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INFORMATION FOR

    Yale Pathology to Have Large Representation at USCAP Annual Meeting

    February 23, 2023

    Dozens of Pathologists Are Scheduled to Participate

    The Department of Pathology at Yale School of Medicine will have a strong representation at the 112th Annual Meeting of the United States and Canadian Academy of Pathology from March 11-16 in New Orleans.

    The schedule is packed with events. More than two dozen Yale pathologists will participate in presentations, long courses, short courses, poster sessions, platform sessions and other presentations. Here is a list of participants:

    Monday, March 13

    8:15 AM – 8:30 AM

    Platform Session

    IRF8 Is a Plasmacytoid Dendritic Cell Marker that can Differentiate Subcutaneous Panniculitis-Like T-cell Lymphoma from Lupus Erythematosus Panniculitis
    Presenting Author: Jahg Wong, MD. Other Authors: Simon Roy, MD, Jennifer McNiff, MD, Mina Xu, MD

    9:30 AM – 12:00 PM

    Stowell-Orbison Dermatopathology

    Presentation:

    Molecular, Clinical and Pathological Features of Melanoma with Pathogenic Germline Mutations: A Cohort from a Single Large Institute
    Haiming Tang, MD, PhD, Tong Sun, MD, PhD, Ernest F. Hidalgo-Cedeno, MD, Jingjing Jiao, MD, PhD, Hao Wu, MD, PhD, Minghao Zhong, MD, PhD

    Stowell-Orbison Gynecologic and Obstetric Pathology

    Presentations:

    KRAS Mutation in Endometrial Complex Mucinous Change is Associated with Concurrent or Subsequent Development of Atypical Endometrial Hyperplasia and Endometrial Carcinoma
    Austin McHenry, MD, Natalia Buza, MD, Pei Hui, MD, PhD

    Targetable HER2 Mutations in Gynecologic Malignancies: Clinicopathological Immunohistochemical and Molecular Correlations
    Padmini A. Manrai, MD, Austin McHenry, MD, Pei Hui, MD, PhD, Natalia Buza, MD

    Morphologic Features are Neither Sensitive Nor Specific for the Diagnosis of Fumarate Hydratase Deficient Leiomyoma: A Clinicopathologic Study of 99 Uterine Leiomyomas with Atypical Nuclei
    Na Niu, MD, Natalia Buza, MD, Pei Hui, MD, Tong Sun, MD, PhD

    Stowell-Orbison Liver Pathology

    Post-Infantile Giant Cell Hepatitis: What Determines a Poor Outcome
    Contributors include: Jingjing Jiao, MD, PhD, Xuchen Zhang, MD, PhD

    Stowell-Orbison Pulmonary, Mediastinal, Pleural and Peritoneal Pathology

    Desmoplasia, Decreased Lymphocyte Infiltration and Absence of EGFR Mutations in Brain Metastases from Patients with Lung Adenocarcinoma are Associated with Worse Overall Survival
    Darin Dolezal, MD, PhD, Muhammed Ahmed, MD, Rita Abi-Raad, MD, Sampada Chande, MD, Anna Arnal Estape, PhD, Noelia Vilarino, MD, Sarah Goldberg, MD, MPH, Veronica Chiang, MD, FAANS, Guoping Cai, MD, MS, Don Nguyen, PhD

    10:30 AM – 12:00 PM

    IM49: Biopsy Diagnosis of Hepatic Epithelial Tumors: Let’s Master the Challenges and Pitfalls
    Xuchen Zhang, MD, PhD

    Short Course 52: Roadmap to Cytoses: Guide to Navigating the Elevated Blood Count
    Mina Xu, MD

    1:00 PM – 4:30 PM

    Poster Session II

    Cytopathology

    Histologic Follow-Up Results in Women with Atypical Squamous Cells Cannot Exclude High-Grade Squamous Intraepithelial Lesion: A Comparison Between SurePath and ThinPrep Liquid-Based Preparations
    Mohammed Ahmed, MD, Darin Dolezal, MD, PhD, Uma Krishnamurti, MD, MBBS, PhD, Angelique Levi, MD, Guoping Cai, MD, MS, Rita Abi-Raad, MD

