2010
Effect of the new legislation and single-embryo transfer policy in Turkey on assisted reproduction outcomes: preliminary results
Kutlu P, Atvar O, Vanlioglu O, Kutlu U, Arici A, Yilmaz S, Yilmaz E, Delikara N, Bener F, Kamar A, Alpak O, Ozekici U. Effect of the new legislation and single-embryo transfer policy in Turkey on assisted reproduction outcomes: preliminary results. Reproductive BioMedicine Online 2010, 22: 208-214. PMID: 21195669, DOI: 10.1016/j.rbmo.2010.10.007.Peer-Reviewed Original ResearchConceptsMultiple pregnancy ratePregnancy rateAge groupsSingle embryo transfer policyOverall populationClinical pregnancy rateSecond treatment cycleAssisted reproduction outcomesYears of ageNumber of embryosDifferent age groupsClinical pregnancyMulticentre studyMultiple pregnanciesReproduction treatmentTreatment cyclesReproduction outcomesOlder agePregnancyOutcomesFurther investigationSignificant declineFurther cyclesAgeGroup
2008
Cycle outcome can be predicted by the growth profile of untransferred cleavage-stage embryos
Yilmaz S, Kutlu P, Sofuoglu K, Delikara N, Kolankaya A, Arici A. Cycle outcome can be predicted by the growth profile of untransferred cleavage-stage embryos. Reproductive BioMedicine Online 2008, 16: 124-128. PMID: 18252058, DOI: 10.1016/s1472-6483(10)60565-2.Peer-Reviewed Original ResearchConceptsGroup 1Pregnancy outcomesPregnancy rateGroup 2Intracytoplasmic sperm injection cyclesAssisted reproduction treatment cyclesBlastocyst formationSperm injection cyclesCycle outcomeIVF unitReceiving treatmentTreatment cyclesDay 5Excess embryosCleavage stage embryosPatientsOutcomesInjection cyclesDevelopmental potentialExtended cultureEpidemiological factors influencing IVF outcome: Evidence from the Yale IVF program
Matalliotakis I, Cakmak H, Arici A, Goumenou A, Fragouli Y, Sakkas D. Epidemiological factors influencing IVF outcome: Evidence from the Yale IVF program. Journal Of Obstetrics And Gynaecology 2008, 28: 204-208. PMID: 18393021, DOI: 10.1080/01443610801912436.Peer-Reviewed Original ResearchConceptsIVF outcomesFamily historyEpidemiological factorsIVF-ET cyclesIVF-ET outcomeIVF-ET treatmentNon-pregnant womenMain outcome measuresMedical School HospitalDegree of smokingAge of womenIVF-ETInfertile womenMenstrual statusObstetric historyPregnant womenRetrospective studyIVF programMedical filesFertilization outcomeMedical historyInverse associationIVF unitMenstrual symptomsOutcome measures
2006
Long‐term pituitary down‐regulation before in vitro fertilization (IVF) for women with endometriosis
Sallam H, Garcia-Velasco J, Dias S, Arici A, Abou-Setta A, Jaafar S. Long‐term pituitary down‐regulation before in vitro fertilization (IVF) for women with endometriosis. Cochrane Database Of Systematic Reviews 2006, 2021: cd004635. PMID: 16437491, PMCID: PMC8195082, DOI: 10.1002/14651858.cd004635.pub2.Peer-Reviewed Original ResearchConceptsIntracytoplasmic sperm injectionNational Research RegisterGnRH agonistReview authorsPregnancy rateOdds ratioFourth review authorClinical pregnancy rateTubal factor infertilityCochrane Central RegisterThird review authorLive birth rateAdministration of gonadotrophinIndependent review authorsDegree of endometriosisEffect of administrationPrincipal outcome measureAdministration of GnRHLower pregnancy ratesMantel-Haenszel techniqueSpecialised RegisterClinical pregnancyEctopic pregnancyCentral RegisterMiscarriage rateAnatomic Factors in Recurrent Pregnancy Loss
Wold A, Pham N, Arici A. Anatomic Factors in Recurrent Pregnancy Loss. Seminars In Reproductive Medicine 2006, 24: 025-032. PMID: 16418975, DOI: 10.1055/s-2006-931798.Peer-Reviewed Original ResearchConceptsRecurrent pregnancy lossPregnancy lossPoor reproductive outcomesConsecutive spontaneous abortionsPreterm laborUterine anomaliesUterine defectUterine malformationsUterine septumIntrauterine adhesionsAbnormal presentationAnatomic abnormalitiesTreatment optionsAnatomic factorsSpontaneous abortionSurgical correctionReproductive outcomesAdequate treatmentCommon congenitalAccurate diagnosisContemporary diagnosisReproductive difficultiesDiagnosisWomenFibroids
