2022
National outcomes following benign cardiac tumor resection: A critical sex‐based disparity
Newell P, Zogg CK, Kusner J, Hirji S, Kerolos M, Kaneko T. National outcomes following benign cardiac tumor resection: A critical sex‐based disparity. Journal Of Cardiac Surgery 2022, 37: 2653-2660. PMID: 35662249, DOI: 10.1111/jocs.16654.Peer-Reviewed Original ResearchMeSH KeywordsComorbidityDatabases, FactualFemaleHeart NeoplasmsHumansMaleMiddle AgedPatient ReadmissionRisk FactorsConceptsComposite morbiditySurgical resectionIndependent predictorsMultivariable analysisVentricular tumorsFemale sexBenign primary cardiac tumorsCardiac tumor resectionLower comorbidity burdenPrimary cardiac tumorsNationwide Readmissions DatabaseMajority of patientsIntra-atrial septumNational outcomesSex-based disparitiesComorbidity burdenCardiac tumorsPrimary outcomeFemale patientsMean ageVentricular septumPrimary diagnosisRight atriumTumor locationTumor resection
2020
Epidemiology, treatment, survival, and prognostic factors of cutaneous mucoepidermoid carcinoma: A distinct entity with an indolent clinical course
Mirza FN, Yumeen S, Zogg CK, Mirza HN, Leventhal JS. Epidemiology, treatment, survival, and prognostic factors of cutaneous mucoepidermoid carcinoma: A distinct entity with an indolent clinical course. Journal Of The American Academy Of Dermatology 2020, 83: 1827-1830. PMID: 32446830, PMCID: PMC7669598, DOI: 10.1016/j.jaad.2020.05.086.Peer-Reviewed Original ResearchThirty- and 90-Day Readmissions After Treatment of Traumatic Subdural Hematoma: National Trend Analysis
Koo AB, Elsamadicy AA, David WB, Zogg CK, Santarosa C, Sujijantarat N, Robert SM, Kundishora AJ, Cord BJ, Hebert R, Bahrassa F, Malhotra A, Matouk CC. Thirty- and 90-Day Readmissions After Treatment of Traumatic Subdural Hematoma: National Trend Analysis. World Neurosurgery 2020, 139: e212-e219. PMID: 32272271, PMCID: PMC7380544, DOI: 10.1016/j.wneu.2020.03.168.Peer-Reviewed Original ResearchConceptsTraumatic subdural hematomaSubdural hematomaRheumatoid arthritis/collagen vascular diseasesMultivariate logistic regression analysisCollagen vascular diseaseNationwide Readmissions DatabaseCongestive heart failureLikelihood of readmissionPrimary procedure codeTraumatic brain injuryLogistic regression analysisReadmission ratesRenal failureHeart failurePostoperative infectionNinth RevisionSurgical interventionPatient populationVascular diseaseCerebral meningesBrain injuryClinical ModificationPatient managementReadmissionInternational ClassificationUnderweight patients are at just as much risk as super morbidly obese patients when undergoing anterior cervical spine surgery
Ottesen TD, Malpani R, Galivanche AR, Zogg CK, Varthi AG, Grauer JN. Underweight patients are at just as much risk as super morbidly obese patients when undergoing anterior cervical spine surgery. The Spine Journal 2020, 20: 1085-1095. PMID: 32194246, PMCID: PMC7380546, DOI: 10.1016/j.spinee.2020.03.007.Peer-Reviewed Original ResearchConceptsAnterior cervical spine surgeryBody mass indexCervical spine surgeryNational Surgical Quality Improvement Program databaseSuper morbidly obese patientsQuality Improvement Program databaseWorld Health Organization categoriesMorbidly obese patientsImprovement Program databaseObese patientsAdverse eventsAdverse outcomesSpine surgeryUnderweight patientsPostoperative infectionProgram databaseSurgeons National Surgical Quality Improvement Program databaseMultivariate analysisAnterior cervical spine proceduresOverweight/obese categoriesThirty-day adverse eventsHigher body mass indexLower body mass indexAdverse outcome categoriesNormal BMI patientsRisk Factors Portending Extended Length of Stay After Suboccipital Decompression for Adult Chiari I Malformation
