2021
swdpwr: A SAS macro and an R package for power calculations in stepped wedge cluster randomized trials
Chen J, Zhou X, Li F, Spiegelman D. swdpwr: A SAS macro and an R package for power calculations in stepped wedge cluster randomized trials. Computer Methods And Programs In Biomedicine 2021, 213: 106522. PMID: 34818620, PMCID: PMC8665077, DOI: 10.1016/j.cmpb.2021.106522.Peer-Reviewed Original ResearchConceptsWedge clusterIntracluster correlation coefficientContinuous outcomesCross-sectional cohortBinary outcomesExchangeable correlation structureWedge designPublic health intervention evaluationsHealth services researchClosed cohort designPower calculationCohort designClosed cohortStudy designIntracluster correlationIntervention evaluationNeeds of investigatorsOutcomesTrialsCohortServices researchInvestigatorsPrevious studiesSWD
2020
Getting to 90–90–90: Experiences from the MaxART Early Access to ART for All (EAAA) Trial in Eswatini
Walsh F, Khan S, Bärnighausen T, Hettema A, Lejeune C, Mazibuko S, Mlambo CK, Reis R, Fleming Y, Khumalo G, Zwane M, Okello V, Spiegelman D. Getting to 90–90–90: Experiences from the MaxART Early Access to ART for All (EAAA) Trial in Eswatini. Current HIV/AIDS Reports 2020, 17: 324-332. PMID: 32474844, DOI: 10.1007/s11904-020-00501-6.Peer-Reviewed Original ResearchConceptsTreatment guidelinesRoutine viral load monitoringNational HIV careViral load monitoringAdolescent malesSystem-level barriersEarly accessInnovative community-based approachesPublic health systemCommunity outreach strategiesImplementation science researchART initiationHIV careHIV testHIV testingMiddle-income countriesUNAIDS 90Adult menMultiple interventionsHealth systemAdolescent femalesEswatini MinistryTrialsFast trackBaseline dataIntegrating and Interpreting Findings from the Latest Treatment as Prevention Trials
Brault MA, Spiegelman D, Abdool Karim SS, Vermund SH. Integrating and Interpreting Findings from the Latest Treatment as Prevention Trials. Current HIV/AIDS Reports 2020, 17: 249-258. PMID: 32297219, PMCID: PMC7260110, DOI: 10.1007/s11904-020-00492-4.Peer-Reviewed Original ResearchCoaching Intensity, Adherence to Essential Birth Practices, and Health Outcomes in the BetterBirth Trial in Utter Pradesh, India
Barnhart DA, Spiegelman D, Zigler CM, Kara N, Delaney MM, Kalita T, Maji P, Hirschhorn LR, Semrau KEA. Coaching Intensity, Adherence to Essential Birth Practices, and Health Outcomes in the BetterBirth Trial in Utter Pradesh, India. Global Health Science And Practice 2020, 8: ghsp-d-19-00317. PMID: 32127359, PMCID: PMC7108945, DOI: 10.9745/ghsp-d-19-00317.Peer-Reviewed Original ResearchConceptsEssential birth practicesSafe Childbirth ChecklistPerinatal health outcomesBirth attendantsHealth outcomesBetterBirth trialWorld Health Organization Safe Childbirth ChecklistBirth practicesQuality of careSustain behavior changeCoaching-based interventionBehavior changeFrequent coachingPerinatal mortalityBirth facilityAdherenceOutcomesGreater improvementAttendantsVisitsTrialsMonthsRegression modelsAssociationUtter PradeshOptimizing the development and evaluation of complex interventions: lessons learned from the BetterBirth Program and associated trial
Barnhart DA, Semrau KEA, Zigler CM, Molina RL, Delaney MM, Hirschhorn LR, Spiegelman D. Optimizing the development and evaluation of complex interventions: lessons learned from the BetterBirth Program and associated trial. Implementation Science Communications 2020, 1: 29. PMID: 32885188, PMCID: PMC7427863, DOI: 10.1186/s43058-020-00014-8.Peer-Reviewed Original ResearchSafe Childbirth ChecklistComplex intervention developmentComplex interventionsBetterBirth ProgramWorld Health Organization Safe Childbirth ChecklistIntervention developmentIntervention packageEffective intervention componentsReal-world studyFuture complex interventionsNeonatal healthAdvanced stageIntervention componentsComplete data collectionTrialsInterventionHealth impactsImplementation intensityFull-scale trialFuture studiesOutcomesFull-scale evaluationEvaluation
