Xilin Shen, PhD
Research Scientist in Radiology and Biomedical ImagingCards
About
Research
Publications
2026
Is the whole more than the sum of its parts? Considering global and local features of the connectome improves prediction of individuals and phenotypes
Riley S, Cheng A, Wang Y, Shen X, Dhamala E, Zhao Y, Holmes A, Constable R, Yip S. Is the whole more than the sum of its parts? Considering global and local features of the connectome improves prediction of individuals and phenotypes. Imaging Neuroscience 2026, 4: imag.a.1287. PMID: 42382505, PMCID: PMC13317015, DOI: 10.1162/imag.a.1287.Peer-Reviewed Original ResearchUsing connectome-based predictive models to reveal the systems standardized tests and clinical symptoms are reflecting
Samardzija A, Shen X, Luo W, Greene A, Mehta S, Tokoglu F, Arora J, Woods S, Katz R, Sanacora G, Srihari V, Scheinost D, Constable R. Using connectome-based predictive models to reveal the systems standardized tests and clinical symptoms are reflecting. Nature Communications 2026 PMID: 42303975, DOI: 10.1038/s41467-026-73941-0.Peer-Reviewed Original ResearchOptimizing functional connectivity scanning conditions for predicting autistic traits
Horien C, Mandino F, Greene A, Shen X, Powell K, Vernetti A, O’Connor D, Adkinson B, Tejavibulya L, McPartland J, Volkmar F, Chun M, Chawarska K, Lake E, Rosenberg M, Satterthwaite T, Scheinost D, Finn E, Constable R. Optimizing functional connectivity scanning conditions for predicting autistic traits. Nature Mental Health 2026, 4: 792-805. PMID: 42137910, PMCID: PMC13167459, DOI: 10.1038/s44220-026-00623-7.Peer-Reviewed Original Research
2025
Whole-brain functional connectivity predicts regional tau PET in preclinical Alzheimer’s disease
Abuwarda H, Trainer A, Horien C, Shen X, Moret S, Ju S, Constable R, Fredericks C. Whole-brain functional connectivity predicts regional tau PET in preclinical Alzheimer’s disease. Brain Communications 2025, 7: fcaf274. PMID: 40735265, PMCID: PMC12305425, DOI: 10.1093/braincomms/fcaf274.Peer-Reviewed Original ResearchSupervised brain node and network construction under voxel-level functional imaging
Xu W, Wang S, Gao S, Tian X, Tan C, Shen X, Luo W, Constable T, Li T, Zhao Y. Supervised brain node and network construction under voxel-level functional imaging. Imaging Neuroscience 2025, 3: imag.a.56. PMID: 40800928, PMCID: PMC12319940, DOI: 10.1162/imag.a.56.Peer-Reviewed Original ResearchYale Brain Atlas to interactively explore multimodal structural and functional neuroimaging data
Collins E, Chishti O, McGrath H, Obaid S, King A, Qiu E, Gabriel E, Shen X, Arora J, Papademetris X, Constable R, Spencer D, Zaveri H. Yale Brain Atlas to interactively explore multimodal structural and functional neuroimaging data. Frontiers In Network Physiology 2025, 5: 1585019. PMID: 40607320, PMCID: PMC12217586, DOI: 10.3389/fnetp.2025.1585019.Peer-Reviewed Original ResearchSimultaneous WF-Ca2+ and BOLD-fMRI reveals modality-specific and sex-based differences in prodromal Alzheimer’s disease
Mandino F, Shen X, Fredericks C, Strittmatter S, Lake E. Simultaneous WF-Ca2+ and BOLD-fMRI reveals modality-specific and sex-based differences in prodromal Alzheimer’s disease. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2025 DOI: 10.58530/2025/0828.Peer-Reviewed Original ResearchNeural activity underpins dynamic BOLD signals: findings from simultaneous wide-field fluorescent calcium imaging and fMRI.
Mandino F, Horien C, Shen X, Papademetris X, Keilholz S, Xu N, Lake E. Neural activity underpins dynamic BOLD signals: findings from simultaneous wide-field fluorescent calcium imaging and fMRI. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2025 DOI: 10.58530/2025/1012.Peer-Reviewed Original ResearchMultimodal identification of the mouse brain using simultaneous Ca2+ imaging and fMRI
Mandino F, Horien C, Shen X, Desrosiers-Grégoire G, Luo W, Markicevic M, Constable R, Papademetris X, Chakravarty M, Betzel R, Lake E. Multimodal identification of the mouse brain using simultaneous Ca2+ imaging and fMRI. Communications Biology 2025, 8: 665. PMID: 40287579, PMCID: PMC12033268, DOI: 10.1038/s42003-025-08037-4.Peer-Reviewed Original Research
2024
Repetitive Mild Closed-Head Injury Induced Synapse Loss and Increased Local BOLD-fMRI Signal Homogeneity
Markicevic M, Mandino F, Toyonaga T, Cai Z, Fesharaki-Zadeh A, Shen X, Strittmatter S, Lake E. Repetitive Mild Closed-Head Injury Induced Synapse Loss and Increased Local BOLD-fMRI Signal Homogeneity. Journal Of Neurotrauma 2024, 41: 2528-2544. PMID: 39096127, PMCID: PMC11698675, DOI: 10.1089/neu.2024.0095.Peer-Reviewed Original Research
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