2002
Structural Differentiation of Human Uterine Luminal and Glandular Epithelium during Early Pregnancy: An Ultrastructural and Immunohistochemical Study
Demir R, Kayisli U, Celik-Ozenci C, Korgun E, Demir-Weusten A, Arici A. Structural Differentiation of Human Uterine Luminal and Glandular Epithelium during Early Pregnancy: An Ultrastructural and Immunohistochemical Study. Placenta 2002, 23: 672-684. PMID: 12361686, DOI: 10.1053/plac.2002.0841.Peer-Reviewed Original ResearchConceptsGlandular epitheliumEarly pregnancyTrophoblastic invasionEarly gestationClear cellsDark cellsImmunoreactivity of PCNAEpithelial cellsEarly human pregnancyHuman endometrial epitheliumApocrine secretory activityEndothelial marker CD31Luminal epithelial cellsEarly gestation periodCell nuclear antigenHuman pregnancyEndometrial cellsMenstrual cycleImmunohistochemical studyEndometrial epitheliumLuminal epitheliumSurface epitheliumProminent nucleoliPregnancyUterine secretions
2001
Endometriosis and assisted reproductive technologies: are outcomes affected?
Mahutte N, Arici A. Endometriosis and assisted reproductive technologies: are outcomes affected? Current Opinion In Obstetrics & Gynecology 2001, 13: 275-279. PMID: 11396650, DOI: 10.1097/00001703-200106000-00005.Peer-Reviewed Original Research
2000
Empty follicle syndrome: evidence for recurrence
Zreik T, Garcia-Velasco J, Vergara T, Arici A, Olive D, Jones E. Empty follicle syndrome: evidence for recurrence. Human Reproduction 2000, 15: 999-1002. PMID: 10783341, DOI: 10.1093/humrep/15.5.999.Peer-Reviewed Original ResearchConceptsEmpty follicle syndromeDrug-related problemsChance of recurrenceAltered folliculogenesisDysfunctional folliculogenesisIVF cyclesIVF patientsFrustrating conditionRecurrencePatientsFuture reproductive performanceFolliculogenesisInfrequent eventReproductive performanceRare eventOocytesSyndromeEtiologyEndogenous LH surge detection versus administration of HCG to correctly time intrauterine insemination: which provides a better pregnancy rate?
Garcia-Velasco J, Arici A, Zreik T. Endogenous LH surge detection versus administration of HCG to correctly time intrauterine insemination: which provides a better pregnancy rate? Human Reproduction 2000, 15: 975-976. PMID: 10739853, DOI: 10.1093/humrep/15.4.975.Peer-Reviewed Original Research
1999
Is the endometrium or oocyte/embryo affected in endometriosis?
Garcia-Velasco J, Arici A. Is the endometrium or oocyte/embryo affected in endometriosis? Human Reproduction 1999, 14: 77-89. PMID: 10690803, DOI: 10.1093/humrep/14.suppl_2.77.Peer-Reviewed Original ResearchConceptsOocyte/embryo qualityEmbryo qualityInadequate luteal functionOocyte donation programEffect of endometriosisEndometrium of womenOvarian steroid productionSpontaneous abortion rateSpectrum of conditionsOocytes/embryosImplantation rateEctopic endometriumEutopic endometriumClinical studiesLuteal functionUltrasound studyEndometriosisEndometriumOocyte qualityBiochemical markersSteroid productionDonation programAbortion rateWomenInfertilityMacrophage derived growth factors m odulate Fas ligand expression in cultured endometrial stromal cells: a role in endometriosis
