2005
Plasma Carotenoids, Retinol, and Tocopherols and Risk of Breast Cancer
Tamimi RM, Hankinson SE, Campos H, Spiegelman D, Zhang S, Colditz GA, Willett WC, Hunter DJ. Plasma Carotenoids, Retinol, and Tocopherols and Risk of Breast Cancer. American Journal Of Epidemiology 2005, 161: 153-160. PMID: 15632265, DOI: 10.1093/aje/kwi030.Peer-Reviewed Original ResearchConceptsLutein/zeaxanthinBreast cancerHealth StudyPlasma carotenoidsNurses' Health StudyBreast cancer riskCase-control studyBreast cancer etiologyNodal metastasisHighest quintileInvasive cancerLowest quintileBlood drawInverse associationCancer riskAlpha-tocopherolCancerCancer etiologyGamma-tocopherolWomenRetinolQuintileRiskRole of carotenoidsAssociation
2003
A prospective study of XRCC1 haplotypes and their interaction with plasma carotenoids on breast cancer risk.
Han J, Hankinson SE, De Vivo I, Spiegelman D, Tamimi RM, Mohrenweiser HW, Colditz GA, Hunter DJ. A prospective study of XRCC1 haplotypes and their interaction with plasma carotenoids on breast cancer risk. Cancer Research 2003, 63: 8536-41. PMID: 14679022.Peer-Reviewed Original ResearchConceptsBreast cancer riskBeta-carotene levelsCancer riskInverse associationHealth StudyXRCC1 geneNurses' Health StudyMultivariate odds ratiosCase-control studyPotential protective effectPresent study populationHaplotype-tagging single nucleotide polymorphismsXRCC1 haplotypesCigarette smokingProspective studyCaucasian womenEffect modificationOdds ratioBreast cancerProtective effectStudy populationOxidative DNA damageBreast carcinogenesisGene-environment interactionsPlasma carotenoids
2002
Individual carotenoid concentrations in adipose tissue and plasma as biomarkers of dietary intake 1 , 2 , 3
El-Sohemy A, Baylin A, Kabagambe E, Ascherio A, Spiegelman D, Campos H. Individual carotenoid concentrations in adipose tissue and plasma as biomarkers of dietary intake 1 , 2 , 3. American Journal Of Clinical Nutrition 2002, 76: 172-179. PMID: 12081831, DOI: 10.1093/ajcn/76.1.172.Peer-Reviewed Original ResearchConceptsAdipose tissuePartial Spearman correlation coefficientsFood frequency questionnaireBiomarkers of intakeBody mass indexTotal energy intakeVLDL-cholesterol concentrationsMajor dietary carotenoidsLong-term intakeTissue biopsy samplesIndividual carotenoid concentrationsDietary interviewSpearman correlation coefficientMass indexAdipose tissue biopsy samplesDietary intakePlasma concentrationsCarotenoid intakeBlood samplesBiopsy samplesPlasma carotenoidsTissue carotenoid concentrationsEnergy intakeIntakeDietary carotenoids