2024
Barriers and Facilitators of Implementing a Healthy Lifestyle Intervention at Workplaces in South Africa
Singh S, Naicker A, Grobbelaar H, Singh E, Spiegelman D, Shrestha A. Barriers and Facilitators of Implementing a Healthy Lifestyle Intervention at Workplaces in South Africa. International Journal Of Environmental Research And Public Health 2024, 21: 389. PMID: 38673303, PMCID: PMC11050208, DOI: 10.3390/ijerph21040389.Peer-Reviewed Original ResearchFocus group discussionsHealthy lifestyle interventionIn-depth interviewsLifestyle interventionIntervention programmeDesigning lifestyle interventionsImplement lifestyle interventionsCardiovascular risk factor profileLifestyle intervention programmeImprove health outcomesImplementing health programmesLack of willpowerSemi-structured in-depth interviewsRisk factor profileImplementing intervention programmesFood environmentHealth outcomesImplement interventionsHealth programmesWorkplace stakeholdersWellness programmesWorkplace supportLifestyle choicesFactor profileGroup discussions
2022
Is the Product Method More Efficient Than the Difference Method for Assessing Mediation?
Cheng C, Spiegelman D, Li F. Is the Product Method More Efficient Than the Difference Method for Assessing Mediation? American Journal Of Epidemiology 2022, 192: 84-92. PMID: 35921210, PMCID: PMC10144745, DOI: 10.1093/aje/kwac144.Peer-Reviewed Original Research
2021
Health system gaps in cardiovascular disease prevention and management in Nepal
Shrestha A, Maharjan R, Karmacharya BM, Bajracharya S, Jha N, Shrestha S, Aryal A, Baral PP, Bhatt RD, Bhattarai S, Bista D, Citrin D, Dhimal M, Fitzpatrick AL, Jha AK, Karmacharya RM, Mali S, Neupane T, Oli N, Pandit R, Parajuli SB, Pradhan PMS, Prajapati D, Pyakurel M, Pyakurel P, Rai BK, Sapkota BP, Sapkota S, Shrestha A, Shrestha AP, Shrestha R, Sharma GN, Sharma S, Spiegelman D, Suwal PS, Thapa B, Vaidya A, Xu D, Yan LL, Koju R. Health system gaps in cardiovascular disease prevention and management in Nepal. BMC Health Services Research 2021, 21: 655. PMID: 34225714, PMCID: PMC8258928, DOI: 10.1186/s12913-021-06681-0.Peer-Reviewed Original ResearchConceptsHealth systemCardiovascular disease preventionCause of deathHealth system gapsQuality of careResource-limited settingsNational health policyHealth system performanceBackgroundCardiovascular diseaseCVD preventionCVD careCVD servicesHealth outcomesDisease preventionHealth policyHealth insuranceHealth spendingCarePreventionKey informant interviewsTask ForceSystem gapsInformant interviewsService deliverySafetyReligion, spirituality and diurnal rhythms of salivary cortisol and dehydroepiandrosterone in postmenopausal women
Isehunwa OO, Warner ET, Spiegelman D, Huang T, Tworoger SS, Kent BV, Shields AE. Religion, spirituality and diurnal rhythms of salivary cortisol and dehydroepiandrosterone in postmenopausal women. Comprehensive Psychoneuroendocrinology 2021, 7: 100064. PMID: 34308392, PMCID: PMC8297624, DOI: 10.1016/j.cpnec.2021.100064.Peer-Reviewed Original ResearchCortisol/DHEA ratioHPA axis biomarkersDHEA ratioHigher cortisol/DHEA ratioNurses' Health Study II participantsDiurnal rhythmCross-sectional associationsLate sleep schedulesHigher cortisol levelsPostmenopausal womenAdrenal axisCortisol levelsHealth outcomesPotential covariatesDehydroepiandrosteroneCortisolSalivary cortisolSaliva samplesObserved associationsS measuresWomenExperience scoresAssociationBiomarkersSleep scheduleWorkplace cafeteria and other multicomponent interventions to promote healthy eating among adults: A systematic review
