2024
T166 Treatment Outcomes From Computerized CBT for Substance Use Disorders Among People With Criminal Justice Involvement
Loya J, Babuscio T, Nich C, Kiluk B. T166 Treatment Outcomes From Computerized CBT for Substance Use Disorders Among People With Criminal Justice Involvement. Drug And Alcohol Dependence 2024, 260: 110615. DOI: 10.1016/j.drugalcdep.2023.110615.Peer-Reviewed Original ResearchUnderstanding the patient and supporter journey in cocaine use disorder
Leclair D, Waye K, Gomez-Mancilla B, Kiluk B, Karanam A, Banerjee P, Muthusamy V, Maahs S. Understanding the patient and supporter journey in cocaine use disorder. Frontiers In Psychiatry 2024, 15: 1230626. PMID: 38659460, PMCID: PMC11040082, DOI: 10.3389/fpsyt.2024.1230626.Peer-Reviewed Original ResearchPatient perspectives on current and potential therapies and clinical trial approaches for cocaine use disorder
Maahs S, Leclair D, Gomez-Mancilla B, Kiluk B, Muthusamy V, Banerjee P, Dasgupta S, Waye K. Patient perspectives on current and potential therapies and clinical trial approaches for cocaine use disorder. Frontiers In Psychiatry 2024, 15: 1230699. PMID: 38487570, PMCID: PMC10937549, DOI: 10.3389/fpsyt.2024.1230699.Peer-Reviewed Original ResearchCocaine use disorderLong-term abstinenceSubstance use disordersBarriers to therapyWithdrawal symptomsUse disorderCraving controlClinical trialsCocaineClinical trial approachesDesign of clinical trialsCravingScreening questionnaireDisordersClinical trial outcomesTrial outcomesPerspectives of individualsRemissionParticipantsDrug seekersPotential therapiesTherapyIndividualsRecruited participantsAbstinence
2023
The Effect of Cognitive Behavioral Therapy on Impulsivity in Addictive Disorders: a Narrative Review
Loya J, Benitez B, Kiluk B. The Effect of Cognitive Behavioral Therapy on Impulsivity in Addictive Disorders: a Narrative Review. Current Addiction Reports 2023, 10: 485-493. PMID: 38269068, PMCID: PMC10805411, DOI: 10.1007/s40429-023-00491-6.Peer-Reviewed Original ResearchCognitive behavioral therapyBehavioral therapySubstance useAddictive disordersFuture clinical trialsPoor treatment outcomesEvidence-based treatmentsMeasures of impulsivityCycle of addictionCBT effectsRisk factorsClinical trialsTreatment outcomesRecent FindingsThereNarrative reviewCharacteristics of addictionLimited evidenceRange of addictionsAssessment of impulsivityTherapyAddictionTrialsDisordersImpulsivityAddictive behaviors
2020
Evaluating a Longitudinal Mediation Model of Perceived Stress, Depressive Symptoms, and Substance Use Treatment Outcomes
Roos CR, Kiluk BD, McHugh RK, Carroll KM. Evaluating a Longitudinal Mediation Model of Perceived Stress, Depressive Symptoms, and Substance Use Treatment Outcomes. Psychology Of Addictive Behaviors 2020, 34: 660-668. PMID: 32297754, PMCID: PMC7483283, DOI: 10.1037/adb0000581.Peer-Reviewed Original ResearchConceptsIllicit opioid useOpioid useDepressive symptomsUse disordersSubstance use outcomesMethadone treatmentStandard methadone treatmentTrial of galantamineUse outcomesOpioid use disorderSubstance Use Treatment OutcomesSubstance use disordersCocaine use disorderCognitive behavioral therapyLongitudinal treatment studyTreatment outcomesPredictors of endPosttreatment outcomesSymptomsTreatment studiesSignificant total effectSubstance useBaselineOutcomesDisordersThe search for mechanisms of cognitive behavioral therapy for alcohol or other drug use disorders: A systematic review
