Ischemic and bleeding outcomes in women treated with bivalirudin during percutaneous coronary intervention: A subgroup analysis of the Randomized Evaluation in PCI Linking Angiomax to Reduced Clinical Events (REPLACE)–2 trial
Chacko M, Lincoff AM, Wolski KE, Cohen DJ, Bittl JA, Lansky AJ, Tsuchiya Y, Betriu A, Yen MH, Chew DP, Cho L, Topol EJ. Ischemic and bleeding outcomes in women treated with bivalirudin during percutaneous coronary intervention: A subgroup analysis of the Randomized Evaluation in PCI Linking Angiomax to Reduced Clinical Events (REPLACE)–2 trial. American Heart Journal 2006, 151: 1032.e1-1032.e7. PMID: 16644331, DOI: 10.1016/j.ahj.2006.02.012.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryAnticoagulantsDrug Therapy, CombinationFemaleHemorrhageHeparinHirudinsHumansMaleMulticenter Studies as TopicMyocardial InfarctionMyocardial RevascularizationPeptide FragmentsPlatelet Glycoprotein GPIIb-IIIa ComplexRandomized Controlled Trials as TopicRecombinant ProteinsRetrospective StudiesRisk AssessmentSex FactorsConceptsPercutaneous coronary interventionIschemic end pointsComposite ischemic end pointsContemporary percutaneous coronary interventionGpIIb-IIIa blockadeEnd pointMajor bleedingCoronary interventionMyocardial infarctionSubgroup analysisProvisional glycoprotein IIb/IIIa blockadeGlycoprotein IIb/IIIa blockadeAccess site bleedingInherent bleeding riskPCI Linking AngiomaxCongestive heart failureSex-based subgroup analysisPrior revascularizationUrgent revascularizationBleeding riskMinor bleedingMore diabetesSite bleedingHeart failurePoor outcome