Naicker A, Shrestha A, Joshi C, Willett W, Spiegelman D. Workplace cafeteria and other multicomponent interventions to promote healthy eating among adults: A systematic review. Preventive Medicine Reports 2021, 22: 101333. PMID: 33732606, PMCID: PMC7937753, DOI: 10.1016/j.pmedr.2021.101333.Peer-Reviewed Original ResearchMulticomponent interventionHealthy eatingWorkplace cafeteriasDietary intakeWorkplace health interventionsEnglish-language articlesImproved health outcomesFood choicesHealth risksWeb of ScienceCOM-B systemHealth risk indicatorsVegetable intakeHigh intakeElectronic searchHealth outcomesSystematic reviewHealth interventionsNarrative summaryReview protocolIntakeInterventionCafeteria interventionsRisk indicatorsBehavioral changes
2020
Universal test and treat in relation to HIV disease progression: results from a stepped‐wedge trial in Eswatini
Boeke C, Khan S, Walsh F, Hettema A, Lejeune C, Spiegelman D, Okello V, Harwell J, Mazibuko S, Bärnighausen T. Universal test and treat in relation to HIV disease progression: results from a stepped‐wedge trial in Eswatini. HIV Medicine 2020, 22: 54-59. PMID: 32876360, DOI: 10.1111/hiv.12941.Peer-Reviewed Original ResearchConceptsBody mass indexStepped-wedge trialDisease progressionCD4 countSevere diseaseMultivariate Cox proportional hazards modelWorld Health Organization stageCox proportional hazards modelHIV disease progressionMorbidity/mortalityCells/Proportional hazards modelLower ratesIncident tuberculosisCD4 declineMass indexUniversal testHealth facilitiesBaseline valuesHazards modelHealth outcomesCrowded hospitalsWeight lossProgressionHIVCoaching Intensity, Adherence to Essential Birth Practices, and Health Outcomes in the BetterBirth Trial in Utter Pradesh, India
Barnhart DA, Spiegelman D, Zigler CM, Kara N, Delaney MM, Kalita T, Maji P, Hirschhorn LR, Semrau KEA. Coaching Intensity, Adherence to Essential Birth Practices, and Health Outcomes in the BetterBirth Trial in Utter Pradesh, India. Global Health Science And Practice 2020, 8: ghsp-d-19-00317. PMID: 32127359, PMCID: PMC7108945, DOI: 10.9745/ghsp-d-19-00317.Peer-Reviewed Original ResearchConceptsEssential birth practicesSafe Childbirth ChecklistPerinatal health outcomesBirth attendantsHealth outcomesBetterBirth trialWorld Health Organization Safe Childbirth ChecklistBirth practicesQuality of careSustain behavior changeCoaching-based interventionBehavior changeFrequent coachingPerinatal mortalityBirth facilityAdherenceOutcomesGreater improvementAttendantsVisitsTrialsMonthsRegression modelsAssociationUtter PradeshImpact of the Affordable Care Act on Colorectal Cancer Outcomes: A Systematic Review
Xu MR, Kelly AMB, Kushi LH, Reed ME, Koh HK, Spiegelman D. Impact of the Affordable Care Act on Colorectal Cancer Outcomes: A Systematic Review. American Journal Of Preventive Medicine 2020, 58: 596-603. PMID: 32008799, PMCID: PMC7175922, DOI: 10.1016/j.amepre.2019.11.018.Peer-Reviewed Original ResearchConceptsColorectal cancer screeningAffordable Care ActCancer screeningMedicaid expansionColorectal cancerCare ActNonsignificant increaseColorectal cancer morbidityColorectal cancer outcomesColorectal cancer incidenceStage of diagnosisAffordable Care Act's impactScreening ratesCancer outcomesCancer morbidityPrecancerous lesionsCancer incidenceNonsignificant decreaseEarly diagnosisMortality rateHealth outcomesSystematic reviewHealthcare accessRelevant studiesSignificant decrease
2011
AN APPLICATION OF A RISK SET CALIBRATION METHOD TO A STUDY OF AIR POLLUTION EFFECTS ON ALL CAUSE MORTALITY IN THE NURSES’ HEALTH STUDY
Liao X, Spiegelman D, Hart J, Hong B, Puett R, Suh H, Laden F. AN APPLICATION OF A RISK SET CALIBRATION METHOD TO A STUDY OF AIR POLLUTION EFFECTS ON ALL CAUSE MORTALITY IN THE NURSES’ HEALTH STUDY. ISEE Conference Abstracts 2011, 2011 DOI: 10.1289/isee.2011.00990.Peer-Reviewed Original ResearchCause mortalityRelative riskHealth StudyChronic exposureChronic PM2.5 exposureNurses' Health StudyIndividual exposure levelsAverage of PM2.5Risk factorsExposure measurement errorState of residenceEstimates of riskParticipants' residencesPM2.5 exposureHealth outcomesMortalityMonthly exposureExposure levelsPersonal exposureExposure monitoringRiskCalendar yearAir pollution effectsExposureMidwestern metropolitan area