Magill M, Tonigan JS, Kiluk B, Ray L, Walthers J, Carroll K. The search for mechanisms of cognitive behavioral therapy for alcohol or other drug use disorders: A systematic review. Behaviour Research And Therapy 2020, 131: 103648. PMID: 32474226, PMCID: PMC7329023, DOI: 10.1016/j.brat.2020.103648.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyDrug use disordersUse disordersSystematic reviewBehavioral therapyRandomized clinical trialsStudy inclusion criteriaPatient behavior changeCBT-based treatmentClinical trialsInclusion criteriaStatistical mediatorMediator candidatesIntervention ingredientsProject MATCHCBT mechanismsTherapyBehavior change frameworkMediatorsBehavior changeDisordersAddiction researchReportReviewReview sampleShort- and long-term changes in substance-related coping as mediators of in-person and computerized CBT for alcohol and drug use disorders
Roos CR, Carroll KM, Nich C, Frankforter T, Kiluk BD. Short- and long-term changes in substance-related coping as mediators of in-person and computerized CBT for alcohol and drug use disorders. Drug And Alcohol Dependence 2020, 212: 108044. PMID: 32422538, PMCID: PMC7293942, DOI: 10.1016/j.drugalcdep.2020.108044.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyComputerized cognitive behavioral therapyPerson cognitive-behavioural therapySubstance use disordersMediation effectAlcohol use disorderComputer-delivered cognitive behavioural therapyUse disordersSame mediation effectSubstance-related copingCoping Strategies ScaleSignificant mediation effectMechanisms of changeMediational modelCoping skillsStrategies ScaleCBT4CBTStatistical mediatorCopingDrug use disordersSubstance useHeavy drinkingDisordersLong-term changesLong-term increase
2019
Anhedonia as a Key Clinical Feature in the Maintenance and Treatment of Opioid Use Disorder
Kiluk BD, Yip SW, DeVito EE, Carroll KM, Sofuoglu M. Anhedonia as a Key Clinical Feature in the Maintenance and Treatment of Opioid Use Disorder. Clinical Psychological Science 2019, 7: 1190-1206. PMID: 32042509, PMCID: PMC7009780, DOI: 10.1177/2167702619855659.Peer-Reviewed Original ResearchOpioid use disorderClinical featuresUse disordersHigher anhedonia scoresKey clinical featuresRate of participantsAnhedonia scoresOpioid-dependent sampleOpioid cravingOpioid useTreatment adherenceHealthy controlsSignificant anhedoniaPharmacological interventionsAssessment of anhedoniaMajority of studiesPotential targetAnhedoniaTreatmentTime courseDisordersSignificant knowledge gapsScoresPotential implicationsCritical need
2018
Accounting for the uncounted: Physical and affective distress in individuals dropping out of oral naltrexone treatment for opioid use disorder
Carroll KM, Nich C, Frankforter TL, Yip SW, Kiluk BD, DeVito EE, Sofuoglu M. Accounting for the uncounted: Physical and affective distress in individuals dropping out of oral naltrexone treatment for opioid use disorder. Drug And Alcohol Dependence 2018, 192: 264-270. PMID: 30300800, PMCID: PMC6203294, DOI: 10.1016/j.drugalcdep.2018.08.019.Peer-Reviewed Original ResearchConceptsOpioid use disorderOral naltrexoneUse disordersAffective symptomsVoucher-based contingency managementDysphoric symptomsAffective distressOral naltrexone treatmentMultiple baseline characteristicsBaseline characteristicsNaltrexone treatmentHigh riskNaltrexoneSomatic symptomsSymptomsContingency managementTreatmentHigh rateDistressSubstantial evidenceTrialsTheoretical benefitsDisordersAffective discomfortParticipantsCulturally Adapted, Web-Based Cognitive Behavioral Therapy for Spanish-Speaking Individuals With Substance Use Disorders: A Randomized Clinical Trial.