Elsamadicy AA, Koo AB, Lee M, David WB, Kundishora AJ, Freedman IG, Zogg CK, Hong CS, DeSpenza T, Sarkozy M, Kahle KT, DiLuna M. Risk Factors Portending Extended Length of Stay After Suboccipital Decompression for Adult Chiari I Malformation. World Neurosurgery 2020, 138: e515-e522. PMID: 32147550, PMCID: PMC7379177, DOI: 10.1016/j.wneu.2020.02.158.Peer-Reviewed Original ResearchConceptsPatient-level factorsMultivariate logistic regressionExtended LOSLOS cohortSurgical decompressionDecompression surgeryOdds ratioGreater overall complication ratesMultiple patient-level factorsLogistic regressionChiari malformation type IAdult Chiari I malformationPatient's baseline comorbidityOverall complication rateRetrospective cohort studyChiari I malformationRisk-adjusted LOSPostoperative complicationsAdult patientsCohort studyComplication ratePatient demographicsSuboccipital decompressionElectrolyte disordersObstructive hydrocephalusThirty-Day Nonindex Readmissions and Clinical Outcomes After Cardiac Surgery
Hirji SA, Percy ED, Zogg CK, Vaduganathan M, Kiehm S, Pelletier M, Kaneko T. Thirty-Day Nonindex Readmissions and Clinical Outcomes After Cardiac Surgery. The Annals Of Thoracic Surgery 2020, 110: 484-491. PMID: 31972128, PMCID: PMC7382395, DOI: 10.1016/j.athoracsur.2019.11.042.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementNonindex readmissionsCardiac surgeryNonindex hospitalNonindex hospital readmissionsCoronary artery bypassNational Readmission DatabaseAortic valve replacementCardiac surgery patientsMajor cardiac surgeryPatient risk profileHigh-volume centersUS adult patientsRegionalization of careFragmentation of careComorbidity burdenHospital mortalityIndex readmissionArtery bypassInitial hospitalizationAdult patientsSurgery patientsValve replacementHospital readmissionIndependent predictors
2019
Does This Patient Have Hip Osteoarthritis?
Metcalfe D, Perry DC, Claireaux HA, Simel DL, Zogg CK, Costa ML. Does This Patient Have Hip Osteoarthritis? JAMA 2019, 322: 2323-2333. PMID: 31846019, PMCID: PMC7583647, DOI: 10.1001/jama.2019.19413.Peer-Reviewed Original ResearchConceptsHip osteoarthritisGroin painRadiographic evidenceClinical findingsHip adductionSevere hip osteoarthritisAbsence of osteoarthritisPrimary care physiciansRisk of biasLevel of evidenceDiagnostic Accuracy Studies toolLikelihood ratioCombination of findingsIndividual hipPosterior painAffected hipAbductor weaknessKnee osteoarthritisCare physiciansPlain radiographyPlain radiographsContralateral legCommon causeFamily historyPassive abductionDebunking the July Effect in Cardiac Surgery: A National Analysis of More Than 470,000 Procedures
Shah RM, Hirji SA, Kiehm S, Goel S, Yazdchi F, Bellavia A, Zogg CK, Pelletier MP, Shekar P, Kaneko T. Debunking the July Effect in Cardiac Surgery: A National Analysis of More Than 470,000 Procedures. The Annals Of Thoracic Surgery 2019, 108: 929-934. PMID: 31353035, DOI: 10.1016/j.athoracsur.2019.06.015.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAdultAgedCardiac Surgical ProceduresClinical CompetenceCohort StudiesDatabases, FactualEducation, Medical, GraduateFemaleHospital MortalityHospitals, TeachingHumansInpatientsInternship and ResidencyMaleMedical Staff, HospitalMiddle AgedPostoperative ComplicationsQuality of Health CareRisk AdjustmentSeasonsUnited StatesConceptsAortic valve replacementCardiac surgeryJuly effectHospital mortalityPatient outcomesTeaching hospitalMajor cardiac surgery proceduresSurgical aortic valve replacementCoronary artery bypassCardiac surgery proceduresNational Inpatient SampleRisk-adjusted mortalityMitral valve repairCardiac surgery outcomesHospital complicationsArtery bypassMV surgeryNoncardiac surgeryValve replacementAdjusted mortalityValve repairSurgery outcomesInpatient SampleWorse outcomesHospital support systemsTotal hip arthroplasty versus hemiarthroplasty for independently mobile older adults with intracapsular hip fractures
