Yury Nikolaev, MSc, PhD
Postdoctoral Associate
Research & Publications
Biography
News
Coauthors
Selected Publications
- Molecular insights into the force-from-lipids gating of mechanosensitive channelsBavi N, Cox C, Nikolaev Y, Martinac B. Molecular insights into the force-from-lipids gating of mechanosensitive channels. Current Opinion In Physiology 2023, 36: 100706. DOI: 10.1016/j.cophys.2023.100706.
- 3D architecture and a bicellular mechanism of touch detection in mechanosensory corpuscleNikolaev Y, Ziolkowski L, Pang S, Li W, Feketa V, Xu C, Gracheva E, Bagriantsev S. 3D architecture and a bicellular mechanism of touch detection in mechanosensory corpuscle. Science Advances 2023, 9: eadi4147. PMID: 37703368, PMCID: PMC10499330, DOI: 10.1126/sciadv.adi4147.
- Human TRPV1 structure and inhibition by the analgesic SB-366791Neuberger A, Oda M, Nikolaev Y, Nadezhdin K, Gracheva E, Bagriantsev S, Sobolevsky A. Human TRPV1 structure and inhibition by the analgesic SB-366791. Nature Communications 2023, 14: 2451. PMID: 37117175, PMCID: PMC10147690, DOI: 10.1038/s41467-023-38162-9.
- Extracellular cap domain is an essential component of the TRPV1 gating mechanismNadezhdin KD, Neuberger A, Nikolaev YA, Murphy LA, Gracheva EO, Bagriantsev SN, Sobolevsky AI. Extracellular cap domain is an essential component of the TRPV1 gating mechanism. Nature Communications 2021, 12: 2154. PMID: 33846324, PMCID: PMC8041747, DOI: 10.1038/s41467-021-22507-3.
- Lamellar cells in Pacinian and Meissner corpuscles are touch sensorsNikolaev YA, Feketa VV, Anderson EO, Schneider ER, Gracheva EO, Bagriantsev SN. Lamellar cells in Pacinian and Meissner corpuscles are touch sensors. Science Advances 2020, 6: eabe6393. PMID: 33328243, PMCID: PMC7744075, DOI: 10.1126/sciadv.abe6393.
- CNGA3 acts as a cold sensor in hypothalamic neuronsFeketa VV, Nikolaev YA, Merriman DK, Bagriantsev SN, Gracheva EO. CNGA3 acts as a cold sensor in hypothalamic neurons. ELife 2020, 9: e55370. PMID: 32270761, PMCID: PMC7182431, DOI: 10.7554/elife.55370.
- Piezo2 Integrates Mechanical and Thermal Cues in Vertebrate MechanoreceptorsNikolaev Y, Zheng W, Gracheva E, Bagriantsev S. Piezo2 Integrates Mechanical and Thermal Cues in Vertebrate Mechanoreceptors. Biophysical Journal 2020, 118: 396a. DOI: 10.1016/j.bpj.2019.11.2254.
- Mammalian TRP Ion Channels are Insensitive to Membrane StretchNikolaev Y, Cox C, Ridone P, Rohde P, Cordero-Morales J, Vasquez V, Laver D, Martinac B. Mammalian TRP Ion Channels are Insensitive to Membrane Stretch. Biophysical Journal 2020, 118: 22a. DOI: 10.1016/j.bpj.2019.11.299.
- Chapter Three Cell membrane mechanics and mechanosensory transductionMartinac B, Nikolaev Y, Silvani G, Bavi N, Romanov V, Nakayama Y, Martinac A, Rohde P, Bavi O, Cox C. Chapter Three Cell membrane mechanics and mechanosensory transduction. 2020, 86: 83-141. PMID: 33837699, DOI: 10.1016/bs.ctm.2020.08.002.
- Piezo2 integrates mechanical and thermal cues in vertebrate mechanoreceptorsZheng W, Nikolaev YA, Gracheva EO, Bagriantsev SN. Piezo2 integrates mechanical and thermal cues in vertebrate mechanoreceptors. Proceedings Of The National Academy Of Sciences Of The United States Of America 2019, 116: 17547-17555. PMID: 31413193, PMCID: PMC6717272, DOI: 10.1073/pnas.1910213116.
- Mechanosensitivity of Ion ChannelsCranfield C, Kloda A, Nikolaev Y, Martinac A, Ridone P, Bavi N, Bavi O, Petrov E, Battle A, Nomura T, Rohde P, Nakayama Y, Rosholm K, Cox C, Baker M, Martinac B. Mechanosensitivity of Ion Channels. 2019, 1-11. DOI: 10.1007/978-3-642-35943-9_376-2.
