2018
PET imaging reveals lower kappa opioid receptor availability in alcoholics but no effect of age
Vijay A, Cavallo D, Goldberg A, de Laat B, Nabulsi N, Huang Y, Krishnan-Sarin S, Morris ED. PET imaging reveals lower kappa opioid receptor availability in alcoholics but no effect of age. Neuropsychopharmacology 2018, 43: 2539-2547. PMID: 30188515, PMCID: PMC6224533, DOI: 10.1038/s41386-018-0199-1.Peer-Reviewed Original ResearchConceptsHealthy control cohortVolume of distributionOpioid receptor systemKappa-opioid receptorsOpioid receptorsDelta opioid receptor systemReceptor systemMu-opioid receptor systemOpioid receptor availabilityPotential pharmacological targetEffect of ageAge-related declineControl cohortPET scansAntagonist tracersReceptor availabilityMultivariate analysisPharmacological targetsPET imagingReceptorsAgePartial volume correctionCohortVT valuesPresent studyPreferring more e-cigarette flavors is associated with e-cigarette use frequency among adolescents but not adults
Morean ME, Butler ER, Bold KW, Kong G, Camenga DR, Cavallo DA, Simon P, O’Malley S, Krishnan-Sarin S. Preferring more e-cigarette flavors is associated with e-cigarette use frequency among adolescents but not adults. PLOS ONE 2018, 13: e0189015. PMID: 29300749, PMCID: PMC5754053, DOI: 10.1371/journal.pone.0189015.Peer-Reviewed Original ResearchConceptsE-cigarette useE-cigarette usersPast-month e-cigarette usersE-cigarette use frequencyE-cigarette flavorsE-liquidsMore daysFrequent e-cigarette useSchool-based surveyTotal numberFlavor preferencesAdult e-cigarette usersAdolescent e-cigarette useE-cigarettesUse frequencyAnalytic sampleAdultsSample of adolescentsAdolescentsGreater total numberLiquid flavorsConnecticut high schoolsAdult samplesLarge proportionDays
2016
Current and Former Smokers’ Use of Electronic Cigarettes for Quitting Smoking: An Exploratory Study of Adolescents and Young Adults
Camenga DR, Kong G, Cavallo DA, Krishnan-Sarin S. Current and Former Smokers’ Use of Electronic Cigarettes for Quitting Smoking: An Exploratory Study of Adolescents and Young Adults. Nicotine & Tobacco Research 2016, 19: 1531-1535. PMID: 27663781, PMCID: PMC5896554, DOI: 10.1093/ntr/ntw248.Peer-Reviewed Original ResearchConceptsE-cigarette useFrequent e-cigarette useE-cigarettesSmokers' useSmoking cessationYoung adultsMore frequent e-cigarette useElectronic cigarettesSmoking cessation medicationsCigarette smoking statusE-cigarette use patternsSmoking medicationsCessation medicationsFormer smokersCurrent smokersSmoking statusComparative safetyQuitting smokingTobacco abstinenceWhite raceAdjusted modelPerceptions of harmfulnessE-cigarette flavorsSmokersSmoking
2015
N‐Methyl‐d‐Aspartate Receptor Antagonism has Differential Effects on Alcohol Craving and Drinking in Heavy Drinkers
Krishnan‐Sarin S, O'Malley SS, Franco N, Cavallo DA, Morean M, Shi J, Pittman B, Krystal JH. N‐Methyl‐d‐Aspartate Receptor Antagonism has Differential Effects on Alcohol Craving and Drinking in Heavy Drinkers. Alcohol Clinical And Experimental Research 2015, 39: 300-307. PMID: 25664775, PMCID: PMC4331214, DOI: 10.1111/acer.12619.Peer-Reviewed Original ResearchConceptsAlcohol drinkingFamily historyHeavy drinkersAlcohol cravingN-methyl-D-aspartate receptor antagonistN-methyl-D-aspartate receptor antagonismAlcohol cue-induced cravingEffects of FHHigher baseline levelsPresence of impulsivityAlcohol use disorderCue-induced cravingAlcohol-induced stimulationReceptor antagonismReceptor antagonistPriming doseNMDA receptorsUse disordersMemantineBaseline levelsModulatory influencePotential efficacyAlcohol accessDrinkersEighth day
2014
Reasons for Electronic Cigarette Experimentation and Discontinuation Among Adolescents and Young Adults
Kong G, Morean ME, Cavallo DA, Camenga DR, Krishnan-Sarin S. Reasons for Electronic Cigarette Experimentation and Discontinuation Among Adolescents and Young Adults. Nicotine & Tobacco Research 2014, 17: 847-854. PMID: 25481917, PMCID: PMC4674436, DOI: 10.1093/ntr/ntu257.Peer-Reviewed Original ResearchConceptsE-cigarette experimentationE-cigarettesCigarette smoking statusElectronic cigarette useTop reasonsSmoking statusCigarette smokersE-cigarette flavorsFocus groupsDiscontinuationCigarette useCigarette experimentationHealth concernPrevention effortsYoung adultsHealth risksSmokersSmokingGroupCigarettesYoung people
2013
Pubertal Status, Sensation-Seeking, Impulsivity, and Substance Use in High School–Aged Boys and Girls
Kong G, Smith AE, McMahon TJ, Cavallo DA, Schepis TS, Desai RA, Potenza MN, Krishnan-Sarin S. Pubertal Status, Sensation-Seeking, Impulsivity, and Substance Use in High School–Aged Boys and Girls. Journal Of Addiction Medicine 2013, 7: 116-121. PMID: 23370933, PMCID: PMC3618523, DOI: 10.1097/adm.0b013e31828230ca.Peer-Reviewed Original Research
2008
Contingency management for smoking cessation: enhancing feasibility through use of immunoassay test strips measuring cotinine.
Schepis TS, Duhig AM, Liss T, McFetridge A, Wu R, Cavallo DA, Dahl T, Jatlow P, Krishnan-Sarin S. Contingency management for smoking cessation: enhancing feasibility through use of immunoassay test strips measuring cotinine. Nicotine & Tobacco Research 2008, 10: 1495-501. PMID: 19023841, PMCID: PMC3679884, DOI: 10.1080/14622200802323209.Peer-Reviewed Original ResearchConceptsContingency managementAdolescent smokersTreatment-seeking adultsQuit attemptsSmoking cessationUse of cotinineUrinary cotinineBehavioral interventionsIntervention programsImmunoassay test stripUrinary cotinine levelsAbstinenceMultiple daily measurementsObjective indicatorsDaily appointmentsCotinine levelsCotinineImmunoassay testingGood markerAdultsBreath COVariety of substancesInterventionCessationSmokers
2007
Enhancing brief cognitive-behavioral therapy with motivational enhancement techniques in cocaine users
McKee SA, Carroll KM, Sinha R, Robinson JE, Nich C, Cavallo D, O’Malley S. Enhancing brief cognitive-behavioral therapy with motivational enhancement techniques in cocaine users. Drug And Alcohol Dependence 2007, 91: 97-101. PMID: 17573205, PMCID: PMC2386854, DOI: 10.1016/j.drugalcdep.2007.05.006.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyMotivational enhancement therapyBrief cognitive behavioral therapyMotivational enhancement techniquesSpecific treatment componentsCocaine usersExpectations of successMotivational interviewing techniquesCBT conditionCocaine useEnhancement therapyTreatment componentsIntervention paradigmInterviewing techniquesTherapy processMixed supportCocaine abuseInitial sessionTreatment retentionThree-sessionGreater desireGreat difficultyTreatment conditionsTreatment sessionsProcess measures