2011
Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats
Gracheva EO, Cordero-Morales JF, González-Carcacía JA, Ingolia NT, Manno C, Aranguren CI, Weissman JS, Julius D. Ganglion-specific splicing of TRPV1 underlies infrared sensation in vampire bats. Nature 2011, 476: 88-91. PMID: 21814281, PMCID: PMC3535012, DOI: 10.1038/nature10245.Peer-Reviewed Original ResearchConceptsVampire batsGene sequencesWarm-blooded preyGroup of snakesDifferent molecular mechanismsVertebrate lineageRNA splicingMolecular dataSensitive ion channelsMolecular mechanismsIon channelsBatsHeat-sensitive channelSplicingPit organsSnakesLineagesPreySequenceHot spotsDolphinsUnderliesRodentsVariants
2002
Activation of p38 MAP-Kinase and Caldesmon Phosphorylation Are Essential for Urokinase-Induced Human Smooth Muscle Cell Migration
Goncharova E, Vorotnikov A, Gracheva E, Wang C, Panettieri R, Stepanova V, Tkachuk V. Activation of p38 MAP-Kinase and Caldesmon Phosphorylation Are Essential for Urokinase-Induced Human Smooth Muscle Cell Migration. Biological Chemistry 2002, 383: 115-126. PMID: 11930938, DOI: 10.1515/bc.2002.012.Peer-Reviewed Original ResearchMeSH KeywordsCalmodulin-Binding ProteinsCell MovementHumansKringlesMitogen-Activated Protein Kinase 1Mitogen-Activated Protein Kinase 3Mitogen-Activated Protein KinasesMuscle, Smooth, VascularP38 Mitogen-Activated Protein KinasesPhosphorylationProtein Structure, TertiaryRecombinant ProteinsTracheaUrokinase-Type Plasminogen ActivatorConceptsP38 MAP kinaseMAP kinaseUPA mutantsKringle domainsHuman airway smooth muscle cellsSmooth muscle cell migrationCaldesmon phosphorylationMuscle cell migrationMAP kinase sitesP38 MAP kinase pathwayCell migrationNon-muscle caldesmonMAP kinase pathwayMAP kinase activationP38 MAP kinase activationMyosin regulatory light chainHuman smooth muscle cell migrationUrokinase-type plasminogen activatorRegulatory light chainProtein caldesmonCell motilityDownstream phosphorylationSer-19PhosphorylationIntracellular pathways