    GU Pathology

    Co-Inactivation of TP53 and RB1 is Necessary but not Sufficient for Small Cell Carcinoma Bladder Transformation from High-Grade Urothelial Carcinoma
    Deepika Kumar, MD, Juan Silva Campos, MD, Jeremy Mao, Yale Pathology Labs, Arnaud Augert, PhD, Tong Sun, MD, PhD, Peter Humphrey, MD, PhD, Minghao Zhong, MD, PhD

    Tuesday, March 14

    9:15 AM – 9:30 AM

    Hematopathology Platform Session

    Mutations in ASXL1 and/or TET2 Identify a Subset with Worse Outcomes in Patients with Blastic Plasmacytoid Dendritic Cell Neoplasms
    Mina Xu, MD, lead presenter with many other contributors, including Gauri Panse, MD

    Mediastinal, Pleural and Peritoneal Pathology Platform Session

    Characterization of Lung Cancer with Pathogenic Germline Variants
    Mohamed M.H. Kahila, MBBCh, Joanna Gibson, MD, PhD, Karin E. Finberg, MD, PhD, Zenta Walther, MD, PhD, Minghao Zhong, MD, PhD

    Gastrointestinal Pathology Platform Session

    11:15 AM – 11:30 AM

    Clinicopathologic Features of Gastrointestinal Tract Langerhans Cell Histiocytosis
    Authors include Xuchen Zhang, MD, PhD

    Poster Session III

    9:30 AM – 12:00 PM

    Autopsy and Forensics

    The Utility of Hospital Autopsy Examinations in Therapeutic Complication Fatalities
    Donald Turbiville, MD, John Sinard, MD, PhD, James R. Gill, MD, CT Office of Chief Medical Examiner, Harold Sanchez, MD

    Cardiovascular Pathology

    Microscopic Pattern and Distribution of Immune Checkpoint Inhibitor-Induced Myocarditis: A Series of 12 Autopsy Cases Ruhani Sardana, MD, Mayara Bearse, MD, Harold Sanchez, MD, He Wang, MD, PhD

    COVID-19 Infection Associated with Enhanced Coronary Arterial Inflammation and Atherosclerotic Plaque Complications Mayara Bearse, MD, Ruhana Sardana, MD, Harold Sanchez, MD, He Wang, MD, PhD

    Landscape of Primary and Secondary Tumors of the Pericardium and Pleura: A Single Institutional Review
    He Wang, MD, PhD, Haiming Tang, MD, PhD

    1:15 PM – 1:30 PM

    Liver Pathology

    Artificial Intelligence-Aided Steatosis Assessment in Donor Livers According to Banff Consensus Recommendations
    Jingjing Jiao, MD, PhD, Haiming Tang, MD, PhD, Xuchen Zhang, MD, PhD

    Poster Session IV

    1:00 PM – 4:30 PM

    Breast Pathology

    Clinicopathologic Features and Prognosis in Metastatic Recurrent Breast Carcinoma with ESR1 Genetic Abnormalities
    Jennifer Moreira-Dinzey, MD, Haiying Zhan, MD, PhD, Uma Krishnamurti, MD, MBBS, PhD, Malini Harigopal, MD, Yuanxin Liang, MD

    Gastrointestinal Pathology

    MYC Overexpression in IBD-Associated Dysplasia is Predictive of Low-Grade Conventional Polypoid Dysplasia Recurrence in IBD Patients
    Yuanxin Liang, MD, Minghao Zhong, MD, PhD, Dhanpat Jain, MD

    Pathobiology and Emerging Techniques

    Small Next-Generation Sequencing of Non-Coding Mutations in Monitor Urothelial Carcinoma in Urine Samples
    Jianhui Wang, PhD, Guangxiao Yang, PhD, JingLan Wang, PhD, Adebowale Adeniran, MD, Grace Zhao, PhD, Minghao Zhong, MD

