2001
Effect of gonadotropin-releasing hormone agonists on monocyte chemotactic protein-1 production and macrophage infiltration in leiomyomatous uterus
Sozen I, Senturk L, Arici A. Effect of gonadotropin-releasing hormone agonists on monocyte chemotactic protein-1 production and macrophage infiltration in leiomyomatous uterus. Fertility And Sterility 2001, 76: 792-796. PMID: 11591415, DOI: 10.1016/s0015-0282(01)02378-0.Peer-Reviewed Original ResearchConceptsMonocyte chemotactic protein-1Leiomyomatous uterusMacrophage countGonadotropin-releasing hormone agonistDirect paracrine effectChemotactic protein-1 productionMCP-1 levelsChemotactic protein-1MCP-1 stainingCross-sectional studyMyometrium of womenMCP-1 expressionMonocyte chemotactic protein-1 productionMCP-1 protein expressionUniversity Medical CenterProtein-1 productionGnRH agonistHormone agonistMacrophage infiltrationMedical CenterMAIN OUTCOMEImmunohistochemical analysisLeiomyoma cellsParacrine effectsGnRHEstradiol regulates monocyte chemotactic protein-1 in human coronary artery smooth muscle cells: a mechanism for its antiatherogenic effect
Seli E, Selam B, Mor G, Kayisli U, Pehlivan T, Arici A. Estradiol regulates monocyte chemotactic protein-1 in human coronary artery smooth muscle cells: a mechanism for its antiatherogenic effect. Menopause The Journal Of The North American Menopause Society 2001, 8: 296-301. PMID: 11449089, DOI: 10.1097/00042192-200107000-00013.Peer-Reviewed Original ResearchConceptsHuman coronary artery smooth muscle cellsCoronary artery smooth muscle cellsArtery smooth muscle cellsMonocyte chemotactic protein-1Smooth muscle cellsChemotactic protein-1Recruitment of macrophagesMCP-1 expressionMCP-1 proteinMuscle cellsProtective effectProtein 1Arterial wallSelective estrogen receptor modulatorsCoronary smooth muscle cellsMCP-1 protein productionEstrogen's protective effectPhenol red-free mediumCharcoal-stripped calf serumProtein productionEstrogen receptor modulatorsPathogenesis of atherosclerosisReverse transcriptase-polymerase chain reactionNorthern blotLow-density lipoprotein
1999
Regulation of Monocyte Chemotactic Protein-1 Expression in Human Endometrial Stromal Cells by Integrin-Dependent Cell Adhesion1
Garcia-Velasco J, Seli E, Arici A. Regulation of Monocyte Chemotactic Protein-1 Expression in Human Endometrial Stromal Cells by Integrin-Dependent Cell Adhesion1. Biology Of Reproduction 1999, 61: 548-552. PMID: 10411539, DOI: 10.1095/biolreprod61.2.548.Peer-Reviewed Original ResearchConceptsCell adhesionExtracellular matrix connectionsActin cytoskeletonMCP-1 regulationGene expressionIntegrin activationECM substratesProtein secretionStromal cell adhesionCytochalasin DCell typesMCP-1 gene expressionNovel mechanismHuman endometrial stromal cellsMonocyte chemotactic protein-1 expressionProtein levelsIntegrinsProtein-1 expressionAdhesion matrixRegulationExpressionStromal cellsESC adhesionEndometrial stromal cellsCollagen IVRegulation of Monocyte Chemotactic Protein-1 Expression in Human Endometrial Stromal Cells by Estrogen and Progesterone1
Arici A, Senturk L, Seli E, Bahtiyar M, Kim G. Regulation of Monocyte Chemotactic Protein-1 Expression in Human Endometrial Stromal Cells by Estrogen and Progesterone1. Biology Of Reproduction 1999, 61: 85-90. PMID: 10377035, DOI: 10.1095/biolreprod61.1.85.Peer-Reviewed Original ResearchConceptsMCP-1 expressionEndometrial stromal cellsHuman endometrial stromal cellsMCP-1 levelsStromal cellsMacrophage migrationEstrogen levelsMCP-1 protein productionMonocyte chemotactic protein-1 expressionMCP-1 mRNA levelsChemotactic protein-1 expressionChemotactic protein-1Combination of E2Steroid hormone levelsProtein-1 expressionConcentration-dependent mannerEndometrial macrophagesMCP-1E2 treatmentHormone levelsSex steroidsEstradiol-17betaProgesteroneMRNA levelsProtein 1
1998
The effect of monocyte chemotactic protein 1 in intraperitoneal adhesion formation in a mouse model
