Aurora B controls anaphase onset and error-free chromosome segregation in trypanosomes
Ballmer D, Lou H, Ishii M, Turk B, Akiyoshi B. Aurora B controls anaphase onset and error-free chromosome segregation in trypanosomes. Journal Of Cell Biology 2024, 223: e202401169. PMID: 39196069, PMCID: PMC11354203, DOI: 10.1083/jcb.202401169.Peer-Reviewed Original ResearchConceptsAurora BAnaphase onsetMetaphase-to-anaphase transitionPromote mitotic exitComplex regulatory circuitryEarly-branching eukaryotesKinetochore-microtubule attachmentsAurora B activityDelays anaphase onsetAurora B kinaseCell cycle progressionSpindle assembly checkpointKinetochore proteinsMitotic exitOuter kinetochoreChromosome segregationChromosome missegregationRegulatory circuitrySpindle microtubulesAurora B inhibitionCycle progressionTrypanosoma bruceiAssembly checkpointB kinaseKinetochore