2012
Elevated alanine aminotransferase in antiretroviral‐naïve HIV‐infected African patients: magnitude and risk factors
Nagu T, Kanyangarara M, Hawkins C, Hertmark E, Chalamila G, Spiegelman D, Mugusi F, Fawzi W. Elevated alanine aminotransferase in antiretroviral‐naïve HIV‐infected African patients: magnitude and risk factors. HIV Medicine 2012, 13: 541-548. PMID: 22416813, PMCID: PMC3391335, DOI: 10.1111/j.1468-1293.2012.01006.x.Peer-Reviewed Original ResearchConceptsElevated alanine aminotransferaseIU/LAlanine aminotransferaseAntiretroviral therapyHigh riskWorld Health Organization clinical stageCD4 T-lymphocyte countFirst-line antiretroviral therapyHepatitis B virus coinfectionALT measurementsLow-density lipoprotein cholesterolLog-binomial regression modelsB virus coinfectionT-lymphocyte countsART-naïve HIVCells/μLHepatotoxic side effectsCurrent tuberculosis (TB) treatmentResource-limited settingsCross-sectional analysisAdvanced immunosuppressionHBV coinfectionART-naïveHIV careLipoprotein cholesterol
2003
Use of Complementary and Alternative Therapies by Patients With Human Immunodeficiency Virus Disease in the Era of Highly Active Antiretroviral Therapy
Bica I, Tang AM, Skinner S, Spiegelman D, Knox T, Gorbach S, Wilson IB. Use of Complementary and Alternative Therapies by Patients With Human Immunodeficiency Virus Disease in the Era of Highly Active Antiretroviral Therapy. Journal Of Alternative And Complementary Medicine 2003, 9: 65-76. PMID: 12676036, DOI: 10.1089/107555303321222955.Peer-Reviewed Original ResearchConceptsHuman immunodeficiency virusActive antiretroviral therapyCAM useAntiretroviral therapyHighly Active Antiretroviral TherapyHuman immunodeficiency virus (HIV) diseaseCAM therapy useHealthy Living StudyPotential drug interactionsUse of ComplementaryLow-risk groupAlternative medical therapiesEffective drug treatmentCross-sectional analysisLeast high schoolHAART useCohort studyMale patientsMedical therapyTherapy useImmunodeficiency virusComplementary therapiesAlternative therapiesStudy visitRisk groups
2001
Assessment of Questionnaire Validity for Measuring Total Fat Intake using Plasma Lipid Levels as Criteria
Willett W, Stampfer M, Chu NF, Spiegelman D, Holmes M, Rimm E. Assessment of Questionnaire Validity for Measuring Total Fat Intake using Plasma Lipid Levels as Criteria. American Journal Of Epidemiology 2001, 154: 1107-1112. PMID: 11744515, DOI: 10.1093/aje/154.12.1107.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBiomarkersBody Mass IndexBody WeightCholesterol, HDLCohort StudiesCross-Sectional StudiesDiet SurveysDietary FatsDietary FiberDietary ProteinsEnergy IntakeExerciseFastingFollow-Up StudiesHumansMaleMiddle AgedProspective StudiesRegression AnalysisReproducibility of ResultsSmokingSurveys and QuestionnairesTriglyceridesConceptsTotal fat intakeFood frequency questionnaireFat intakeTriglyceride levelsFrequency questionnaireDietary fatSemiquantitative food frequency questionnaireHealth Professionals FollowBody mass indexHigh fat intakePlasma lipid levelsMetabolic studiesIntake of proteinCross-sectional analysisProfessionals FollowOverweight menMass indexInverse associationLipid levelsPhysical activityBlood specimensAlcohol consumptionSpecific biomarkersIntakeMultiple regression analysisWeight and body composition in a cohort of HIV-positive men and women
Forrester J, Spiegelman D, Woods M, Knox T, Fauntleroy J, Gorbach S. Weight and body composition in a cohort of HIV-positive men and women. Public Health Nutrition 2001, 4: 743-747. PMID: 11415480, DOI: 10.1079/phn200099.Peer-Reviewed Original Research
2000
Body Composition and Dietary Intake in Relation to Drug Abuse in a Cohort of HIV-Positive Persons
Forrester J, Woods M, Knox T, Spiegelman D, Skinner S, Gorbach S. Body Composition and Dietary Intake in Relation to Drug Abuse in a Cohort of HIV-Positive Persons. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2000, 25: s43-s48. PMID: 11126426, DOI: 10.1097/00042560-200010001-00007.Peer-Reviewed Original ResearchConceptsBody mass indexIntravenous drug usersBody compositionDrug usersEnergy intakeDietary intakeFat massCurrent intravenous drug usersPast intravenous drug usersDrug abuseSelf-reported energy intakeHIV-positive personsHigher energy intakeBioelectrical impedance analysisCross-sectional analysisDrug use categoriesDrug use groupHIV infectionMass indexFood recordsDietary dataNonintravenous drugsNutritional statusIntakeWomenBody Composition and Dietary Intake in Relation to Drug Abuse in a Cohort of HIV-Positive Persons
Forrester J, Woods M, Knox T, Spiegelman D, Skinner S, Gorbach S. Body Composition and Dietary Intake in Relation to Drug Abuse in a Cohort of HIV-Positive Persons. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2000, 25: s43-s48. DOI: 10.1097/00126334-200010001-00007.Peer-Reviewed Original ResearchBody mass indexIntravenous drug usersBody compositionDrug usersEnergy intakeDietary intakeFat massCurrent intravenous drug usersPast intravenous drug usersDrug abuseSelf-reported energy intakeHIV-positive personsHigher energy intakeBioelectrical impedance analysisCross-sectional analysisDrug use categoriesDrug use groupHIV infectionMass indexFood recordsDietary dataNonintravenous drugsNutritional statusIntakeWomenRelation of lean body mass to health-related quality of life in persons with HIV.