Garcia-Velasco J, Arici A, Zreik T, Naftolin F, Mor G. Macrophage derived growth factors m odulate Fas ligand expression in cultured endometrial stromal cells: a role in endometriosis. Molecular Human Reproduction 1999, 5: 642-650. PMID: 10381819, DOI: 10.1093/molehr/5.7.642.Peer-Reviewed Original ResearchMeSH KeywordsCell DifferentiationCells, CulturedChoriocarcinomaCulture Media, ConditionedEndometriumFas Ligand ProteinFemaleFibroblast Growth Factor 2Gene Expression RegulationHumansLeukemia, MyeloidLigandsMacrophagesMembrane GlycoproteinsPlatelet-Derived Growth FactorPregnancyStromal CellsTransforming Growth Factor betaTumor Cells, CulturedUterine NeoplasmsConceptsBasic fibroblast growth factorEndometrial stromal cellsGrowth factorFasL expressionStromal cellsImmune cellsEndometrial cellsCultured endometrial stromal cellsEndometrial stromal cell culturesRegurgitated endometrial cellsImmune privilege statusPro-inflammatory naturePlatelet-derived growth factorMacrophage-conditioned mediumDose-dependent mannerFas ligand expressionFas ligand interactionsFibroblast growth factorStromal cell culturesPeritoneal fluidImmune surveillanceMacrophage productsLigand expressionCertain cell populationsCell populationsProspective, randomized, crossover study to evaluate the benefit of human chorionic gonadotropin–timed versus urinary luteinizing hormone–timed intrauterine inseminations in clomiphene citrate–stimulated treatment cycles
Zreik T, Garcı́a-Velasco J, Habboosh M, Olive D, Arici A. Prospective, randomized, crossover study to evaluate the benefit of human chorionic gonadotropin–timed versus urinary luteinizing hormone–timed intrauterine inseminations in clomiphene citrate–stimulated treatment cycles. Fertility And Sterility 1999, 71: 1070-1074. PMID: 10360912, DOI: 10.1016/s0015-0282(99)00116-8.Peer-Reviewed Original ResearchConceptsPregnancy rateClomiphene citrateCrossover studyUltrasound monitoringUrinary LH levelsReproductive Medicine CenterMale factor infertilityOverall pregnancy rateHCG timingLeading follicleUnexplained infertilityLH levelsUrinary LHFactor infertilityIntrauterine inseminationMenstrual cycleInfertile couplesMAIN OUTCOMEMedicine CenterProtocol BProtocol ADay 3IUITreatment cyclesDay 10Chemokines and human reproduction
Garcı́a-Velasco J, Arici A. Chemokines and human reproduction. Fertility And Sterility 1999, 71: 983-993. PMID: 10360897, DOI: 10.1016/s0015-0282(99)00120-x.Peer-Reviewed Original ResearchConceptsChemotactic protein-1Interleukin-8Preterm laborCervical ripeningMonocyte chemotactic protein-1Endometrial stromal cell growthRole of chemokinesProtein 1Corpus luteum functionInterleukin-8 correlatesNew therapeutic strategiesAutocrine growth factorHuman reproductionStromal cell growthRelease of collagenaseExtracellular matrix remodelingPeritoneal fluidVillous placentaChemotactic cytokinesHuman endometriumMEDLINE searchFollicular developmentTherapeutic strategiesLeukocyte trafficChemokinesSex Steroids Mediate HOXA11 Expression in the Human Peri-Implantation Endometrium1
Taylor H, Igarashi P, Olive D, Arici A. Sex Steroids Mediate HOXA11 Expression in the Human Peri-Implantation Endometrium1. The Journal Of Clinical Endocrinology & Metabolism 1999, 84: 1129-1135. PMID: 10084606, DOI: 10.1210/jcem.84.3.5573.Peer-Reviewed Original ResearchConceptsHuman endometriumEndometrial developmentSex steroidsHuman endometrial developmentPeri-implantation endometriumMaintenance of pregnancyDose-responsive increaseAdult human endometriumTime of implantationMessenger RNA levelsProgesterone concentrationsEndometriumHOXA11 expressionPhysiologic rangeRNA levelsSteroidsPotential rolePregnancyImplantationEstrogenHOXA11ExpressionGene expressionSequential developmentNorthern analysis
1998
Adverse effects of hydrosalpinx on pregnancy rates after in vitro fertilization–embryo transfer
