James Smith, MD
About
Appointments
Nephrology
Associate Clinical ProfessorPrimary
Other Departments & Organizations
- Internal Medicine
- Kidney Transplant Program
- Liver & Pancreas Transplant Program
- Nephrology
Education & Training
- Fellowship
- Yale University School of Medicine (1982)
- Residency
- Waterbury Hospital (1978)
- MD
- University of Kentucky (1974)
- Internship
- Waterbury Hospital (1974)
Board Certifications
Nephrology
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 1980
Internal Medicine
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 1978
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of James Smith's published research.
Publications Timeline
A big-picture view of James Smith's research output by year.
Courtney Elizabeth Gibson, MD, MS, FACS
Margaret Bia, MD
Ricarda Tomlin
Richard Formica, MD
Sanjay Kulkarni, MD, MHCM, FACS
6Publications
420Citations
Publications
2016
Parathyroidectomy prior to kidney transplant decreases graft failure
Callender GG, Malinowski J, Javid M, Zhang Y, Huang H, Quinn CE, Carling T, Tomlin R, Smith JD, Kulkarni S. Parathyroidectomy prior to kidney transplant decreases graft failure. Surgery 2016, 161: 44-50. PMID: 27863776, DOI: 10.1016/j.surg.2016.10.003.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsMeSH KeywordsAdultAgedAged, 80 and overCohort StudiesConfidence IntervalsDatabases, FactualFemaleGraft RejectionGraft SurvivalHumansHyperparathyroidismKidney Failure, ChronicKidney TransplantationMaleMiddle AgedOdds RatioParathyroid HormoneParathyroidectomyPreoperative CareRetrospective StudiesRisk AssessmentTreatment OutcomeConceptsYear post-kidney transplantationPost-kidney transplantationDelayed graft functionGraft failureKidney transplantationGraft functionParathyroid hormoneUremic hyperparathyroidismKidney diseaseFirst year post-kidney transplantationSerum parathyroid hormone levelsCurrent Kidney DiseaseGlobal Outcomes (KDIGO) guidelinesParathyroid hormone levelsSerum parathyroid hormoneAdult patientsKidney transplantOutcomes guidelinesRetrospective reviewSingle institutionCurrent guidelinesHormone levelsSurvival 1ParathyroidectomyTransplantation
2006
A randomized trial comparing losartan with amlodipine as initial therapy for hypertension in the early post-transplant period
Formica RN, Friedman AL, Lorber MI, Smith JD, Eisen T, Bia MJ. A randomized trial comparing losartan with amlodipine as initial therapy for hypertension in the early post-transplant period. Nephrology Dialysis Transplantation 2006, 21: 1389-1394. PMID: 16431893, DOI: 10.1093/ndt/gfk058.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsMeSH KeywordsAdultAgedAmlodipineBlood Pressure DeterminationChi-Square DistributionDose-Response Relationship, DrugDrug Administration ScheduleFemaleFollow-Up StudiesHumansHypertensionKidney Failure, ChronicKidney TransplantationLosartanMaleMiddle AgedProbabilityRisk AssessmentSeverity of Illness IndexTreatment OutcomeConceptsRenal transplant recipientsPost-transplant periodEarly post-transplant periodARB useUse of ARBInitial therapyCCB groupImmediate post-transplant periodPost-transplant erythrocytosisPost-transplant hypertensionRisk of hyperkalaemiaPost-transplant managementSerum creatinine levelsChronic kidney diseaseII receptor blockersCalcium channel blockersNumber of patientsAldosterone systemARB groupKidney transplantationRenal transplantationTransplant recipientsCreatinine levelsRenal functionBlood pressure
1989
Insulin resistance in uremia: An in vivo and in vitro study
Stein P, Hunt W, Johnson C, DeFronzo R, Smith J. Insulin resistance in uremia: An in vivo and in vitro study. Metabolism 1989, 38: 562-567. PMID: 2657327, DOI: 10.1016/0026-0495(89)90217-5.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsUremic ratsAbility of insulinInsulin resistanceSoleus muscleTotal body glucose disposalEuglycemic insulin clamp techniqueInsulin clamp techniqueUremic rat modelHepatic glucose productionPair-fed controlsChronic uremiaGlucose disposalRat modelGlucose metabolismClamp techniqueGlucose productionMetabolic defectsInsulinRatsUremiaGlycogen synthesisGlucose oxidationMuscleVivoOxidative pathway
1985
Is glucose intolerance harmful for the uremic patient?
DeFronzo R, Smith J. Is glucose intolerance harmful for the uremic patient? Kidney International Supplement 1985, 17: s88-97. PMID: 3912590.Peer-Reviewed Original ResearchCitationsImproved Insulin Sensitivity in Patients with Type I Diabetes Mellitus After CSII
Simonson D, Tamborlane W, Sherwin R, Smith J, DeFronzo R, Group T. Improved Insulin Sensitivity in Patients with Type I Diabetes Mellitus After CSII. Diabetes 1985, 34: 80-86. PMID: 3894130, DOI: 10.2337/diab.34.3.s80.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsContinuous subcutaneous insulin infusionGlucose metabolismDiabetic patientsControl subjectsTissue sensitivityAge-matched control subjectsEuglycemic insulin clamp techniqueInsulin-mediated glucose utilizationInsulin clamp techniqueSubcutaneous insulin infusionPlasma glucose concentrationHepatic glucose productionInsulin-stimulated glucose uptakeType IIDDM patientsGlycemic controlInsulin infusionInsulin sensitivityImpaired responseInsulin administrationPeripheral tissuesPatientsClamp techniqueGlucose utilizationMetabolic correctionEffect of insulin on the distribution and disposition of glucose in man.
Ferrannini E, Smith J, Cobelli C, Toffolo G, Pilo A, DeFronzo R. Effect of insulin on the distribution and disposition of glucose in man. Journal Of Clinical Investigation 1985, 76: 357-364. PMID: 3894421, PMCID: PMC423783, DOI: 10.1172/jci111969.Peer-Reviewed Original ResearchCitations
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330 Cedar Street, Ste Suite 114
New Haven, CT 06510
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203.787.0117