- A Cross-Species Analysis Reveals a General Role for Piezo2 in Mechanosensory Specialization of Trigeminal Ganglia from Tactile Specialist BirdsSchneider ER, Anderson EO, Feketa VV, Mastrotto M, Nikolaev YA, Gracheva EO, Bagriantsev SN. A Cross-Species Analysis Reveals a General Role for Piezo2 in Mechanosensory Specialization of Trigeminal Ganglia from Tactile Specialist Birds. Cell Reports 2019, 26: 1979-1987.e3. PMID: 30784581, PMCID: PMC6420409, DOI: 10.1016/j.celrep.2019.01.100.
- Mammalian TRP ion channels are insensitive to membrane stretchNikolaev YA, Cox CD, Ridone P, Rohde PR, Cordero-Morales JF, Vásquez V, Laver DR, Martinac B. Mammalian TRP ion channels are insensitive to membrane stretch. Journal Of Cell Science 2019, 132: jcs238360. PMID: 31722978, PMCID: PMC6918743, DOI: 10.1242/jcs.238360.
- Tuning ion channel mechanosensitivity by asymmetry of the transbilayer pressure profileMartinac B, Bavi N, Ridone P, Nikolaev YA, Martinac AD, Nakayama Y, Rohde PR, Bavi O. Tuning ion channel mechanosensitivity by asymmetry of the transbilayer pressure profile. Biophysical Reviews 2018, 10: 1377-1384. PMID: 30182202, PMCID: PMC6233343, DOI: 10.1007/s12551-018-0450-3.
- Mechanosensitivity of Ion ChannelsCranfield C, Kloda A, Nikolaev Y, Martinac A, Ridone P, Bavi N, Bavi O, Petrov E, Battle A, Nomura T, Rohde P, Nakayama Y, Rosholm K, Cox C, Baker M, Martinac B. Mechanosensitivity of Ion Channels. 2018, 1-11. DOI: 10.1007/978-3-642-35943-9_376-1.
- Principles of Mechanosensing at the Membrane InterfaceBavi N, Nikolaev Y, Bavi O, Ridone P, Martinac A, Nakayama Y, Cox C, Martinac B. Principles of Mechanosensing at the Membrane Interface. 2017, 19: 85-119. DOI: 10.1007/978-981-10-6244-5_4.
- Adding dimension to cellular mechanotransduction: Advances in biomedical engineering of multiaxial cell-stretch systems and their application to cardiovascular biomechanics and mechano-signalingFriedrich O, Schneidereit D, Nikolaev Y, Nikolova-Krstevski V, Schürmann S, Wirth-Hücking A, Merten A, Fatkin D, Martinac B. Adding dimension to cellular mechanotransduction: Advances in biomedical engineering of multiaxial cell-stretch systems and their application to cardiovascular biomechanics and mechano-signaling. Progress In Biophysics And Molecular Biology 2017, 130: 170-191. PMID: 28647645, DOI: 10.1016/j.pbiomolbio.2017.06.011.
- Biophysical Factors that Promote Mechanically-Induced Action Potentials in Neocortical and Hippocampal Pyramidal NeuronsNikolaev Y, Dosen P, Laver D, Van Helden D, Hamill O. Biophysical Factors that Promote Mechanically-Induced Action Potentials in Neocortical and Hippocampal Pyramidal Neurons. Biophysical Journal 2016, 110: 349a. DOI: 10.1016/j.bpj.2015.11.1877.
- Mechanosensitivity of TRPC6 Ion Channel Reconstituted in the LiposomesNikolaev Y, Rohde P, Laver D, Martinac B. Mechanosensitivity of TRPC6 Ion Channel Reconstituted in the Liposomes. Biophysical Journal 2016, 110: 610a-611a. DOI: 10.1016/j.bpj.2015.11.3260.
- Lipid–protein interactions: Lessons learned from stressBattle A, Ridone P, Bavi N, Nakayama Y, Nikolaev Y, Martinac B. Lipid–protein interactions: Lessons learned from stress. Biochimica Et Biophysica Acta 2015, 1848: 1744-1756. PMID: 25922225, DOI: 10.1016/j.bbamem.2015.04.012.
- Single mechanically-gated cation channel currents can trigger action potentials in neocortical and hippocampal pyramidal neuronsNikolaev Y, Dosen P, Laver D, van Helden D, Hamill O. Single mechanically-gated cation channel currents can trigger action potentials in neocortical and hippocampal pyramidal neurons. Brain Research 2015, 1608: 1-13. PMID: 25765154, DOI: 10.1016/j.brainres.2015.02.051.
- Mechanosensitivity of TRPC6 Ion ChannelsNikolaev Y, Rohde P, Cox C, Laver D, Martinac B. Mechanosensitivity of TRPC6 Ion Channels. Biophysical Journal 2015, 108: 564a. DOI: 10.1016/j.bpj.2014.11.3088.