DZ, Kouyoumdjian F, Rachlis B, Strike C, Upshur R. Defining and measuring health equity effects in research on task shifting interventions in high-income countries: a systematic review protocol. BMJ Open 2018, 8: e021172. PMID: 30068611, PMCID: PMC6074666, DOI: 10.1136/bmjopen-2017-021172.Peer-Reviewed Original ResearchConceptsPROGRESS-Plus frameworkHealth equityHigh-income countriesBaseline statusHealth inequitiesOpen-access peer-reviewed publicationHigh-income settingsHealth equity effectsSystematic review protocolQuality of reportingDisease burdenEligible studiesEffective treatmentPeer-reviewed publicationsAcademic conference presentationsHealth disadvantageSystematic reviewNarrative synthesisAbstract screeningReview protocolIntervention impactManual searchingInterventionHuman subjectsDuplicate titles