2007
Regression calibration for logistic regression with multiple surrogates for one exposure
Weller E, Milton D, Eisen E, Spiegelman D. Regression calibration for logistic regression with multiple surrogates for one exposure. Journal Of Statistical Planning And Inference 2007, 137: 449-461. DOI: 10.1016/j.jspi.2006.01.009.Peer-Reviewed Original ResearchCross-sectional epidemiologic studyExposure measurementsExposure-response associationsQuantitative exposure measurementsLung functionBaseline prevalenceExposure measurement errorOccupational exposureEpidemiologic studiesFluid exposureHealth outcomesExposure assessment studiesLogistic regressionIndividual exposurePersonal monitors
2005
Selenium levels in relation to morbidity and mortality among children born to HIV-infected mothers
Kupka R, Msamanga GI, Spiegelman D, Rifai N, Hunter DJ, Fawzi WW. Selenium levels in relation to morbidity and mortality among children born to HIV-infected mothers. European Journal Of Clinical Nutrition 2005, 59: 1250-1258. PMID: 16015252, DOI: 10.1038/sj.ejcn.1602236.Peer-Reviewed Original ResearchConceptsPlasma selenium levelsMorbidity informationSelenium levelsChild mortalityMaternal vitamin supplementsMonthly clinic visitsProspective cohort studyTertiary care hospitalMuhimbili National HospitalRisk of diarrheaChild health outcomesMonths of ageSelenium statusCause mortalityClinic visitsCohort studyRespiratory outcomesMedian ageStudy clinicNational HospitalVitamin supplementsHealth outcomesStudy childrenFogarty International CenterStudy participants
2003
Occupational exposure to methyl tertiary butyl ether in relation to key health symptom prevalence: the effect of measurement error correction
Keshaviah A, Weller E, Spiegelman D. Occupational exposure to methyl tertiary butyl ether in relation to key health symptom prevalence: the effect of measurement error correction. Environmetrics 2003, 14: 573-582. DOI: 10.1002/env.604.Peer-Reviewed Original ResearchEffect of MTBEHealth symptomsStudy participantsJob categoriesSmoking statusSerum concentrationsBlood concentrationsHealth outcomesMTBE exposureEye irritationSignificant associationSymptomsMethyl tertiary butyl etherAvailable dataPrevalenceExposureExposure effectsParticipantsLow levelsHeadacheRegression calibration methodIrritation
1997
Statistical issues in assessing human population exposures
Weller E, Ryan L, Spiegelman D, Smith T. Statistical issues in assessing human population exposures. Chemometrics And Intelligent Laboratory Systems 1997, 37: 189-195. DOI: 10.1016/s0169-7439(97)00003-8.Peer-Reviewed Original ResearchDose-response relationshipStatistical issuesExposure-dose relationshipsMeasurement error problemsPrimary scientific interestHealth effectsStatistical aspectsStatistical methodsEnvironmental epidemiology studiesHealth outcomesEpidemiology studiesHuman population exposureExposure levelsMeasurement errorExposure assessmentError problemDirect applicationWelding fumesLoss of efficiencyExposureOutcomesPopulation exposureDose
1996
Self-Reported Birthweight and History of Having Been Breastfed among Younger Women: An Assessment of Validity
TROY L, MICHELS K, HUNTER D, SPIEGELMAN D, MANSON J, COLDITZ G, STAMPFER M, WILLETT W. Self-Reported Birthweight and History of Having Been Breastfed among Younger Women: An Assessment of Validity. International Journal Of Epidemiology 1996, 25: 122-127. PMID: 8666479, DOI: 10.1093/ije/25.1.122.Peer-Reviewed Original ResearchConceptsSelf-reported birthweightState birth recordsSelf-reported historyCohort participantsBirth recordsDuration of breastfeedingMiddle-aged womenYears of ageDistribution of birthweightsAssessment of validityParticipants' self-reported historyBreastfeeding historyNHSII participantsBirthweightHealth outcomesPotential associationYoung womenSpearman correlationFeeding historyRecent evidenceMothersWomenMothers' reportsReportDaughters' reports