Metcalfe D, Judge A, Perry DC, Gabbe B, Zogg CK, Costa ML. Total hip arthroplasty versus hemiarthroplasty for independently mobile older adults with intracapsular hip fractures. BMC Musculoskeletal Disorders 2019, 20: 226. PMID: 31101041, PMCID: PMC6525472, DOI: 10.1186/s12891-019-2590-4.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overArthroplasty, Replacement, HipFemur HeadFracture DislocationHemiarthroplastyHip FracturesHumansIndependent LivingMiddle AgedPatient SelectionPostoperative ComplicationsQuality of LifeRandomized Controlled Trials as TopicRegistriesReoperationRisk FactorsUnited KingdomConceptsTotal hip arthroplastyNational Hip Fracture DatabaseHospital Episode StatisticsHip fractureIntracapsular hip fracturesMobile older adultsTHA dislocationOlder adultsHip arthroplastyPropensity scoreHealth-related qualityHip Fracture DatabaseClinical registry dataLength of stayMethodsA systematic reviewUrgent further studyDeath registration dataResultsFive RCTsFit patientsSecondary outcomesPrimary outcomeEpisode StatisticsSafety profileSurgical interventionFunctional outcomeAssociation of Medicaid Expansion With Access to Rehabilitative Care in Adult Trauma Patients
Zogg CK, Scott JW, Metcalfe D, Gluck AR, Curfman GD, Davis KA, Dimick JB, Haider AH. Association of Medicaid Expansion With Access to Rehabilitative Care in Adult Trauma Patients. JAMA Surgery 2019, 154: 402-411. PMID: 30601888, PMCID: PMC6537775, DOI: 10.1001/jamasurg.2018.5177.Peer-Reviewed Original ResearchConceptsAdult trauma patientsTrauma patientsMedicaid expansionNonexpansion statesInsurance coverageAffordable Care ActExpansion statesPatient ProtectionInpatient rehabilitation facilityCare ActSkilled nursing facilitiesMedicaid expansion statesSex-based disparitiesHome health agenciesRace/ethnicityPostdischarge careTrauma populationFunctional outcomeRehabilitation gainsLeading causeRehabilitative careTrauma outcomesMAIN OUTCOMENursing facilitiesRehabilitation facilityChanges in Discharge to Rehabilitation: Potential Unintended Consequences of Medicare Total Hip Arthroplasty/Total Knee Arthroplasty Bundled Payments, Should They Be Implemented on a Nationwide Scale?
Zogg CK, Falvey JR, Dimick JB, Haider AH, Davis KA, Grauer JN. Changes in Discharge to Rehabilitation: Potential Unintended Consequences of Medicare Total Hip Arthroplasty/Total Knee Arthroplasty Bundled Payments, Should They Be Implemented on a Nationwide Scale? The Journal Of Arthroplasty 2019, 34: 1058-1065.e4. PMID: 30878508, PMCID: PMC6884960, DOI: 10.1016/j.arth.2019.01.068.Peer-Reviewed Original ResearchMeSH KeywordsAgedArthroplasty, Replacement, HipArthroplasty, Replacement, KneeComputer SimulationDecision TreesElective Surgical ProceduresHumansMedicareMiddle AgedMonte Carlo MethodPatient DischargePatient Protection and Affordable Care ActPatient ReadmissionQuality of LifeRehabilitationReimbursement MechanismsSkilled Nursing FacilitiesUnited StatesConceptsExtent of therapyHealth-related qualityType of rehabilitationFunctional recoveryPatients' health-related qualitySkilled nursing facility useElective total hipPrimary TKA patientsOutcomes of patientsPatient-centered outcomesPatients' functional recoveryInpatient rehabilitation facilityNursing facility useEpisode of careAverage functional outcomeBundled payment programsDischarge dispositionTKA patientsUnplanned readmissionTotal hipFunctional outcomeAffordable Care ActOutcome measuresRehabilitation facilityBundled PaymentsImpact of Affordable Care Act–related insurance expansion policies on mortality and access to post-discharge care for trauma patients
Scott JW, Neiman PU, Uribe-Leitz T, Scott KW, Zogg CK, Salim A, Haider AH. Impact of Affordable Care Act–related insurance expansion policies on mortality and access to post-discharge care for trauma patients. Journal Of Trauma And Acute Care Surgery 2019, 86: 196-205. PMID: 30694984, DOI: 10.1097/ta.0000000000002117.Peer-Reviewed Original ResearchConceptsPost-discharge careTrauma patientsInpatient mortalityPost-acute careAffordable Care ActCoverage expansion policiesUninsured ratePost-acute care facilitiesState-level Medicaid expansionMedicaid expansionNational Trauma Data BankPolicy-associated changesAdult trauma patientsTrauma Data BankPost-acute servicesUninsured trauma patientsCare ActHome health servicesInsurance coverage expansionCoverage expansionPost-policy periodPatients 18Discharge dispositionPatient demographicsInjury characteristicsAssociation of Medicaid Expansion Policy with Outcomes in Homeless Patients Requiring Emergency General Surgery
