2018
Management of metastatic melanoma: improved survival in a national cohort following the approvals of checkpoint blockade immunotherapies and targeted therapies
Dobry AS, Zogg CK, Hodi FS, Smith TR, Ott PA, Iorgulescu JB. Management of metastatic melanoma: improved survival in a national cohort following the approvals of checkpoint blockade immunotherapies and targeted therapies. Cancer Immunology, Immunotherapy 2018, 67: 1833-1844. PMID: 30191256, PMCID: PMC6249064, DOI: 10.1007/s00262-018-2241-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntineoplastic Agents, ImmunologicalComorbidityDisease ManagementFemaleHealth Care SurveysHumansImmunotherapyMaleMelanomaMiddle AgedMolecular Targeted TherapyNeoplasm StagingOdds RatioProtein Kinase InhibitorsProto-Oncogene Proteins B-rafRegistriesSymptom AssessmentUnited StatesYoung AdultConceptsStage 4 melanomaOverall survivalInitial approvalCutaneous melanomaLandmark survival analysisSubstantial clinical efficacyImproved overall survivalMetastatic cutaneous melanomaNational Cancer DatabaseStage 4 diseaseCheckpoint blockade immunotherapySurvival of patientsRisk-adjusted analysisBlockade immunotherapyCheckpoint blockadeNovel immunotherapiesMultivariable analysisClinical efficacyMetastatic melanomaNational cohortCancer DatabaseUninsured patientsClinical trialsPatientsSurvival analysisAdjuvant Chemotherapy Is Associated With Improved Survival for Late‐Stage Salivary Squamous Cell Carcinoma
Cheraghlou S, Schettino A, Zogg CK, Otremba MD, Bhatia A, Park HS, Osborn HA, Mehra S, Yarbrough WG, Judson BL. Adjuvant Chemotherapy Is Associated With Improved Survival for Late‐Stage Salivary Squamous Cell Carcinoma. The Laryngoscope 2018, 129: 883-889. PMID: 30151947, DOI: 10.1002/lary.27444.Peer-Reviewed Original ResearchMeSH KeywordsAgedCarcinoma, Squamous CellChemoradiotherapy, AdjuvantChemotherapy, AdjuvantCombined Modality TherapyFemaleHumansKaplan-Meier EstimateMaleMiddle AgedNeoplasm StagingPropensity ScoreProportional Hazards ModelsRadiotherapy, AdjuvantRetrospective StudiesSalivary Gland NeoplasmsSurvival RateTreatment OutcomeConceptsLate-stage patientsSquamous cell carcinomaAdjuvant radiotherapyAdjuvant therapyAdjuvant chemoradiotherapyAdjuvant chemotherapyImproved survivalCell carcinomaImproved long-term survivalCox survival regressionPrimary cutaneous malignanciesUnique disease entityAddition of chemotherapyNational Cancer DatabaseEarly-stage diseaseFive-year survivalEarly-stage patientsKaplan-Meier analysisParotid gland cancerLate stage groupLong-term survivalSurvival benefitCutaneous malignanciesPoor prognosisRetrospective study
2017
Treatment deintensification in human papillomavirus‐positive oropharynx cancer: Outcomes from the National Cancer Data Base
Cheraghlou S, Yu PK, Otremba MD, Park HS, Bhatia A, Zogg CK, Mehra S, Yarbrough WG, Judson BL. Treatment deintensification in human papillomavirus‐positive oropharynx cancer: Outcomes from the National Cancer Data Base. Cancer 2017, 124: 717-726. PMID: 29243245, DOI: 10.1002/cncr.31104.Peer-Reviewed Original ResearchConceptsNational Cancer Data BaseStage III diseaseTriple-modality therapyAdjuvant radiotherapyOropharyngeal cancerStage IHuman papillomavirus-positive oropharyngeal cancerUnivariate Kaplan-Meier analysisAvoidance of chemotherapyDeintensification of treatmentEdition stage IStage II diseaseMultivariate Cox regressionAmerican Joint CommitteeKaplan-Meier analysisDisease stage groupsForm of treatmentTreatment deintensificationAdjuvant chemoradiotherapyDefinitive radiotherapyTreatment intensificationFavorable prognosisImproved survivalCox regressionRetrospective studyEpidemiology of malignant cutaneous granular cell tumors: A US population-based cohort analysis using the Surveillance, Epidemiology, and End Results (SEER) database
Mirza FN, Tuggle CT, Zogg CK, Mirza HN, Narayan D. Epidemiology of malignant cutaneous granular cell tumors: A US population-based cohort analysis using the Surveillance, Epidemiology, and End Results (SEER) database. Journal Of The American Academy Of Dermatology 2017, 78: 490-497.e1. PMID: 28989104, PMCID: PMC5815907, DOI: 10.1016/j.jaad.2017.09.062.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBlack or African AmericanChildFemaleGranular Cell TumorHumansIncidenceKaplan-Meier EstimateKidney NeoplasmsMaleMiddle AgedNeoplasm StagingPancreatic NeoplasmsResidence CharacteristicsRetrospective StudiesSEER ProgramSex FactorsSkin NeoplasmsSurvival RateUnited StatesWhite PeopleYoung AdultConceptsDisease-specific survivalCutaneous granular cell tumorsPopulation-based cohort analysisEnd Results (SEER) databaseMedian survival timeGranular cell tumorSurgical resectionResults databaseCell tumorsCohort analysisSurvival timeCox proportional hazards regressionPoor disease-specific survivalRisk-adjusted associationHigh-risk patientsEnd Results (SEER) dataProportional hazards regressionSingle-institution studyAdvanced cancer stageRisk-adjusted modelsDSS ratesOverall survivalPatient characteristicsSubstantial morbiditySecondary malignancies
2015
Financial Impact of Postoperative Complication Following Hepato-Pancreatico-Biliary Surgery for Cancer
Gani F, Hundt J, Makary MA, Haider AH, Zogg CK, Pawlik TM. Financial Impact of Postoperative Complication Following Hepato-Pancreatico-Biliary Surgery for Cancer. Annals Of Surgical Oncology 2015, 23: 1064-1070. PMID: 26714947, DOI: 10.1245/s10434-015-5042-x.Peer-Reviewed Original ResearchConceptsPostoperative complications