2020
Development of an international standard set of patient-centred outcome measures for overall paediatric health: a consensus process
Algurén B, Ramirez J, Salt M, Sillett N, Myers S, Alvarez-Cote A, Butcher N, Caneo L, Cespedes J, Chaplin J, Ng K, García-García J, Hazelzet J, Klassen A, Turquetto A, Mew E, Morris M, Offringa M, O'Meara M, Papp J, Rodrigo C, Switaj T, Mayer C, Jenkins K. Development of an international standard set of patient-centred outcome measures for overall paediatric health: a consensus process. Archives Of Disease In Childhood 2020, 106: 868-876. PMID: 33310707, PMCID: PMC8380885, DOI: 10.1136/archdischild-2020-320345.Peer-Reviewed Original ResearchConceptsOutcome measuresPatient-centered outcome measuresDelphi processHealth Professional SurveyPatient-reported outcomesCase-mix variablesClinician-reported measuresField of pediatricsHealth Outcomes MeasurementAdolescent physical healthWorking GroupInternational Working GroupClinical trialsPediatric healthcare deliveryProxy-reported outcomesHealth SurveyPediatric healthInternational standard setOutcome measurementsPatient advisorsBiopsychosocial aspectsPatient validationPhysical healthHealth conditionsFamily medicineSystematic scoping review identifies heterogeneity in outcomes measured in adolescent depression clinical trials
Mew E, Monsour A, Saeed L, Santos L, Patel S, Courtney D, Watson P, Szatmari P, Offringa M, Monga S, Butcher N. Systematic scoping review identifies heterogeneity in outcomes measured in adolescent depression clinical trials. Journal Of Clinical Epidemiology 2020, 126: 71-79. PMID: 32561367, DOI: 10.1016/j.jclinepi.2020.06.013.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildClinical Decision-MakingClinical Trials as TopicData ManagementDepressive Disorder, MajorHumansOutcome Assessment, Health CareRandomized Controlled Trials as TopicConceptsOutcome measurement instrumentsOutcome heterogeneityMajor depressive disorder trialsMajor depressive disorderDepressive symptom severityOutcome termsSingle trialDepression clinical trialPrimary outcomeClinical trialsDepressive disorderDepression trialsSymptom severityLife impactStudy designIdentified outcomesTrial resultsTrialsOutcomesIdentifies heterogeneityDescriptive analysisMeasurement instrumentsTherapySeverityPrimary outcome reporting in adolescent depression clinical trials needs standardization
Monsour A, Mew E, Patel S, Chee-a-tow A, Saeed L, Santos L, Courtney D, Watson P, Monga S, Szatmari P, Offringa M, Butcher N. Primary outcome reporting in adolescent depression clinical trials needs standardization. BMC Medical Research Methodology 2020, 20: 129. PMID: 32450810, PMCID: PMC7247139, DOI: 10.1186/s12874-020-01019-6.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChecklistDepressionDepressive Disorder, MajorHumansOutcome Assessment, Health CareReference StandardsConceptsRandomized clinical trialsPrimary outcomeSingle primary outcomeClinical trialsOutcome assessmentDiagnosis of MDDChecklist itemsOutcome assessorsDepression clinical trialClinical guidelinesAdolescent MDDOutcome analysisRCT publicationsMost trialsTrial publicationsOutcome reportingReporting ItemsTreatment interventionsTrial outcomesOutcome informationTrialsHealth careOutcomesSignificant differencesMinimal criteria
2019
Outcomes reported in randomised clinical trials of major depressive disorder treatments in adolescents: a systematic scoping review protocol
Monsour A, Mew EJ, Szatmari P, Patel S, Saeed L, Offringa M, Butcher NJ. Outcomes reported in randomised clinical trials of major depressive disorder treatments in adolescents: a systematic scoping review protocol. BMJ Open 2019, 9: bmjopen-2018-024191. PMID: 30782729, PMCID: PMC6340428, DOI: 10.1136/bmjopen-2018-024191.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentDepressive Disorder, MajorHumansOutcome Assessment, Health CareRandomized Controlled Trials as TopicConceptsAdolescent major depressive disorderCore outcome setsMajor depressive disorderClinical trialsMajor depressive disorder treatmentCommon mental health conditionsDepressive disorder treatmentBest treatment practicesMental health conditionsElectronic bibliographic database searchJoanna Briggs InstituteReview methods manualFull-text screeningEfficacy of interventionsSystematic scoping review protocolScoping review protocolSystematic scoping reviewDepressive disorderEligible studiesBibliographic database searchOutcome setsTreatment interventionsDisorder treatmentOutcome selectionRCTs