Zeyneloglu H, Seli E, Senturk L, Gutierrez L, Olive D, Arici A. The effect of monocyte chemotactic protein 1 in intraperitoneal adhesion formation in a mouse model. American Journal Of Obstetrics And Gynecology 1998, 179: 438-443. PMID: 9731850, DOI: 10.1016/s0002-9378(98)70376-x.Peer-Reviewed Original ResearchExpression and Hormonal Regulation of Monocyte Chemotactic Protein-1 in Myometrium and Leiomyomata
Sozen I, Olive D, Arici A. Expression and Hormonal Regulation of Monocyte Chemotactic Protein-1 in Myometrium and Leiomyomata. Fertility And Sterility 1998, 69: 1095-1102. PMID: 9627299, DOI: 10.1016/s0015-0282(98)00072-7.Peer-Reviewed Original ResearchConceptsMCP-1 mRNA levelsChemotactic protein-1MCP-1Leiomyoma cellsSex steroidsHigher MCP-1 levelsSteroid hormonesMCP-1 protein productionMonocyte chemotactic protein-1MCP-1 levelsMRNA levelsProtein 1Proliferative phase samplesImmunoreactive MCP-1MCP-1 expressionUniversity Medical CenterLeiomyoma cell proliferationParacrine growth factorMCP-1 mRNAGrowth stimulatory effectMessenger RNA levelsPathogenesis of leiomyomaLocal immunityGnRH analoguesProspective study
1997
Monocyte chemotactic protein-1 concentration in peritoneal fluid of women with endometriosis and its modulation of expression in mesothelial cells
Arici A, Oral E, Attar E, Tazuke S, Olive D. Monocyte chemotactic protein-1 concentration in peritoneal fluid of women with endometriosis and its modulation of expression in mesothelial cells. Fertility And Sterility 1997, 67: 1065-1072. PMID: 9176445, DOI: 10.1016/s0015-0282(97)81440-9.Peer-Reviewed Original ResearchConceptsMonocyte chemotactic protein-1Chemotactic protein-1 levelsChemotactic protein-1Protein-1 levelsChemotactic protein-1 concentrationsProtein-1 concentrationsPeritoneal fluidMesothelial cellsPg/Severe endometriosisProtein 1Control womenSecretory phaseProliferative phaseSevere endometriosis groupPathogenesis of endometriosisPeritoneal mesothelial cellsInterleukin-1 alphaUniversity Medical CenterMessenger RNA expressionUntreated endometriosisGnRH agonistEndometriosis groupModerate endometriosisProspective studyMonocyte chemotactic protein-1 expression in human preovulatory follicles and ovarian cells
Arici A, Oral E, Bukulmez O, Buradagunta S, Bahtiyar O, Jones E. Monocyte chemotactic protein-1 expression in human preovulatory follicles and ovarian cells. Journal Of Reproductive Immunology 1997, 32: 201-219. PMID: 9080384, DOI: 10.1016/s0165-0378(97)82476-x.Peer-Reviewed Original ResearchConceptsMonocyte chemotactic protein-1MCP-1 levelsFollicular fluidHCG administrationPreovulatory folliclesPg/Granulosa-lutein cell culturesSerum MCP-1 levelsMacrophage migrationMCP-1 mRNA expressionChemotactic protein-1 expressionAdministration of hCGHuman preovulatory folliclesSerum progesterone levelsChemotactic protein-1Human ovarian folliclesFollicular fluid samplesHuman follicular fluidGranulosa-lutein cellsLH/hCGInterleukin-1 alphaMonocytes/macrophagesProtein-1 expressionMCP-1 mRNAPg/mL
1995
Regulation of monocyte chemotactic protein-1 gene expression in human endometrial cells in cultures
Arici A, MacDonald P, Casey M. Regulation of monocyte chemotactic protein-1 gene expression in human endometrial cells in cultures. Molecular And Cellular Endocrinology 1995, 107: 189-197. PMID: 7768330, DOI: 10.1016/0303-7207(94)03442-v.Peer-Reviewed Original ResearchMeSH KeywordsBase SequenceCells, CulturedChemokine CCL2Chemotactic FactorsCulture MediaDeciduaDNA PrimersEndometriumEpithelial CellsEpitheliumFemaleGene Expression RegulationHalf-LifeHumansInterleukin-1Menstrual CycleMolecular Sequence DataPlatelet-Derived Growth FactorPregnancyRNA, MessengerTranscription, GeneticTumor Necrosis Factor-alphaConceptsMCP-1 mRNAMonocyte chemotactic protein-1Endometrial stromal cellsEndometrium/deciduaStromal cellsBone marrow-derived leukocytesHuman endometrial stromal cellsEpithelial cellsChemotactic protein-1 gene expressionDuration of pregnancyChemotactic protein-1Human endometrial tissueMonocyte chemotactic protein-1 gene expressionHuman endometrial cellsHuman endometrium/deciduaDay of cycleProtein-1 gene expressionTotal RNAMacrophage chemotacticTypes of leukocytesEndometrial tissueHormonal milieuDecidua parietalisEndometrial cellsHuman endometrium