    Wednesday, March 15

    8:00 AM – 12:00 PM

    *Short Course 38: A Smooth Ride into the Rocky Landscape of Uterine Smooth Muscle Neoplasia

    Natalia Buza, MD

    9:30 AM – 12:00 PM

    Poster Session V

    Cytology

    Diagnostic Yield of Pericardial Fluid Cytology is Superior to Pericardial Biopsy
    Mayara Bearse, MD, Haiming Tang, MD, PhD, Jocelyn Chandler, MD, He Wang, MD, PhD

    Gastrointestinal Pathology

    Metastatic Colorectal Carcinoma Molecular Testing: Choice of Next Generation Sequencing Panel
    Mayara Bearse, MD, Zenta Walther, MD, PhD, Michael Cecchini, MD, Joanna Gibson, MND, PhD

    Genetic Mutation Comparison of the Micropapillary Carcinoma Component with the Conventional Adenocarcinoma Component of Colorectal Carcinoma
    Mayara Bearse, MD, Guangxiao Yang, MD, PhD, Minghao Zhong, MD, PhD, Xuchen Zhang, MD, PhD

    Lymphoproliferative Disorders of the Small and Large Intestines Mimicking Inflammatory Conditions: A Comparison Study Ernest F. Hidalgo Cedeno, MD, Alexa Siddon, MD, Andrea L. Barbieri, MD, Haiming Tang, MD, PhD, Mayara Bearse, MD, ILKe Nalbantoglu, MD

    Gynecologic and Obstetric Pathology

    Utility of Beta-Catenin Immunohistochemistry in Evaluating Squamous Morules in Endometrial Biopsy and Curettage Specimens
    Padmini A. Manrai, MD, Ernest F. Hidalgo Cedeno, MD, Sarah Marie Davidson, MD, Natalia Buza, MD, Pei Hui, MD, PhD, Tong Sun, MD, PhD

    1:00 PM - 4:00

    Poster Session

    MDM2 Amplified Liposarcoma with Polysomy 12 Tends to Have Larger Tumor Volume and High Grade De-Differentiated Morphology
    Haiming Tang, MD, PhD, Minghao Zhong, MD, PhD, William Laskin, MD, and Hao Wu, MD, PhD

    INSM-1 Expression is Superior to Traditional Markers of Neuroendocrine Features in Breast Neoplasms with Neuroendocrine Features
     Roxanne Wadia MD, Reza Golestani MD PhD, Peter Podany MD, Jennifer Moreira-Dinzey MD, Tong Sun MD PhD, Uma Krishnamurti MD PhD, Malini Harigopal MD

    Cytomorphologic Features of Salivary Duct Carcinoma from Primary and Metastatic Sites
    Ernest F Hidalgo Cedeno, MD, Minhua Wang, MD, Rita Abi-Raad, MD, Shahram Saberi, MD, Manju L Prasad, MD, Guoping Cai, MD, Adebowale J. Adeniran, MD, Syed Gilani, MD.

    TRPS1 Expression in Cytology Specimens of Salivary Duct Carcinoma
    Minhua Wang, MD, Ernest F Hidalgo Cedeno, MD, Manju L Prasad, MD, Guoping Cai, MD, Adebowale J. Adeniran, MD, Syed Gilani, MD.

    1:30 PM – 3:00 PM

    IM16: When Morphology Meets Molecular in Myeloid Neoplasms Alexa Siddon, MD

    1:30 PM – 5:30 PM

    Short Course 60: Gestational Trophoblastic Disease: Essential Knowledge for Precision Diagnosis

    Natalia Buza, MD

    3:30 PM – 4:00 PM

    As part of a Long Course, Next Generation Pathology: Technological Advances in Anatomic Pathology, David Rimm, MD, PhD, presents on, High-Plex Assessment of Biomarkers in Tumors

    Thursday, March 16

    10:00 AM – 11:30 AM

    IM Course 28: Pitfalls and Look-Alikes in Ovarian Frozen Section Pathology 
    Natalia Buza, MD