Zeyneloglu H, Arici A, Olive D. Adverse effects of hydrosalpinx on pregnancy rates after in vitro fertilization–embryo transfer. Fertility And Sterility 1998, 70: 492-499. PMID: 9757878, DOI: 10.1016/s0015-0282(98)00200-3.Peer-Reviewed Original ResearchConceptsIVF-ETOdds ratioPregnancy rateClinical pregnancy rateFertilization-embryo transferEffect of hydrosalpinxUniversity Medical CenterEstablishment of pregnancyClinical pregnancyImplantation rateET cyclesPregnancy lossHydrosalpinxMedical CenterMAIN OUTCOMEAbortion rateAdverse effectsReduced chanceConfidence intervalsMetaanalysisPregnancyPatientsTotalGroupTrialsFas‐Fas Ligand System‐Induced Apoptosis in Human Placenta and Gestational Trophoblastic Disease
Mor G, Gutierrez L, Eliza M, Kahyaoglu F, Arici A. Fas‐Fas Ligand System‐Induced Apoptosis in Human Placenta and Gestational Trophoblastic Disease. American Journal Of Reproductive Immunology 1998, 40: 89-94. PMID: 9764350, DOI: 10.1111/j.1600-0897.1998.tb00396.x.Peer-Reviewed Original ResearchConceptsGestational trophoblastic diseaseTrophoblastic diseaseFasL expressionImmunobiology of pregnancyMaternal immune responseMaternal immune toleranceMaternal-fetal interfaceReverse transcriptase-polymerase chain reactionTranscriptase-polymerase chain reactionNick-end labeling assayFas ligand expressionEnd-labeling assayPaternal alloantigensPathologic placentasImmune toleranceFetal antigensT cellsFas-FasLImmune responseNormal placentaLigand expressionPlacentaHuman placentaParaffin sectionsPathologic statesComparison of Intrauterine Insemination with Timed Intercourse in Superovulated Cycles with Gonadotropins: A Meta-analysis
Zeyneloglu H, Arici A, Olive D, Duleba A. Comparison of Intrauterine Insemination with Timed Intercourse in Superovulated Cycles with Gonadotropins: A Meta-analysis. Fertility And Sterility 1998, 69: 486-491. PMID: 9531883, DOI: 10.1016/s0015-0282(97)00552-9.Peer-Reviewed Original ResearchConceptsPregnancy rateUnexplained infertilityProspective studyOdds ratioHusband's spermCycles of IUIEnglish-language abstractsSuperovulated cyclesTimed intercourseSuperovulation cyclesIntrauterine inseminationCommon odds ratioMAIN OUTCOMEPatient's chanceAcademic centersIUIMeta-AnalysisGonadotropinConfidence intervalsIntercoursePatientsPregnancyInfertilitySpermMEDLINELeukemia Inhibitory Factor in Human Reproduction
Senturk L, Arici A. Leukemia Inhibitory Factor in Human Reproduction. American Journal Of Reproductive Immunology 1998, 39: 144-151. PMID: 9506212, DOI: 10.1111/j.1600-0897.1998.tb00346.x.Peer-Reviewed Original ResearchConceptsLeukemia inhibitory factorFallopian tubeMenstrual cycleHuman endometriumMenstrual cycle-dependent mannerInhibitory factorRole of LIFEffects of LIFHuman reproductionEndometrial LIF expressionMyeloid leukemic cell linesTime of implantationTime of ovulationLIF levelsOvulatory eventsLIF expressionInterleukin-6 familyStromal cell culturesEndometrial tissueInflammatory cytokinesLeukemic cell linesPeripheral neuronsPleiotropic cytokineSuccessful implantationOvarian follicles
1997
Expression of 11 beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) in the human fetal adrenal.
Freije W, Pezzi V, Arici A, Carr B, Rainey W. Expression of 11 beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) in the human fetal adrenal. Reproductive Sciences 1997, 4: 305-9. PMID: 9408886, DOI: 10.1016/s1071-5576(97)00066-x.Peer-Reviewed Original ResearchSonohysterography for screening in recurrent pregnancy loss
Keltz M, Olive D, Kim A, Arici A. Sonohysterography for screening in recurrent pregnancy loss. Fertility And Sterility 1997, 67: 670-674. PMID: 9093192, DOI: 10.1016/s0015-0282(97)81364-7.Peer-Reviewed Original ResearchConceptsRecurrent pregnancy lossPregnancy lossReproductive-aged womenUniversity referral centerConsecutive pregnancy lossesSonohysterographic findingsHysteroscopic findingsReferral centerProspective evaluationIntrauterine abnormalitiesUterine cavityVaginal sonographyBalloon catheterSonohysterographyCavitary defectsHysterosalpingographyPatientsSurgeryHysterosalpingogramSonohysterogramLaparoscopyCatheterSonographyAbnormalitiesSpecificity