2014
Chapter 4.2 Carbon (13C) MRS
Rothman D, De Feyter H. Chapter 4.2 Carbon (13C) MRS. 2014, 312-330. DOI: 10.1016/b978-0-12-401688-0.00023-9.ChaptersNeurotransmitter cyclingHigh neuronal activityHuman brain diseasesOnly noninvasive methodBrain metabolismGlutamate neurotransmissionNeuronal activityMRS studiesPsychiatric diseasesNeuronal functionBrain diseasesBrain functionClinical researchNeuroenergeticsNoninvasive methodDiseaseMRSMRS measurementsHuman researchBrain statesRecent findingsImportant new informationHumansMetabolic pathwaysNeurotransmission
1998
Functional Energy Metabolism:In vivo 13C-NMR Spectroscopy Evidence for Coupling of Cerebral Glucose Consumption and Gl utamatergic Neuronal Activity
Sibson N, Shen J, Mason G, Rothman D, Behar K, Shulman R. Functional Energy Metabolism:In vivo 13C-NMR Spectroscopy Evidence for Coupling of Cerebral Glucose Consumption and Gl utamatergic Neuronal Activity. Developmental Neuroscience 1998, 20: 321-330. PMID: 9778568, DOI: 10.1159/000017327.Peer-Reviewed Original ResearchConceptsRat brain cortexGlucose metabolismBrain cortexNeurotransmitter cyclingTotal glucose oxidationGlutamatergic synaptic activityCerebral glucose consumptionCerebral glucose metabolismFunctional activityFunctional imaging methodsGlucose oxidationOxidative glucose metabolismGlutamate neurotransmitter cyclingSynaptic activityNeuronal activityMild anesthesiaGlutamine synthesisMammalian brainNeurotransmitter releaseGlutamate cyclingEEG activityAmmonia metabolismNeurophysiological basisDetoxification componentsVivo resultsInterpreting functional imaging studies in terms of neurotransmitter cycling
Shulman R, Rothman D. Interpreting functional imaging studies in terms of neurotransmitter cycling. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 11993-11998. PMID: 9751778, PMCID: PMC21753, DOI: 10.1073/pnas.95.20.11993.Peer-Reviewed Original ResearchConceptsFunctional imaging experimentsNeurobiological processesFunctional magnetic resonance imagingBasis of neuroscienceSpecific mental processesFunctional imaging studiesFunctional imaging dataVivo 13C NMR measurementsCognitive psychologyCognitive tasksMental processesPsychological termsPsychological interpretationImaging experimentsNeuroscientific interpretationSensory stimulationPsychological designHuman brainFunctional imaging signalsNeurotransmitter cyclingParticular positron emission tomographyNeurotransmitter fluxBrain energy consumptionImaging studiesImaging data