2020
Impaired Hematological Status Increases the Risk of Mortality among HIV-Infected Adults Initiating Antiretroviral Therapy in Tanzania
Noor RA, Abioye AI, Hertzmark E, Darling AM, Aboud S, Mugusi FM, Sudfeld CR, Spiegelman D, Fawzi WW. Impaired Hematological Status Increases the Risk of Mortality among HIV-Infected Adults Initiating Antiretroviral Therapy in Tanzania. Journal Of Nutrition 2020, 150: 2375-2382. PMID: 32621487, PMCID: PMC7540061, DOI: 10.1093/jn/nxaa172.Peer-Reviewed Original ResearchConceptsRisk of mortalityPrevalence of anemiaHAART initiationHematological statusIron deficiencyAntiretroviral therapySerum ferritinSevere anemiaIncident clinical outcomesRelation of anemiaTrial of multivitaminsActive antiretroviral therapyHIV disease progressionCase-cohort studyIron deficiency anemiaProportional hazards modelElevated ironNonanemic participantsHIV patientsMultivariate adjustmentClinical outcomesMorbidity outcomesAnemia etiologyDeficiency anemiaIron supplementation
2011
Anemia in TB patients predicts recurrence and mortality
Isanaka S, Mugusi F, Urassa W, Bosch R, Villamor E, Spiegelman D, Duggan C, Fawzi W. Anemia in TB patients predicts recurrence and mortality. The FASEB Journal 2011, 25: 779.14-779.14. DOI: 10.1096/fasebj.25.1_supplement.779.14.Peer-Reviewed Original ResearchTreatment failureIron deficiencyHypochromic microcytosisHIV-TB patientsCause of anemiaPoor clinical outcomeRisk of recurrenceMeasures of anemiaTuberculosis recurrenceHIV patientsTB patientsClinical outcomesSevere anemiaRisk factorsAnemiaOverall healthPatientsRecurrenceMortalityRiskMicrocytosisSignificant improvementAssociationDeficiencyFocused management
2010
Lipid-soluble vitamins A, D, and E in HIV-infected pregnant women in Tanzania
Mehta S, Spiegelman D, Aboud S, Giovannucci EL, Msamanga GI, Hertzmark E, Mugusi FM, Hunter DJ, Fawzi WW. Lipid-soluble vitamins A, D, and E in HIV-infected pregnant women in Tanzania. European Journal Of Clinical Nutrition 2010, 64: 808-817. PMID: 20517330, PMCID: PMC3078753, DOI: 10.1038/ejcn.2010.76.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAnemia, Iron-DeficiencyAvitaminosisBlood SedimentationCD8-Positive T-LymphocytesCell CountDietFemaleGestational AgeHemoglobinsHIV InfectionsHumansNutritional StatusPregnancyPrevalenceRegression AnalysisSeleniumTanzaniaVitamin AVitamin A DeficiencyVitamin DVitamin D DeficiencyVitamin EVitamin E DeficiencyYoung AdultConceptsErythrocyte sedimentation rateVitamin E statusPregnant womenLipid-soluble vitaminsVitamin APlasma vitaminGestational ageLow vitaminE statusLow vitamin D statusHigh erythrocyte sedimentation rateLow vitamin E statusLipid-soluble vitamins ACD8 cell countsVitamin D statusHuman immunodeficiency virusPlasma vitamin EPoor nutritional statusPlasma vitamin ALow plasma vitamin AResource-limited settingsD statusLaboratory parametersImmunodeficiency virusSevere anemiaMaternal Vitamin D Status and Child Tuberculosis, Anemia, and Morbidity in Tanzania
Finkelstein J, Mehta S, Manji K, Duggan C, Mugusi F, Spiegelman D, Msamanga G, Fawzi W. Maternal Vitamin D Status and Child Tuberculosis, Anemia, and Morbidity in Tanzania. The FASEB Journal 2010, 24: 227.3-227.3. DOI: 10.1096/fasebj.24.1_supplement.227.3.Peer-Reviewed Original ResearchMaternal vitamin D statusVitamin D statusLow vitamin D statusD statusLow vitamin D levelsPregnant Tanzanian womenTrial of vitaminVitamin D levelsChild health outcomesAssociation of outcomesTimes greater riskProportional hazards modelMonths of ageCD4 countHIV stageChart reviewPulmonary tuberculosisRespiratory symptomsChild tuberculosisSevere anemiaD levelsLowest quintileSecond quintileAnemia outcomesLower risk
2000
Nutritional Factors and Infectious Disease Contribute to Anemia among Pregnant Women with Human Immunodeficiency Virus in Tanzania
Antelman G, Spiegelman D, Narh R, Hunter D, Fawzi W, Msamanga G, Urassa E. Nutritional Factors and Infectious Disease Contribute to Anemia among Pregnant Women with Human Immunodeficiency Virus in Tanzania. Journal Of Nutrition 2000, 130: 1950-1957. PMID: 10917907, DOI: 10.1093/jn/130.8.1950.Peer-Reviewed Original ResearchConceptsBody mass indexHuman immunodeficiency virusSevere anemiaImmunodeficiency virusPregnant womenRetinol levelsRisk factorsPositive pregnant womenMean hemoglobin levelSerum retinol levelsMalaria parasite densitySignificant risk factorsPublic health recommendationsCross-sectional studySignificant independent associationAdverse nutritional consequencesHealth education messagesHIV infectionHemoglobin levelsMass indexVitamin supplementationEarly pregnancyIron supplementationIndependent associationClinical trialsVitamin A supplementation and other predictors of anemia among children from Dar Es Salaam, Tanzania.
Villamor E, Mbise R, Spiegelman D, Ndossi G, Fawzi WW. Vitamin A supplementation and other predictors of anemia among children from Dar Es Salaam, Tanzania. American Journal Of Tropical Medicine And Hygiene 2000, 62: 590-7. PMID: 11289670, DOI: 10.4269/ajtmh.2000.62.590.Peer-Reviewed Original ResearchConceptsSevere anemiaHemoglobin levelsHuman immunodeficiency virus (HIV) infectionPredictors of anemiaPlacebo-controlled trialImmunodeficiency virus infectionMean hemoglobin levelAssociation of hemoglobinMonths of breastfeedingDiagnosis of malariaYears of agePotential confounding variablesMonth old infantsLow socioeconomic statusHIV infectionIndependent determinantsMalaria infectionMaternal levelsAdditional dosesNonsignificant reductionHematologic profileVirus infectionSignificant fallHemoglobin concentrationVitamin A