Sandra L Wolin MD, PhD

Professor of Cell Biology and of Molecular Biophysics and Biochemistry; Director, Yale Center for RNA Science and Medicine

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Microbiology | Molecular Cell Biology, Genetics and Development | Biochemistry, Biophysics and Structural Biology

Office of Student ResearchStem Cell Center, Yale: Transcriptional Regulation of Stem and Progenitor CellsRadiobiology & RadiotherapyCenter for RNA Science and Medicine, YaleCell Biology: Cell Biology of RNA; Developmental Cell Biology and Genetics | HTI | Molecular Biophysics and Biochemistry

Research Interests

Noncoding RNAs; RNA surveillance; RNA damage; Autoimmune disease; Environmental stress more...


  • M.D., Yale University, 1985
  • Ph.D., Yale University, 1985

Selected Publications

  • Eckwahl, M.J., Sim, S., Smith, D., Telesnitsky, A. and Wolin, S.L. (2015). A retrovirus packages host noncoding RNAs from a novel surveillance pathway. Genes and Development 29, 646-57.
  • Chen, X., Sim, S., Wurtmann, E.J., Feke, A. and Wolin, S.L. (2014). Bacterial noncoding Y RNAs are widespread and mimic tRNAs. RNA 20, 1715-24.
  • Chen, X., Taylor, D.W., Fowler, C.C., Galan, J.E., Wang, H.-W., Wolin, S.L. (2013). An RNA degradation machine sculpted by Ro autoantigen and noncoding RNA. Cell 153, 166-177.



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