Paris M, Silva M, Añez-Nava L, Jaramillo Y, Kiluk BD, Gordon MA, Nich C, Frankforter T, Devore K, Ball SA, Carroll KM. Culturally Adapted, Web-Based Cognitive Behavioral Therapy for Spanish-Speaking Individuals With Substance Use Disorders: A Randomized Clinical Trial. American Journal Of Public Health 2018, 108: 1535-1542. PMID: 30252519, PMCID: PMC6187780, DOI: 10.2105/ajph.2018.304571.Peer-Reviewed Original ResearchConceptsSubstance use disordersCognitive-behavioral treatmentUse disordersSubstance use outcomesClinical trialsWeb-based cognitive behavioral therapyCurrent substance use disorderUse outcomesRandomized clinical trialsStandard outpatient treatmentEvidence-based treatmentsCognitive behavioral therapyPrimary outcomeStandard treatmentOutpatient treatmentStandard outpatientTreatment completionHealth disparitiesBehavioral therapyBehavioral treatmentAddiction treatmentTreatment-seeking individualsGreater reductionTreatmentDisordersWhat defines a clinically meaningful outcome in the treatment of substance use disorders: reductions in direct consequences of drug use or improvement in overall functioning?
Kiluk BD, Fitzmaurice GM, Strain EC, Weiss RD. What defines a clinically meaningful outcome in the treatment of substance use disorders: reductions in direct consequences of drug use or improvement in overall functioning? Addiction 2018, 114: 9-15. PMID: 29900624, PMCID: PMC6289694, DOI: 10.1111/add.14289.Peer-Reviewed Original ResearchConceptsSubstance use disordersDrug useUse disordersMost substance use disordersTreatment Efficacy TrialMeaningful outcomesOverall functioningException of alcoholAlcohol-related consequencesAspects of functioningPharmacotherapy trialsEfficacy trialsHealth consequencesIndividual functioningTrialsLong-term functioningWeak associationDisordersCurrent standardFunctioningUse trialOutcomesAssociationAbstinence
2015
Measures of outcome for stimulant trials: ACTTION recommendations and research agenda
Kiluk BD, Carroll KM, Duhig A, Falk DE, Kampman K, Lai S, Litten RZ, McCann DJ, Montoya ID, Preston KL, Skolnick P, Weisner C, Woody G, Chandler R, Detke MJ, Dunn K, Dworkin RH, Fertig J, Gewandter J, Moeller FG, Ramey T, Ryan M, Silverman K, Strain EC. Measures of outcome for stimulant trials: ACTTION recommendations and research agenda. Drug And Alcohol Dependence 2015, 158: 1-7. PMID: 26652899, PMCID: PMC4698050, DOI: 10.1016/j.drugalcdep.2015.11.004.Peer-Reviewed Original ResearchConceptsStimulant use disorderClinical trialsMeaningful outcome measuresUse disordersTreatment successOutcome measuresStimulant abstinenceAddiction Clinical Trial TranslationsFuture clinical trialsClinical trial endpointsClinical trial dataAlcohol use disorderMeasures of outcomeValidation of PatientStimulant trialsTrial endpointsEfficacious pharmacotherapiesUrine testingSustained abstinenceTrial dataSecondary analysisStimulant useTrialsPsychosocial benefitsDisordersThe acquisition of coping skills from computerized cognitive behavioral therapy for substance use disorders: It's all where you start
Kiluk B, DeVito E, Buck M, Nich C, Carroll K. The acquisition of coping skills from computerized cognitive behavioral therapy for substance use disorders: It's all where you start. Drug And Alcohol Dependence 2015, 156: e110. DOI: 10.1016/j.drugalcdep.2015.07.305.Commentaries, Editorials and LettersActive Ingredients of Treatment and Client Mechanisms of Change in Behavioral Treatments for Alcohol Use Disorders: Progress 10 Years Later