2007
Calcium intake and hip fracture risk in men and women: a meta-analysis of prospective cohort studies and randomized controlled trials 1
Bischoff-Ferrari HA, Dawson-Hughes B, Baron JA, Burckhardt P, Li R, Spiegelman D, Specker B, Orav JE, Wong JB, Staehelin HB, O’Reilly E, Kiel DP, Willett WC. Calcium intake and hip fracture risk in men and women: a meta-analysis of prospective cohort studies and randomized controlled trials 1. American Journal Of Clinical Nutrition 2007, 86: 1780-1790. PMID: 18065599, DOI: 10.1093/ajcn/86.5.1780.Peer-Reviewed Original ResearchConceptsHip fracture riskProspective cohort studyTotal calcium intakeCalcium intakeFracture riskNonvertebral fracturesCohort studyClinical trialsHip fractureCalcium supplementationCa/dPooled RRRandomized trialsSmall trialsIntakeTrialsTrial 1PlaceboWomenRiskMenSupplementationNeutral effectFracturesRRCalcium intake and hip fracture risk in men and women: a meta-analysis of prospective cohort studies and randomized controlled trials
Bischoff-Ferrari H, Dawson-Hughes B, Baron J, Burckhardt P, Li R, Spiegelman D, Specker B, Orav J, Wong J, Staehelin H, O'Reilly E, Kiel D, Willett W. Calcium intake and hip fracture risk in men and women: a meta-analysis of prospective cohort studies and randomized controlled trials. American Journal Of Clinical Nutrition 2007, 86: 1780-1790. DOI: 10.1093/ajcn/86.6.1780.Peer-Reviewed Original Research
2004
Estimating treatment effects in studies of perinatal transmission of HIV
Bang H, Spiegelman D. Estimating treatment effects in studies of perinatal transmission of HIV. Biostatistics 2004, 5: 31-43. PMID: 14744826, DOI: 10.1093/biostatistics/5.1.31.Peer-Reviewed Original Research
2001
HIV-1 LTR Subtype and Perinatal Transmission
Blackard J, Renjifo B, Fawzi W, Hertzmark E, Msamanga G, Mwakagile D, Hunter D, Spiegelman D, Sharghi N, Kagoma C, Essex M. HIV-1 LTR Subtype and Perinatal Transmission. Virology 2001, 287: 261-265. PMID: 11531404, DOI: 10.1006/viro.2001.1059.Peer-Reviewed Original Research
1997
Adverse Outcomes of Underuse of β-Blockers in Elderly Patients-Reply
Soumerai S, McLaughlin T, Spiegelman D, Hertzmark E, Thibault G, Goldman L. Adverse Outcomes of Underuse of β-Blockers in Elderly Patients-Reply. JAMA 1997, 277: 1436-1437. DOI: 10.1001/jama.1997.03540420032022.Peer-Reviewed Original ResearchCalcium channel blockersChannel blockersΒ-blockersNondihydropyridine calcium channel blockersNational evidence-based guidelinesDihydropyridine calcium channel blockerΒ-blocker useAdministrative claims databaseLipid-lowering agentsEvidence-based guidelinesEffective drug classClaims databaseAdverse outcomesDrug classesComparative efficacyBlockersCommunity settingsPatients' repliesAspirinPrevious reportsUnderuseOutcomesPatientsTrials
1994
Human adiposeα-tocopherol andγ-tocopherol kinetics during and after 1 y ofα-tocopherol supplementation
Handelman G, Epstein W, Peerson J, Spiegelman D, Machlin L, Dratz E. Human adiposeα-tocopherol andγ-tocopherol kinetics during and after 1 y ofα-tocopherol supplementation. American Journal Of Clinical Nutrition 1994, 59: 1025-1032. PMID: 8172086, DOI: 10.1093/ajcn/59.5.1025.Peer-Reviewed Original ResearchConceptsAlpha-tocopherol intakeAlpha-tocopherolGamma-tocopherolTocopherol/dLong-term useSupplement useTocopherol ratioNeedle biopsySupplementation periodSupplementation trialTocopherol supplementCross-sectional measurementsHuman AdiposeAdditional yearIntakeSupplementationConsistent decreaseSupplementsSubjectsBiopsyGammaTrials