2021
Utility of expanded anterior column resection versus decompression-alone for local control in the management of carcinomatous vertebral column metastases undergoing adjuvant stereotactic radiotherapy
Pennington Z, Pairojboriboon S, Chen X, Sacino A, Elsamadicy AA, de la Garza Ramos R, Patel J, Elder BD, Kleinberg LR, Sciubba DM, Redmond KJ, Lo SL. Utility of expanded anterior column resection versus decompression-alone for local control in the management of carcinomatous vertebral column metastases undergoing adjuvant stereotactic radiotherapy. The Spine Journal 2021, 22: 835-846. PMID: 34718175, DOI: 10.1016/j.spinee.2021.10.016.Peer-Reviewed Original ResearchConceptsStereotactic body radiotherapyLong-term local controlLocal recurrenceLocal controlAnterior columnTumor pathologyCommon primary tumor typesSingle comprehensive cancer centerAdjuvant stereotactic radiotherapySpinal column metastasesVertebral Column MetastasesRetrospective cohort studyLocal control ratePrimary tumor typeLocal tumor recurrenceComprehensive cancer centerKaplan-Meier functionInvasive surgical techniquesEpidural removalAdjuvant radiotherapySurgical debulkingCohort studyDisease resectionSpinal metastasesTumor involvementDrivers of Readmission and Reoperation After Surgery for Vertebral Column Metastases
Patel J, Pennington Z, Hersh AM, Hung B, Schilling A, Antar A, Elsamadicy AA, de la Garza Ramos R, Lubelski D, Larry Lo SF, Sciubba DM. Drivers of Readmission and Reoperation After Surgery for Vertebral Column Metastases. World Neurosurgery 2021, 154: e806-e814. PMID: 34389529, DOI: 10.1016/j.wneu.2021.08.015.Peer-Reviewed Original ResearchConceptsCharlson Comorbidity IndexSpinal metastasis surgeryComprehensive cancer centerUnplanned reoperationMedical comorbiditiesMetastasis surgeryIndependent predictorsUnplanned readmissionWound infectionCancer CenterDrivers of readmissionsLonger index admissionsVertebral Column MetastasesBaseline laboratory valuesMultivariable logistic regressionLength of stayPopulation of adultsOutcomes of interestWound healing factorsComorbidity indexIndex admissionVenous thromboembolismLocal recurrenceSurgical morbidityMultivariable analysis
2020
Laser interstitial thermal therapy (LITT) vs. bevacizumab for radiation necrosis in previously irradiated brain metastases
Sujijantarat N, Hong CS, Owusu KA, Elsamadicy AA, Antonios JP, Koo AB, Baehring JM, Chiang VL. Laser interstitial thermal therapy (LITT) vs. bevacizumab for radiation necrosis in previously irradiated brain metastases. Journal Of Neuro-Oncology 2020, 148: 641-649. PMID: 32602021, DOI: 10.1007/s11060-020-03570-0.Peer-Reviewed Original ResearchConceptsLaser interstitial thermal therapyLonger overall survivalRadiation necrosisInterstitial thermal therapyBrain metastasesOverall survivalMedian volume decreaseMedian volume increaseBrain metastasis patientsPre-treatment patient characteristicsRetrospective chart reviewResultsTwenty-five patientsPre-treatment factorsBevacizumab patientsChart reviewMetastasis patientsLocal recurrencePatient characteristicsTreatment optionsTreatment responseBevacizumabPatientsLesional volumeThermal therapyStatistical significance