2024
Measurement invariance of the Perceived Stress Scale across race, sex, and time, and differential impacts on cocaine use treatment outcomes
Schick M, Kiluk B, Nich C, LaPaglia D, Haeny A. Measurement invariance of the Perceived Stress Scale across race, sex, and time, and differential impacts on cocaine use treatment outcomes. Journal Of Substance Use And Addiction Treatment 2024, 166: 209493. PMID: 39151798, PMCID: PMC11392621, DOI: 10.1016/j.josat.2024.209493.Peer-Reviewed Original ResearchCocaine use disorderPerceived Stress ScaleTreatment retentionMeasurement invarianceTreatment outcomesSubstance use treatment outcomesStress ScalePredicting treatment retentionSelf-efficacyCoping self-efficacyTwo-factor modelInfluence treatment outcomeCocaine abuse/dependenceDSM-IVUse disorderCocaine useBetween-group differencesMetric invarianceScalar invarianceTwo-factorCocainePharmacological treatmentFactor analysisDifferential impactAbuse/dependenceStructural brain changes associated with cocaine use and digital cognitive behavioral therapy in cocaine use disorder treatment
McCurdy L, DeVito E, Loya J, Nich C, Zhai Z, Kiluk B, Potenza M. Structural brain changes associated with cocaine use and digital cognitive behavioral therapy in cocaine use disorder treatment. Drug And Alcohol Dependence Reports 2024, 11: 100246. PMID: 38966567, PMCID: PMC11222934, DOI: 10.1016/j.dadr.2024.100246.Peer-Reviewed Original ResearchCocaine use disorderCognitive behavioral therapyCocaine useBehavioral therapyBrain changesBrain structuresWhole-brain voxel-based morphometry analysisCocaine use disorder treatmentLevel of cocaine useWeeks of outpatient treatmentVoxel-based morphometry analysisDigital cognitive behavioral therapyT1-weighted magnetic resonance imaging scansRight caudate bodyAssociated with cocaine useMethadone-maintained individualsGray matter volumeStructural brain changesFunction of engagementCaudate bodyRight caudateCUD treatmentMatter volumeUse disorderBilateral cerebellumExamining cocaine use reductions and long-term outcomes in two clinical trials of continuing care for cocaine dependence
Votaw V, Tuchman F, Roos C, Hebden H, McKay J, Kiluk B, Witkiewitz K. Examining cocaine use reductions and long-term outcomes in two clinical trials of continuing care for cocaine dependence. Journal Of Substance Use And Addiction Treatment 2024, 163: 209394. PMID: 38735481, PMCID: PMC11180556, DOI: 10.1016/j.josat.2024.209394.Peer-Reviewed Original ResearchCocaine use disorderCocaine useAssociated with less cocaine useTelephone-based continuing careLevel of cocaine useFollow-upDrug use consequencesAssociated with lower levelsClinical trialsBaseline to 12-month follow-upCocaine dependenceTreatment entryProblem severityUse disorderTimeline FollowbackCocaineInitial treatment phaseAbstinenceLow-frequency useLong-term functional outcomeEffect sizeTreatment phaseLong-term outcomesRandomized clinical trialsNegative consequences
2023
Percentage of negative urine drug screens as a clinically meaningful endpoint for RCTs evaluating treatment for cocaine use
Loya J, Babuscio T, Nich C, Alessi S, Rash C, Kiluk B. Percentage of negative urine drug screens as a clinically meaningful endpoint for RCTs evaluating treatment for cocaine use. Drug And Alcohol Dependence 2023, 248: 109947. PMID: 37276806, PMCID: PMC10498479, DOI: 10.1016/j.drugalcdep.2023.109947.Peer-Reviewed Original ResearchConceptsUrine drug screensClinical trialsMeaningful endpointsCocaine useLong-term clinical benefitBetter long-term outcomesDrug screensPsychosocial functioningNegative urine drug screensLong-term outcomesRandomized clinical trialsFuture clinical trialsBetter psychosocial functioningClinical benefitPharmacological treatmentContinuous abstinenceTreatment periodTreatment respondersSustained abstinenceSubstance useTrialsTreatmentMeaningful thresholdPooled datasetAbstinence