Manzano‐Nunez R, Zogg CK, Bhulani N, McCarty JC, Herrera‐Escobar J, Lu K, Andriotti T, Uribe‐Leitz T, de Jager E, Jarman MP, Haider AH, Ortega G. Association of Medicaid Expansion Policy with Outcomes in Homeless Patients Requiring Emergency General Surgery. World Journal Of Surgery 2019, 43: 1483-1489. PMID: 30706104, DOI: 10.1007/s00268-019-04932-0.Peer-Reviewed Original ResearchConceptsEmergency general surgeryNon-expansion statesMedical adviceHomeless patientsSurgical complicationsMedicaid expansionHospital chargesGeneral surgeryLower oddsPrimary EGS diagnosesHome healthcareMultivariable logistic regressionExpansion statesLength of stayNon-Medicaid expansion statesState Inpatient DatabasesMedicaid expansion statesMultivariable quantile regressionEGS proceduresClinical eventsEGS diagnosesInpatient DatabaseHomeless individualsHigher oddsNon-significant difference
2018
Patient Presentations in Outpatient Settings
Zogg CK, Haring RS, Xu L, Canner JK, Ottesen TD, Salim A, Haider AH, Schneider EB. Patient Presentations in Outpatient Settings. Epidemiology 2018, 29: 885-894. PMID: 30063541, PMCID: PMC6167152, DOI: 10.1097/ede.0000000000000900.Peer-Reviewed Original ResearchConceptsInjury-specific factorsOutpatient settingHead traumaTrauma patientsEmergency departmentIndex outpatient visitAmbulatory care useHead trauma patientsEmergency department careOutpatient presentationClinic visitsIndex presentationOutpatient visitsOutpatient burdenCare useOutpatient casesIncidence ratePatient presentationCommercial ClaimsTrauma diagnosisSubsequent visitsAnnual burdenTrauma trendsDisease controlPatientsImpact of Affordable Care Act Insurance Expansion on Pre-Hospital Access to Care: Changes in Adult Perforated Appendix Admission Rates after Medicaid Expansion and the Dependent Coverage Provision
Zogg CK, Scott JW, Bhulani N, Gluck AR, Curfman GD, Davis KA, Dimick JB, Haider AH. Impact of Affordable Care Act Insurance Expansion on Pre-Hospital Access to Care: Changes in Adult Perforated Appendix Admission Rates after Medicaid Expansion and the Dependent Coverage Provision. Journal Of The American College Of Surgeons 2018, 228: 29-43.e1. PMID: 30359835, DOI: 10.1016/j.jamcollsurg.2018.09.022.Peer-Reviewed Original ResearchConceptsMedicaid expansionAffordable Care ActAdmission ratesPerforation rateInsurance coverageAffordable Care Act's insurance expansionInsurance expansionYoung adultsAcute surgical careDependent coverage provisionBetter patient outcomesFederal poverty levelRace/ethnicityAcute appendicitisHospitalized adultsAcute careParents' insuranceInpatient claimsPatient outcomesACA's impactSurgical careRisk populationsNonexpansion statesPrivileged patientsAge 26Insurance Status Biases Trauma-system Utilization and Appropriate Interfacility Transfer
Zogg CK, Schuster KM, Maung AA, Davis KA. Insurance Status Biases Trauma-system Utilization and Appropriate Interfacility Transfer. Annals Of Surgery 2018, 268: 681-689. PMID: 30004929, DOI: 10.1097/sla.0000000000002954.Peer-Reviewed Original ResearchConceptsNTC patientsMajor injuriesOlder adult trauma patientsNationwide Emergency Department SampleOptimal trauma careAdult trauma patientsEmergency department admissionsEmergency Department SampleTrauma center careTransfer of patientsComplex traumatic injuriesMultilevel logistic regressionTrauma patientsDepartment admissionsHigh morbidityTC careDirect admissionInsurance statusInterfacility transferUninsured patientsTrauma careTraumatic injuryOutcome measuresTrauma systemCenter careChanging prognosis of oral cancer: An analysis of survival and treatment between 1973 and 2014
