2024
Brain energy metabolism: A roadmap for future research
Rae C, Baur J, Borges K, Dienel G, Díaz‐García C, Douglass S, Drew K, Duarte J, Duran J, Kann O, Kristian T, Lee‐Liu D, Lindquist B, McNay E, Robinson M, Rothman D, Rowlands B, Ryan T, Scafidi J, Scafidi S, Shuttleworth C, Swanson R, Uruk G, Vardjan N, Zorec R, McKenna M. Brain energy metabolism: A roadmap for future research. Journal Of Neurochemistry 2024, 168: 910-954. PMID: 38183680, PMCID: PMC11102343, DOI: 10.1111/jnc.16032.Peer-Reviewed Original Research
2023
Imaging metabolism of deuterated glucose in patients with primary brain tumors
Corbin Z, Liu Y, Fulbright R, Thaw-Poon S, Baehring J, Blondin N, Kim P, Omuro A, Chiang V, Moliterno J, Omay S, Piepmeier J, Rothman D, de Graaf R, De Feyter H. Imaging metabolism of deuterated glucose in patients with primary brain tumors. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2023 DOI: 10.58530/2023/0142.Peer-Reviewed Original Research
2022
Mechanistic stoichiometric relationship between the rates of neurotransmission and neuronal glucose oxidation: Reevaluation of and alternatives to the pseudo‐malate‐aspartate shuttle model
Rothman D, Behar K, Dienel G. Mechanistic stoichiometric relationship between the rates of neurotransmission and neuronal glucose oxidation: Reevaluation of and alternatives to the pseudo‐malate‐aspartate shuttle model. Journal Of Neurochemistry 2022, 168: 555-591. PMID: 36089566, DOI: 10.1111/jnc.15619.Peer-Reviewed Original ResearchMitochondrial carriersSubcellular compartmentationCultured glutamatergic neuronsMechanistic basisMajor knowledge gapsMechanistic stoichiometryExtracellular GlnGlycolytic metabolismNeuronal compartmentsPre-synaptic structuresGlucose oxidationShuttle modelAlternative mechanismStoichiometric relationshipGlnDiseased brainNeuronal glucose metabolismMetabolismGluAminobutyric acidGlutamatergic neuronsKnowledge gapsCyclingMitochondriaCompartmentation
2004
Summarized Reflections on Metabolism
Shulman R, Rothman D, Schafer J. Summarized Reflections on Metabolism. 2004, 175-184. DOI: 10.1002/0470011505.ch13.Peer-Reviewed Original Research
1998
Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity
Sibson N, Dhankhar A, Mason G, Rothman D, Behar K, Shulman R. Stoichiometric coupling of brain glucose metabolism and glutamatergic neuronal activity. Proceedings Of The National Academy Of Sciences Of The United States Of America 1998, 95: 316-321. PMID: 9419373, PMCID: PMC18211, DOI: 10.1073/pnas.95.1.316.Peer-Reviewed Original ResearchConceptsGlutamatergic neuronal activityGlutamate neurotransmitter cyclingNeuronal activityGln synthesisBrain glucose metabolismSynaptic glutamate releaseGlc metabolismGlutamate releaseRat cortexSynaptic activityGlucose metabolismNeuronal functionBrain activation studiesTricarboxylic acid cycleCortexMetabolismAcid cycleActivation studiesAstrocytesNeuronsActivity