2016
Population pharmacokinetic (PK) analysis of laromustine, an emerging alkylating agent, in cancer patients
Nassar AF, Wisnewski AV, King I. Population pharmacokinetic (PK) analysis of laromustine, an emerging alkylating agent, in cancer patients. Xenobiotica 2016, 47: 394-407. PMID: 27440490, DOI: 10.1080/00498254.2016.1201703.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Agents, AlkylatingFemaleHumansHydrazinesMaleMiddle AgedModels, BiologicalProdrugsSulfonamidesConceptsPopulation pharmacokinetic analysisInter-patient variabilityPharmacokinetic analysisSignificant single-agent activitySingle-agent activityPopulation PK analysisVolume of distributionHigh inter-patient variabilityInter-occasion variabilityAlkylating agentCancer patientsTotal clearanceTotal body waterClinical trialsHematologic malignanciesPK analysisDosing cyclesOrgan functionSolid tumorsAntineoplastic alkylating agentCentral compartmentNONMEM analysisRapid clearancePatientsClearance
2002
Mouse Models of Diisocyanate Asthma
Redlich CA, Wisnewski AV, Gordon T. Mouse Models of Diisocyanate Asthma. American Journal Of Respiratory Cell And Molecular Biology 2002, 27: 385-390. PMID: 12356570, DOI: 10.1165/rcmb.f249.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements