Amy Marie Ahasic, MD, MPH, FCCP

Assistant Professor of Medicine (Pulmonary)

Research Interests

Aging; Critical Care; Delirium; Epidemiology; Obesity; Occupational Medicine; Respiratory Distress Syndrome, Adult; Sepsis; Environmental Medicine; Acute Lung Injury

Public Health Interests

Environmental Health; Genetic epidemiology; Obesity; Occupational Health; Respiratory Disease/Infections

Research Organizations

Occupational & Environmental Medicine

Pulmonary, Critical Care & Sleep Medicine: ICU Research Working Group

Extensive Research Description

My research interest centers around obesity and metabolic pathways in critical illness. Because of their impact on cardiac and pulmonary function, such pathways may affect risk and prognosis in critical illness. I focus on acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) and sepsis as common critical illness with systemic physiologic derangements and high morbidity and mortality. The relationship between obesity and ARDS is of particular interest. My current American Heart Association grant focuses on patient-oriented research of both phenotypic and genotypic markers relevant to metabolic pathways, including insulin-like growth factor (IGF) and adipokines, in acute lung injury.

I am also interested in the aging ICU population, and their functional and cognitive outcomes after critical illness. This extends to the cognitive-metabolic connection linking various metabolic phenomena such as obesity and insulin resistance to cognitive impairment and delirium, particularly in older adults. Delirium in the ICU is a common phenomenon for which age is a major risk factor, and its occurrence has significant impacts on morbidity and mortality.

Yale MICU Biorepository project: Principal Investigator on this initiative to collect clinical data and biologic specimens from a broad range of critically ill patients. We have enrolled approximately 700 patients to date.

Selected Publications

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Contact Info

Amy Marie Ahasic, MD, MPH, FCCP
Patient Care Locations
Winchester Chest ClinicFitkin Memorial Pavilion
789 Howard Avenue, Ste 2nd Floor

New Haven, CT 06519
Yale-New Haven Hospital
20 York Street

New Haven, CT 06510
Mailing Address
P.O. Box 208057
300 Cedar Street

New Haven, CT 06520-8057

ICU Research Working Group