1996
Ca2+ stimulates both the respiratory and phosphorylation subsystems in rat heart mitochondria
MILDAZIENE V, BANIENE R, NAUCIENE Z, MARCINKEVICIUTE A, MORKUNIENE R, BORUTAITE V, KHOLODENKO B, BROWN G. Ca2+ stimulates both the respiratory and phosphorylation subsystems in rat heart mitochondria. Biochemical Journal 1996, 320: 329-334. PMID: 8947505, PMCID: PMC1217935, DOI: 10.1042/bj3200329.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCalciumKineticsMaleMembrane PotentialsMitochondria, HeartOxidative PhosphorylationOxygenRatsRats, WistarConceptsPhosphorylation systemPhosphorylation subsystemProton leakRat heart mitochondriaMitochondrial membrane potentialHeart mitochondriaIsolated rat heart mitochondriaOxidative phosphorylationRespiratory chainMitochondrial respirationStimulation of respirationSuccinate oxidationMembrane potentialPhosphorylationMitochondriaRespiration rateRespirationPhysiological concentrationsRespiratory subsystemState 3Ca2Free Ca2
1995
Calcium Indirectly Increases the Control Exerted by the Adenine Nucleotide Translocator over 2-Oxoglutarate Oxidation in Rat Heart Mitochondria
Mildaziene V, Baniene R, Nauciene Z, Bakker B, Brown G, Westerhoff H, Kholodenko B. Calcium Indirectly Increases the Control Exerted by the Adenine Nucleotide Translocator over 2-Oxoglutarate Oxidation in Rat Heart Mitochondria. Archives Of Biochemistry And Biophysics 1995, 324: 130-134. PMID: 7503547, DOI: 10.1006/abbi.1995.9918.Peer-Reviewed Original ResearchControl theory of metabolic channelling
Kholodenko B, Cascante M, Westerhoff H. Control theory of metabolic channelling. Molecular And Cellular Biochemistry 1995, 143: 151-168. PMID: 7596350, DOI: 10.1007/bf01816949.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsEnergy MetabolismEnzymesHumansMathematicsModels, BiologicalOxidative PhosphorylationSignal TransductionThermodynamicsConceptsControl theory
1993
Kinetic models of coupling between H+ and Na+-translocation and ATP synthesis/hydrolysis by F0F1-ATPases: Can a cell utilize both and for ATP synthesis underin vivo conditions using the same enzyme?
Kholodenko B. Kinetic models of coupling between H+ and Na+-translocation and ATP synthesis/hydrolysis by F0F1-ATPases: Can a cell utilize both and for ATP synthesis underin vivo conditions using the same enzyme? Journal Of Bioenergetics And Biomembranes 1993, 25: 285-295. PMID: 8394322, DOI: 10.1007/bf00762589.Peer-Reviewed Original Research
1989
The role of long-chain acyl-CoA in the disturbances of oxidative phosphorylation in the myocardium.
Borutaĭte V, Mildazhene V, Ivanovene L, Kholodenko B, Toleĭkis A, Prashkiavichius A. The role of long-chain acyl-CoA in the disturbances of oxidative phosphorylation in the myocardium. Биохимия 1989, 54: 1947-51. PMID: 2633800.Peer-Reviewed Original ResearchMeSH KeywordsAcyl Coenzyme AAdenosine DiphosphateAnimalsCreatine KinaseKineticsMitochondria, HeartMyocardiumOxidative PhosphorylationOxygen ConsumptionRabbitsThe role of long‐chain acyl‐CoA in the damage of oxidative phosphorylation in heart mitochondria
Borutait≐ V, Mildaz̆ien≐ V, Ivanovien≐ L, Kholodenko B, Toleikis A, Pras̆kevic̆ius A. The role of long‐chain acyl‐CoA in the damage of oxidative phosphorylation in heart mitochondria. FEBS Letters 1989, 243: 264-266. PMID: 2917650, DOI: 10.1016/0014-5793(89)80141-3.Peer-Reviewed Original Research
1988
The role of adenine nucleotide translocator in the regulation of oxidative phosphorylation in heart mitochondria.
Kholodenko B, Zhilinskene V, Borutaĭte V, Ivanovene L, Toleĭkis A. The role of adenine nucleotide translocator in the regulation of oxidative phosphorylation in heart mitochondria. Биохимия 1988, 53: 1009-12. PMID: 2846076.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsKineticsMitochondria, HeartMitochondrial ADP, ATP TranslocasesNucleotidyltransferasesOxidation-ReductionOxidative PhosphorylationPhosphocreatineRabbitsSuccinatesConceptsAdenine nucleotide translocaseOxidative phosphorylationNucleotide translocaseADP/ATP translocaseHeart mitochondriaATP translocaseTitration of respirationTranslocaseRegulatory rolePhosphorylationRabbit heart mitochondriaMitochondriaRespiration rateRole of adenineRegulationRespirationKey roleState 3TranslocatorRoleCarboxyatractylosideControl coefficientsADPHow do external parameters control fluxes and concentrations of metabolites? An additional relationship in the theory of metabolic control
Kholodenko B. How do external parameters control fluxes and concentrations of metabolites? An additional relationship in the theory of metabolic control. FEBS Letters 1988, 232: 383-386. PMID: 3378629, DOI: 10.1016/0014-5793(88)80775-0.Peer-Reviewed Original Research
1987
The role of adenine nucleotide translocators in regulation of oxidative phosphorylation in heart mitochondria
Kholodenko B, Z̆ilinskie·e V, Borutait·e V, Ivanovien·e L, Toleikis A, Pras̆kevic̆ius A. The role of adenine nucleotide translocators in regulation of oxidative phosphorylation in heart mitochondria. FEBS Letters 1987, 223: 247-250. PMID: 2822484, DOI: 10.1016/0014-5793(87)80298-3.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAtractylosideMitochondria, HeartMitochondrial ADP, ATP TranslocasesNucleotidyltransferasesOxidative PhosphorylationOxygen ConsumptionPhosphocreatineRabbitsConceptsAdenine nucleotide translocatorOxidative phosphorylationNucleotide translocatorHeart mitochondriaRespiration rateTitration of respirationPhosphorylationTranslocatorRabbit heart mitochondriaMitochondriaRegulative roleState 4RegulationKey roleState 3RoleCarboxyatractylosideRespirationControl coefficientsADP
1984
Control of mitochondrial oxidative phosphorylation
Kholodenko B. Control of mitochondrial oxidative phosphorylation. Journal Of Theoretical Biology 1984, 107: 179-188. PMID: 6717037, DOI: 10.1016/s0022-5193(84)80020-x.Peer-Reviewed Original ResearchMeSH KeywordsAdenosine DiphosphateAdenosine TriphosphateAnimalsKineticsLiverMathematicsMitochondria, LiverMitochondrial ADP, ATP TranslocasesOxidative PhosphorylationRats