2022
PP1cβ dephosphorylates cardiac myosin by MYPT‐dependent and independent mechanisms
Lee E, Liu Z, Nguyen N, Nairn A, Chang A. PP1cβ dephosphorylates cardiac myosin by MYPT‐dependent and independent mechanisms. The FASEB Journal 2022, 36 DOI: 10.1096/fasebj.2022.36.s1.r3877.Peer-Reviewed Original ResearchMyosin light chain phosphataseRegulatory light chainCardiac myosinSmooth muscleNormal cardiac functionMain catalytic subunitSmooth muscle contractionMyosin light chain kinaseMyosin phosphatase targetCardiac functionPP1cβLight chain kinaseCatalytic subunitAccessory subunitsConstitutive phosphorylationProtein stabilityLight chain phosphataseKnockout animalsMuscle contractionMuscle pathogenesisConditional knockoutCardiac muscle myosinCardiac myocytesCardiac musclePhosphatase activity
1985
Calcium-Regulated Protein Phosphorylation in Mammalian Brain
Walaas S, Nairn A. Calcium-Regulated Protein Phosphorylation in Mammalian Brain. 1985, 238-264. DOI: 10.1007/978-3-642-70070-5_12.Peer-Reviewed Original ResearchCentral nervous systemExcitation-secretion couplingNerve cell functionSkeletal muscle contractionPeripheral nervesGeneration of Ca2Nervous systemImportant intracellular messengerMammalian brainNeurotransmitter synthesisMuscle contractionProtein phosphorylationCell functionMammalian tissuesMitochondrial respirationIntracellular messengerEndocytotic phenomenonSecretory glandsIon channelsCa2NerveBrainGlycogenolysis