Magill M, Kiluk BD, McCrady BS, Tonigan JS, Longabaugh R. Active Ingredients of Treatment and Client Mechanisms of Change in Behavioral Treatments for Alcohol Use Disorders: Progress 10 Years Later. Alcohol Clinical And Experimental Research 2015, 39: 1852-1862. PMID: 26344200, PMCID: PMC4592447, DOI: 10.1111/acer.12848.Peer-Reviewed Original ResearchConceptsAlcohol use disorderBehavioral treatmentUse disordersCognitive behavioral therapyActive treatment ingredientsEvidence-based treatmentsTreatment ingredientsBehavioral therapyMotivational interviewingIntervention workFourth treatment modalityBehavioral interventionsDrug use disordersAlcohol behaviorCurrent theoriesCurrent reviewBehavior changeRobust research agendaEvaluation of progressDisordersResearch agendaTreatment modalitiesConceptual frameworkResearchActive ingredients
2013
Technology-based interventions for the treatment and recovery management of substance use disorders: A JSAT special issue
Marsch LA, Carroll KM, Kiluk BD. Technology-based interventions for the treatment and recovery management of substance use disorders: A JSAT special issue. Journal Of Substance Use And Addiction Treatment 2013, 46: 1-4. PMID: 24041749, PMCID: PMC3825739, DOI: 10.1016/j.jsat.2013.08.010.Peer-Reviewed Original Research
2011
A Methodological Analysis of Randomized Clinical Trials of Computer-Assisted Therapies for Psychiatric Disorders: Toward Improved Standards for an Emerging Field
Kiluk BD, Sugarman DE, Nich C, Gibbons CJ, Martino S, Rounsaville BJ, Carroll KM. A Methodological Analysis of Randomized Clinical Trials of Computer-Assisted Therapies for Psychiatric Disorders: Toward Improved Standards for an Emerging Field. American Journal Of Psychiatry 2011, 168: 790-799. PMID: 21536689, PMCID: PMC3607199, DOI: 10.1176/appi.ajp.2011.10101443.Peer-Reviewed Original ResearchConceptsComputer-assisted therapyRandomized clinical trialsPsychiatric disordersClinical trialsMethodological qualityEvidence-based behavioral therapiesMethodological Quality IndexPotential adverse eventsEvidence-based therapiesAxis I DisordersAdult psychiatric disordersMethodological quality scoreEvidence-based interventionsAdverse eventsTreat principleRandomized trialsI disordersStudy qualityTreatment exposureTherapyBehavioral therapyCost-effective strategyDisordersTrialsCurrent standard
2008
Sport Participation and Anxiety in Children with ADHD
Kiluk BD, Weden S, Culotta VP. Sport Participation and Anxiety in Children with ADHD. Journal Of Attention Disorders 2008, 12: 499-506. PMID: 18596300, DOI: 10.1177/1087054708320400.Peer-Reviewed Original ResearchConceptsLearning disorderDepression symptomsParent-report measuresAnxiety problemsSports participationEmotional functioningPsychological benefitsADHDAnxietyActive sport participationComparison groupMoodChildrenPhysical activityMore sportsFunctioningSportsSymptomsParticipationDisordersMeasuresScoresRelationshipBehavior
2007
Contingency Management to Reduce Substance Use in Individuals Who are Homeless with Co-Occurring Psychiatric Disorders
Tracy K, Babuscio T, Nich C, Kiluk B, Carroll KM, Petry NM, Rounsaville BJ. Contingency Management to Reduce Substance Use in Individuals Who are Homeless with Co-Occurring Psychiatric Disorders. The American Journal Of Drug And Alcohol Abuse 2007, 33: 253-258. PMID: 17497548, PMCID: PMC3390023, DOI: 10.1080/00952990601174931.Peer-Reviewed Original Research