2019
Sociodemographic and clinical outcome differences among individuals seeking treatment for cocaine use disorders. The intersection of gender and race
Miguel AQC, Jordan A, Kiluk BD, Nich C, Babuscio TA, Mari JJ, Carroll KM. Sociodemographic and clinical outcome differences among individuals seeking treatment for cocaine use disorders. The intersection of gender and race. Journal Of Substance Use And Addiction Treatment 2019, 106: 65-72. PMID: 31540613, PMCID: PMC6756185, DOI: 10.1016/j.jsat.2019.08.014.Peer-Reviewed Original ResearchConceptsCocaine use disorderTreatment trialsTreatment outcomesUse disordersWhite womenTreatment outcome indicatorsPoor overall outcomeClinical outcome differencesRandomized clinical trialsFocused treatment approachMore effective treatmentsDifferent psychosocial issuesSubstance use problemsSubgroup of individualsBaseline characteristicsPoor outcomePsychiatric comorbidityClinical trialsHigh prevalenceSociodemographic statusEffective treatmentOutcome differencesTreatment approachesPsychosocial issuesCocaine use
2016
Just Showing Up Is Not Enough: Homework Adherence and Outcome in Cognitive–Behavioral Therapy for Cocaine Dependence
Decker SE, Kiluk BD, Frankforter T, Babuscio T, Nich C, Carroll KM. Just Showing Up Is Not Enough: Homework Adherence and Outcome in Cognitive–Behavioral Therapy for Cocaine Dependence. Journal Of Consulting And Clinical Psychology 2016, 84: 907-912. PMID: 27454780, PMCID: PMC5341374, DOI: 10.1037/ccp0000126.Peer-Reviewed Original ResearchConceptsUrine toxicology screenCognitive behavioral therapyCocaine use outcomesHomework adherenceTreatment attendanceToxicology screenCocaine useUse outcomesMultiple logistic regressionBaseline cocaine useVariety of disordersCocaine use severityTreatment endClinical trialsCocaine use frequencyImproved outcomesCocaine dependenceLogistic regressionCBT sessionsAdherenceUse severityPrior studiesGreater reductionOutcomesTreatment
2014
Toward empirical identification of a clinically meaningful indicator of treatment outcome: Features of candidate indicators and evaluation of sensitivity to treatment effects and relationship to one year follow up cocaine use outcomes
Carroll KM, Kiluk BD, Nich C, DeVito EE, Decker S, LaPaglia D, Duffey D, Babuscio TA, Ball SA. Toward empirical identification of a clinically meaningful indicator of treatment outcome: Features of candidate indicators and evaluation of sensitivity to treatment effects and relationship to one year follow up cocaine use outcomes. Drug And Alcohol Dependence 2014, 137: 3-19. PMID: 24556275, PMCID: PMC4042667, DOI: 10.1016/j.drugalcdep.2014.01.012.Peer-Reviewed Original Research
2013
Smokers Versus Snorters: Do Treatment Outcomes Differ According to Route of Cocaine Administration?
Kiluk BD, Babuscio TA, Nich C, Carroll KM. Smokers Versus Snorters: Do Treatment Outcomes Differ According to Route of Cocaine Administration? Experimental And Clinical Psychopharmacology 2013, 21: 490-498. PMID: 24364538, PMCID: PMC3943602, DOI: 10.1037/a0034173.Peer-Reviewed Original ResearchConceptsTreatment outcomesCocaine administrationAddiction Severity Index composite scoresIntranasal usersComposite scoreRoute of administrationCocaine use outcomesPrimary routeIntranasal routeClinical trialsSustained abstinenceCocaine-dependent individualsTreatment phaseSmokersCocaine useStudy periodAdministrationUse outcomesSeverity of problemsMaximal concentrationStatistical significanceASI domainsOutcomesDifferential changesCocaine