1992
Cerebral Lactate Turnover after Electroshock: In vivo Measurements by 1H/13C Magnetic Resonance Spectroscopy
Petroff O, Novotny E, Avison M, Rothman D, Alger J, Ogino T, Shulman G, Prichard J. Cerebral Lactate Turnover after Electroshock: In vivo Measurements by 1H/13C Magnetic Resonance Spectroscopy. Cerebrovascular And Brain Metabolism Reviews 1992, 12: 1022-1029. PMID: 1400641, DOI: 10.1038/jcbfm.1992.139.Peer-Reviewed Original ResearchConceptsBlood lactateLactate poolNuclear magnetic resonance spectroscopyMetabolic stateBrain lactateBlood gasesBlood glucoseElevated lactateMagnetic resonance spectroscopyProlonged elevationRabbit brainPerchloric acid extractsPathological conditionsBrain activationBrainResonance spectroscopyLactate turnoverHigh resolution 1H NMRIntracellular pHElectroshockLactateHuman brainVivo 1HSignificant changesAcid extracts
1990
Direct carbon versus proton heteronuclear editing of 2‐13C ethanol in rabbit brain in vivo: A sensitivity comparison
Novotny E, Ogino T, Rothman D, Petroff O, Prichard J, Shulman R. Direct carbon versus proton heteronuclear editing of 2‐13C ethanol in rabbit brain in vivo: A sensitivity comparison. Magnetic Resonance In Medicine 1990, 16: 431-443. PMID: 2077334, DOI: 10.1002/mrm.1910160310.Peer-Reviewed Original Research13C NMR relaxation times of hepatic glycogen in vitro and in vivo.
Zang L, Laughlin M, Rothman D, Shulman R. 13C NMR relaxation times of hepatic glycogen in vitro and in vivo. Biochemistry 1990, 29: 6815-20. PMID: 2397215, DOI: 10.1021/bi00481a009.Peer-Reviewed Original ResearchProton NMR Observation of Phenylalanine and an Aromatic Metabolite in the Rabbit Brain in Vivo
Avison M, Herschkowitz N, Novotny E, Petroff O, Rothman D, Colombo J, Bachmann C, Shulman R, Prichard J. Proton NMR Observation of Phenylalanine and an Aromatic Metabolite in the Rabbit Brain in Vivo. Pediatric Research 1990, 27: 566-570. PMID: 2162514, DOI: 10.1203/00006450-199006000-00005.Peer-Reviewed Original Research1H NMR visibility of mammalian glycogen in solution.
Zang L, Rothman D, Shulman R. 1H NMR visibility of mammalian glycogen in solution. Proceedings Of The National Academy Of Sciences Of The United States Of America 1990, 87: 1678-1680. PMID: 2308928, PMCID: PMC53545, DOI: 10.1073/pnas.87.5.1678.Peer-Reviewed Original ResearchConceptsHigh molecular weightRapid intramolecular motionsNMR relaxation times T1Chemical shiftsNMR spectraIntramolecular motionsNMR visibilityMolecular weightMammalian glycogenCarbon nucleiRelaxation time T1Rabbit liver glycogenGlycogen contributeTime T1NMRGlycogenMoleculesProtonsExcellent agreementNucleus
1985
Cerebral metabolism in hyper- and hypocarbia: 31P and 1H nuclear magnetic resonance studies.
Petroff O, Prichard J, Behar K, Rothman D, Alger J, Shulman R. Cerebral metabolism in hyper- and hypocarbia: 31P and 1H nuclear magnetic resonance studies. Neurology 1985, 35: 1681-8. PMID: 2933595, DOI: 10.1212/wnl.35.12.1681.Peer-Reviewed Original ResearchApplication of multipulse NMR to observe 13C‐labeled metabolites in biological systems
Bendall M, Hollander J, Arias‐Mendoza F, Rothman D, Behar K, Shulman R. Application of multipulse NMR to observe 13C‐labeled metabolites in biological systems. Magnetic Resonance In Medicine 1985, 2: 56-64. PMID: 3831677, DOI: 10.1002/mrm.1910020107.Peer-Reviewed Original Research
1984
Detection of cerebral lactate in vivo during hypoxemia by 1H NMR at relatively low field strengths (1.9 T).
Behar K, Rothman D, Shulman R, Petroff O, Prichard J. Detection of cerebral lactate in vivo during hypoxemia by 1H NMR at relatively low field strengths (1.9 T). Proceedings Of The National Academy Of Sciences Of The United States Of America 1984, 81: 2517-2519. PMID: 6585812, PMCID: PMC345093, DOI: 10.1073/pnas.81.8.2517.Peer-Reviewed Original Research