2016
Chapter 29 Regulation of Striatal Signaling by Protein Phosphatases
Girault J, Greengard P, Nairn A. Chapter 29 Regulation of Striatal Signaling by Protein Phosphatases. Techniques In The Behavioral And Neural Sciences 2016, 24: 583-607. DOI: 10.1016/b978-0-12-802206-1.00029-5.Peer-Reviewed Original ResearchSerine/threonine proteinProtein phosphatase regulationRegulation of proteinsPhosphatase regulationProtein phosphataseARPP-16Regulatory phosphoproteinsIntracellular signalingIntercellular communicationMedium spiny projection neuronsKey roleDARPP-32Major classesGenesRegulationSignalingProteinStriatal medium spiny projection neuronsSpecific setStriatal signalingPhosphoproteinRoleModulatory rolePhosphataseNeurons
2008
DARPP-32 Mediates the Actions of Multiple Drugs of Abuse
Svenningsson P, Nairn A, Greengard P. DARPP-32 Mediates the Actions of Multiple Drugs of Abuse. 2008, 3-16. DOI: 10.1007/978-0-387-76678-2_1.Peer-Reviewed Original ResearchPhosphorylation stateSerine/threonine protein phosphatasePP-1DARPP-32Threonine protein phosphataseState of phosphorylationProtein kinase A.Protein kinase AProtein phosphatasePhosphorylation sitesVirtue of regulationKinase AKey rolePhosphorylationThr34Potent inhibitorAdditional neurotransmittersCK2Ser97Behavioral responsesPhosphoproteinInhibitorsCK1Thr75Protein