2024
Neutrophils insert elastase into hepatocytes to regulate calcium signaling in alcohol-associated hepatitis
Ogino N, Leite M, Guerra M, Kruglov E, Asashima H, Hafler D, Ito T, Pereira J, Peiffer B, Sun Z, Ehrlich B, Nathanson M. Neutrophils insert elastase into hepatocytes to regulate calcium signaling in alcohol-associated hepatitis. Journal Of Clinical Investigation 2024, 134: e171691. PMID: 38916955, PMCID: PMC11324315, DOI: 10.1172/jci171691.Peer-Reviewed Original ResearchAlcohol-associated hepatitisReduced cell proliferationCalcium channel expressionCalcium signaling mechanismsIntracellular calcium channelsCell proliferationRegulate calcium signalingNeutrophil extracellular trapsChannel expressionNeutrophil granule proteinsCalcium channelsNeutrophil infiltrationPatient specimensGranule proteasesMouse modelHealthy subjectsLiver diseaseExtracellular trapsCalcium signalingSerpin E2NeutrophilsElastase activityHepatitisTissue remodelingSignaling mechanisms
1996
Ligand-gated calcium channels inside and out
Striggow F, Ehrlich B. Ligand-gated calcium channels inside and out. Current Opinion In Cell Biology 1996, 8: 490-495. PMID: 8791458, DOI: 10.1016/s0955-0674(96)80025-1.Peer-Reviewed Original ResearchConceptsLigand-gated calcium channelsStore-operated channelsCalcium-permeable channelsIntracellular membranesFunctional characterizationPlasma membraneAllosteric mechanismAssociated proteinsTrisphosphate receptorCalcium releaseRyanodine receptorIntracellular storesIntracellular calciumCalcium channelsMembraneReceptorsProteinTypes of channelsInositolRelease
1990
Doxorubicin has biphasic effects on cardiac sarcoplasmic reticulum calcium channels in planar lipid bilayers
Borgatta L, Ondrias K, Kim H, Ehrlich B. Doxorubicin has biphasic effects on cardiac sarcoplasmic reticulum calcium channels in planar lipid bilayers. Journal Of Molecular And Cellular Cardiology 1990, 22: s29. DOI: 10.1016/0022-2828(90)91394-m.Peer-Reviewed Original Research
1988
Calcium Channels Incorporated into Planar Lipid Bilayers: Phenomenology, Pharmacology, and Phylogeny
Ehrlich B, Forte M. Calcium Channels Incorporated into Planar Lipid Bilayers: Phenomenology, Pharmacology, and Phylogeny. 1988, 33-41. DOI: 10.1007/978-1-4613-0975-8_3.Peer-Reviewed Original Research
1984
Voltage-Dependent Calcium Channels from Paramecium Cilia Incorporated into Planar Lipid Bilayers
Ehrlich B, Finkelstein A, Forte M, Kung C. Voltage-Dependent Calcium Channels from Paramecium Cilia Incorporated into Planar Lipid Bilayers. Science 1984, 225: 427-428. PMID: 6330895, DOI: 10.1126/science.6330895.Peer-Reviewed Original Research