2020
The Role of Medical Therapy for Menigniomas
Roque A, Omuro A. The Role of Medical Therapy for Menigniomas. 2020, 201-215. DOI: 10.1007/978-3-030-59558-6_13.Peer-Reviewed Original ResearchSystemic therapyProspective single-arm studyNatural historyCurrent NCCN guidelinesLower relapse rateMajority of patientsSingle-arm studySmall patient populationVaried outcome measuresNCCN guidelinesRefractory meningiomasRepeat surgerySurgical resectionSystemic treatmentLocal therapyMedical therapyProlong survivalRelapse rateSurgical optionsArm studyPatient populationSomatostatin analoguesGrade IGrade IIAntiangiogenic agents
2006
Chemotherapy for primary central nervous system lymphoma.
Omuro AM, Abrey LE. Chemotherapy for primary central nervous system lymphoma. Neurosurgical FOCUS 2006, 21: e12. PMID: 17134114, DOI: 10.3171/foc.2006.21.5.13.Peer-Reviewed Original ResearchConceptsPrimary central nervous system lymphomaCentral nervous system lymphomaHigh-dose methotrexateUse of chemotherapyNervous system lymphomaElderly patientsSystem lymphomaSuch elderly patientsMainstay of treatmentToxic regimensChemotherapy regimensCorticosteroid agentsYounger patientsPatient ageRelapse rateRandomized trialsDifferent regimensOptimal treatmentRecent trialsTreatment paradigmHigh riskChemotherapyEffective drugsSingle agentRegimens