Direct Transfer of Control and Multidrug Resistance
Westerhoff H, Rohwer J, Heijn M, Mülder S, Ghauharali R, Wielinga P, Kholodenko B, Spoelstra E, Lankelma J. Direct Transfer of Control and Multidrug Resistance. NATO Science Series A: 1996, 283-292. DOI: 10.1007/978-1-4615-5845-3_29.Peer-Reviewed Original ResearchPhosphotransferase systemIntact cellsBacterial phosphotransferase systemPlasma membrane vesiclesCellular processesPTS enzymesSignal transductionPlasma membraneKinetic propertiesMultidrug pumpMembrane vesiclesIntracellular daunorubicin concentrationMultidrug resistanceIntricate organizationP-glycoproteinModel systemIntact systemDrug effluxDrug pumpCellsPassive permeabilityDirect transferTransductionDistribution of controlDNA