Wilson I, Roubenoff R, Knox T, Spiegelman D, Gorbach S. Relation of lean body mass to health-related quality of life in persons with HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2000, 24: 137-46. PMID: 10935689, DOI: 10.1097/00126334-200006010-00008.Peer-Reviewed Original ResearchConceptsGeneral health perceptionPhysical functionHealth-related qualityLean body massHigher lean body massHealth perceptionAssociated with better physical functionClinical impact of interventionsHealth-related quality of lifeDiverse population of personsBioimpedance analysisPatient self-reportBody massImpact of interventionsPopulation of personsCross-sectional analysisQuality of lifeIncreased LBMSelf-reportDiverse populationsEnergy/fatigueMultivariate modelHIVCD4 countHIV infectionRelation of Lean Body Mass to Health-Related Quality of Life in Persons With HIV
Wilson I, Roubenoff R, Knox T, Spiegelman D, Gorbach S. Relation of Lean Body Mass to Health-Related Quality of Life in Persons With HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2000, 24: 137-146. DOI: 10.1097/00042560-200006010-00008.Peer-Reviewed Original ResearchConceptsLean body massHigher lean body massGeneral health perceptionEnergy/fatiguePhysical functioningHealth perceptionBetter general health perceptionBioimpedance analysisDesign Cross-sectional analysisMeasures of HRQLHealth-related qualityBody massLast monthBetter physical functioningQuality of lifeCross-sectional analysisCD4 countHIV infectionMean ageClinical impactMultivariable modelHIVCells/Number of daysWomenRelation of Lean Body Mass to Health-Related Quality of Life in Persons With HIV
Wilson I, Roubenoff R, Knox T, Spiegelman D, Gorbach S. Relation of Lean Body Mass to Health-Related Quality of Life in Persons With HIV. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2000, 24: 137-146. DOI: 10.1097/00126334-200006010-00007.Peer-Reviewed Original ResearchLean body massHigher lean body massGeneral health perceptionEnergy/fatiguePhysical functioningHealth perceptionBetter general health perceptionBioimpedance analysisMeasures of HRQLHealth-related qualityBody massLast monthBetter physical functioningQuality of lifeCross-sectional analysisCD4 countHIV infectionMean ageClinical impactMultivariable modelHIVCells/Number of daysWomenMen
1999
Elevated resting energy expenditure among HIV-seropositive persons receiving highly active antiretroviral therapy
Shevitz A, Knox T, Spiegelman D, Roubenoff R, Gorbach S, Skolnik P. Elevated resting energy expenditure among HIV-seropositive persons receiving highly active antiretroviral therapy. AIDS 1999, 13: 1351-1357. PMID: 10449288, DOI: 10.1097/00002030-199907300-00012.Peer-Reviewed Original ResearchConceptsFat-free massActive antiretroviral therapyHAART useHIV RNAAntiretroviral therapyCohort studyViral burdenKJ/dayHIV-seropositive menCD4 cell countHIV-seropositive personsLog10 copies/Energy expenditureLarge cohort studyIndependent effectsCross-sectional analysisHIV diseaseMedication regimensViral loadCopies/Adjusted REECell countElevated REEViral replicationHAARTDistribution of and Factors Associated With Serum Homocysteine Levels in Children: Child and Adolescent Trial for Cardiovascular Health
Osganian SK, Stampfer MJ, Spiegelman D, Rimm E, Cutler JA, Feldman HA, Montgomery DH, Webber LS, Lytle LA, Bausserman L, Nader PR. Distribution of and Factors Associated With Serum Homocysteine Levels in Children: Child and Adolescent Trial for Cardiovascular Health. JAMA 1999, 281: 1189-1196. PMID: 10199428, DOI: 10.1001/jama.281.13.1189.Peer-Reviewed Original ResearchConceptsSerum folic acidSystolic blood pressureHomocysteine levelsHomocysteine concentrationsCardiovascular diseaseSerum homocysteineAdolescent TrialBlood pressureSerum levelsFolic acidCardiovascular healthSerum total homocysteine concentrationsVitamin B12Mean homocysteine concentrationFuture cardiovascular diseaseVitamin B12 levelsSerum homocysteine concentrationsSchool-based cohortSerum homocysteine levelsTotal homocysteine concentrationsSerum lipid levelsBody mass indexCross-sectional analysisNonusers of multivitaminsB12 levels