Cheraghlou S, Schettino A, Zogg CK, Judson BL. Changing prognosis of oral cancer: An analysis of survival and treatment between 1973 and 2014. The Laryngoscope 2018, 128: 2762-2769. PMID: 30194691, DOI: 10.1002/lary.27315.Peer-Reviewed Original ResearchConceptsOral cavity cancerLate-stage diseaseAdjuvant therapyOral cancerEnd Results 9 registriesCox survival regressionHigher nodal yieldsNational Cancer DatabaseEarly-stage diseaseKaplan-Meier analysisRetrospective database analysisAnalysis of survivalAdjuvant chemoradiotherapyNodal yieldAdult patientsNeck dissectionRetrospective studyCancer DatabasePrognosisPatientsCancerDiseaseDatabase analysisSurvival regressionChemoradiotherapyManagement of metastatic melanoma: improved survival in a national cohort following the approvals of checkpoint blockade immunotherapies and targeted therapies
Dobry AS, Zogg CK, Hodi FS, Smith TR, Ott PA, Iorgulescu JB. Management of metastatic melanoma: improved survival in a national cohort following the approvals of checkpoint blockade immunotherapies and targeted therapies. Cancer Immunology, Immunotherapy 2018, 67: 1833-1844. PMID: 30191256, PMCID: PMC6249064, DOI: 10.1007/s00262-018-2241-x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAntineoplastic Agents, ImmunologicalComorbidityDisease ManagementFemaleHealth Care SurveysHumansImmunotherapyMaleMelanomaMiddle AgedMolecular Targeted TherapyNeoplasm StagingOdds RatioProtein Kinase InhibitorsProto-Oncogene Proteins B-rafRegistriesSymptom AssessmentUnited StatesYoung AdultConceptsStage 4 melanomaOverall survivalInitial approvalCutaneous melanomaLandmark survival analysisSubstantial clinical efficacyImproved overall survivalMetastatic cutaneous melanomaNational Cancer DatabaseStage 4 diseaseCheckpoint blockade immunotherapySurvival of patientsRisk-adjusted analysisBlockade immunotherapyCheckpoint blockadeNovel immunotherapiesMultivariable analysisClinical efficacyMetastatic melanomaNational cohortCancer DatabaseUninsured patientsClinical trialsPatientsSurvival analysisImproved Risk-Adjusted Survival for Melanoma Brain Metastases in the Era of Checkpoint Blockade Immunotherapies: Results from a National Cohort
Iorgulescu JB, Harary M, Zogg CK, Ligon KL, Reardon DA, Hodi FS, Aizer AA, Smith TR. Improved Risk-Adjusted Survival for Melanoma Brain Metastases in the Era of Checkpoint Blockade Immunotherapies: Results from a National Cohort. Cancer Immunology Research 2018, 6: 1039-1045. PMID: 30002157, PMCID: PMC6230261, DOI: 10.1158/2326-6066.cir-18-0067.Peer-Reviewed Original ResearchConceptsMelanoma brain metastasesCheckpoint blockade immunotherapyMBM patientsOverall survivalBlockade immunotherapyStage 4 melanomaNational Cancer DatabaseManagement of patientsKaplan-Meier techniqueLarge national cohortEarly clinical trialsBrain metastasesExtracranial metastasesSurvival benefitAdvanced melanomaOS improvementNational cohortCancer DatabaseClinical trialsNovel therapiesU.S. cancerPatientsTherapy trialsProportional hazardsFDA approvalAdjuvant Chemotherapy Is Associated With Improved Survival for Late‐Stage Salivary Squamous Cell Carcinoma
Cheraghlou S, Schettino A, Zogg CK, Otremba MD, Bhatia A, Park HS, Osborn HA, Mehra S, Yarbrough WG, Judson BL. Adjuvant Chemotherapy Is Associated With Improved Survival for Late‐Stage Salivary Squamous Cell Carcinoma. The Laryngoscope 2018, 129: 883-889. PMID: 30151947, DOI: 10.1002/lary.27444.Peer-Reviewed Original ResearchMeSH KeywordsAgedCarcinoma, Squamous CellChemoradiotherapy, AdjuvantChemotherapy, AdjuvantCombined Modality TherapyFemaleHumansKaplan-Meier EstimateMaleMiddle AgedNeoplasm StagingPropensity ScoreProportional Hazards ModelsRadiotherapy, AdjuvantRetrospective StudiesSalivary Gland NeoplasmsSurvival RateTreatment OutcomeConceptsLate-stage patientsSquamous cell carcinomaAdjuvant radiotherapyAdjuvant therapyAdjuvant chemoradiotherapyAdjuvant chemotherapyImproved survivalCell carcinomaImproved long-term survivalCox survival regressionPrimary cutaneous malignanciesUnique disease entityAddition of chemotherapyNational Cancer DatabaseEarly-stage diseaseFive-year survivalEarly-stage patientsKaplan-Meier analysisParotid gland cancerLate stage groupLong-term survivalSurvival benefitCutaneous malignanciesPoor prognosisRetrospective study