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    Yale Insights in Cardiovascular Medicine: 2022

    December 18, 2022
    by Elisabeth Reitman

    Trending cardiovascular-related research from the Yale School of Medicine.

    Researchers from the Yale School of Medicine Section of Cardiovascular Medicine outline emerging areas of research in the cardiovascular medicine field. Current research topics include the drivers of COVID-19, clinical decision making, and health disparities. Note the results are based on Altmetric data.

    COVID-19

    Identification of driver genes for critical forms of COVID-19 in a deeply phenotyped young patient cohort

    Science Translational Medicine

    Co-author: Michael Simons


    2022 ACC Expert Consensus Decision Pathway on Cardiovascular Sequelae of COVID-19 in Adults: Myocarditis and Other Myocardial Involvement, Post-Acute Sequelae of SARS-CoV-2 Infection, and Return to Play 

    Journal of the American College of Cardiology (JACC)

    Co-author: Erica S. Spatz


    Excess Mortality in Massachusetts During the Delta and Omicron Waves of COVID-19

    JAMA: Journal of the American Medical Association

    Authors: Chengan Du, Chenxue Liang, Harlan Krumholz


    Uncoupling of all-cause excess mortality from COVID-19 cases in a highly vaccinated state

    Lancet Infectious Diseases

    Authors: Chengan Du, Chenxue Liang, Shu-Xia Li, Zhenqiu Lin, Harlan M. Krumholz

    The findings suggest that the mortality toll of the omicron variant of SARS-CoV-2 was neutralized in a state where vaccination is widespread, further strengthening the case for sensible public health tactics.

    Dr. Harlan M. Krumholz

    Peripheral Artery Disease and COVID-19 Outcomes: Insights from the Yale DOM-CovX Registry

    Current Problems in Cardiology

    Authors: Kim G.Smolderen, Megan Lee, Tanima Arora, Michael Simonov, Carlos Mena-Hurtado

    Clinical decision support & patient-focused information

    Nudging within learning health systems: next generation decision support to improve cardiovascular care

    European Heart Journal

    Co-author: Tariq Ahmad


    Renal effects of guideline-directed medical therapies in heart failure: a consensus document from the Heart Failure Association of the European Society of Cardiology

    European Journal of Heart Failure

    Co-author: Jeffrey M. Testani


    Analysis of Patient-Focused Information About Left Atrial Appendage Occlusion on US Hospital Web Pages

    JAMA Internal Medicine

    Authors: Erica S. Spatz, Joseph Ross 


    Left Atrial Appendage Occlusion Versus Oral Anticoagulation in Atrial Fibrillation A Decision Analysis

    Annals of Internal Medicine

    Co-author: James V. Freeman

    Health disparities & outcomes research

    Evaluation of Temporal Trends in Racial and Ethnic Disparities in Sleep Duration Among US Adults, 2004-2018

    JAMA Network Open

    Authors: Howard Forman, Karthik Murugiah, Brita Roy, Cesar Caraballo-Cordovez, Yuan Lu, Harlan M. Krumholz, Johanna Elumn, Marcella Smith, Jeph Herrin, Shiwani Mahajan

    Specifically, we found that over the 15 years we analyzed, Black people had the highest prevalence of both short sleep duration [fewer than 7 hours] and long sleep duration [more than 9 hours].

    Dr. César Caraballo-Cordovez

    Trends in 10-Year Outcomes Among Medicare Beneficiaries Who Survived an Acute Myocardial Infarction

    JAMA Cardiology

    Authors: Erica Leifheit, Harlan Krumholz, Yun Wang

    Basic science research

    Cellular recovery after prolonged warm ischaemia of the whole body

    Nature

    Authors: Robert Duckrow, Mario Skarica, Madhav Menon, Albert Sinusas, Stephanie Thorn, Nenad Sestan, Gregory Tietjen, Suel-Kee Kim, Anita Huttner, Hitten Zaveri, Sudhir Perincheri, Khadija Banu, David Andrijevic, Kevin Sheth