2009
Positional Information Generated by Spatially Distributed Signaling Cascades
Muñoz-García J, Neufeld Z, Kholodenko BN. Positional Information Generated by Spatially Distributed Signaling Cascades. PLOS Computational Biology 2009, 5: e1000330. PMID: 19300504, PMCID: PMC2654021, DOI: 10.1371/journal.pcbi.1000330.Peer-Reviewed Original Research
2004
Quantitative analysis of signaling networks
Sauro H, Kholodenko B. Quantitative analysis of signaling networks. Progress In Biophysics And Molecular Biology 2004, 86: 5-43. PMID: 15261524, DOI: 10.1016/j.pbiomolbio.2004.03.002.Peer-Reviewed Original ResearchInferring dynamic architecture of cellular networks using time series of gene expression, protein and metabolite data
Sontag E, Kiyatkin A, Kholodenko BN. Inferring dynamic architecture of cellular networks using time series of gene expression, protein and metabolite data. Bioinformatics 2004, 20: 1877-1886. PMID: 15037511, DOI: 10.1093/bioinformatics/bth173.Peer-Reviewed Original Research
2000
Engineering a Living Cell to Desired Metabolite Concentrations and Fluxes: Pathways with Multifunctional Enzymes
Kholodenko B, Westerhoff H, Schwaber J, Cascante M. Engineering a Living Cell to Desired Metabolite Concentrations and Fluxes: Pathways with Multifunctional Enzymes. Metabolic Engineering 2000, 2: 1-13. PMID: 10935931, DOI: 10.1006/mben.1999.0132.Peer-Reviewed Original ResearchConceptsMultifunctional enzymeRest of metabolismMetabolic engineeringMetabolic control analysisCellular pathwaysCellular metabolismMolecular geneticsCellular enzymesLiving cellsEnzymeMetabolismPathwayGeneticsMachineryMetabolic patternsEnzyme concentrationSingle intermediateModulationCellsMetabolite concentrationsPatterns
1996
Effect of channelling on the concentration of bulk-phase intermediates as cytosolic proteins become more concentrated
KHOLODENKO B, WESTERHOFF H, CASCANTE C. Effect of channelling on the concentration of bulk-phase intermediates as cytosolic proteins become more concentrated. Biochemical Journal 1996, 313: 921-926. PMID: 8611176, PMCID: PMC1216999, DOI: 10.1042/bj3130921.Peer-Reviewed Original Research