Kinetics and control of oxidative phosphorylation in rat liver mitochondria after chronic ethanol feeding
MARCINKEVICIUTE A, MILDAZIENE V, CRUMM S, DEMIN O, HOEK J, KHOLODENKO B. Kinetics and control of oxidative phosphorylation in rat liver mitochondria after chronic ethanol feeding. Biochemical Journal 2000, 349: 519-526. DOI: 10.1042/bj3490519.Peer-Reviewed Original ResearchOxidative phosphorylationRespiratory fluxMitochondrial proton leakRat liver mitochondriaMitochondrial oxidative phosphorylationCytochrome c oxidaseMitochondrial energy metabolismATP synthaseLiver mitochondriaBc1 complexProton leakC oxidaseProtonmotive forceState 3PhosphorylationBlocks of reactionsEnergy metabolismMitochondriaMitochondrial malfunctioningRespiration rateRespiratory activityRespiratory subsystemIndividual functional unitsFunctional unitsLow activity