Michael Grant, MD
Assistant Professor of Medicine (Medical Oncology)Cards
About
Research
Overview
Medical Research Interests
Carcinoma, Non-Small-Cell Lung; Circulating Tumor DNA; Clinical Trial; Drug Resistance; Immunotherapy; Molecular Targeted Therapy; Small Cell Lung Carcinoma; Translational Research, Biomedical
Publications
2024
Preoperative medication management turnkey order set for nonemergent adult cardiac surgery
Rea A, Salenger R, Grant M, Yeh J, Damas B, Crisalfi C, Arora R, Gregory A, Morton-Bailey V, Engelman D, Group E, Cangut B, Chatterjee S, Lobdell K, McConnell G, Crotwell S, Reddy S. Preoperative medication management turnkey order set for nonemergent adult cardiac surgery. JTCVS Open 2024, 22: 1-13. DOI: 10.1016/j.xjon.2024.06.009.Peer-Reviewed Original ResearchSodium-glucose co-transporter-2Adult cardiac surgeryPreoperative medical managementGlucagon-like peptide-1Cardiac surgeryConsensus manuscriptNon-emergent cardiac surgeryMedical managementClass ICardiac surgical patientsCardiac surgical proceduresRisk of bleedingExpert consensus documentPreoperative managementPreoperative medicationsAnticoagulant medicationSurgical patientsSurgical proceduresSurgeryAnti-plateletPeptide-1Perioperative careConsensus documentCardiac SocietyManagement of patients' medicationPractice Advisory for Postoperative Pain Management of Thoracic Surgical Patients - A Report by Society of Cardiovascular Anesthesiologists
Makkad B, Heinke T, Sheriffdeen R, Meng M, Kachulis B, Grant M, Popescu W, Brodt J, Khatib D, Wu C, Kertai M, Bollen B. Practice Advisory for Postoperative Pain Management of Thoracic Surgical Patients - A Report by Society of Cardiovascular Anesthesiologists. Journal Of Cardiothoracic And Vascular Anesthesia 2024 DOI: 10.1053/j.jvca.2024.12.004.Peer-Reviewed Original ResearchPostoperative pain managementThoracic surgeryPain managementRisk of postoperative respiratory complicationsPersistent post-thoracotomy painPost-thoracotomy painThoracic surgical patientsPostoperative respiratory complicationsAcute pain managementClearance of secretionsPain management decisionsSociety of Cardiovascular AnesthesiologistsNon-pharmacological therapiesOpioid useAcute painMultimodal analgesiaRespiratory complicationsPharmacological therapySurgical patientsNormal respiratory mechanicsQuality of lifeOpioidSurgeryPainRespiratory mechanicsPractice Advisory for Postoperative Pain Management of Thoracic Surgical Patients: Executive Summary: A Report by Society of Cardiovascular Anesthesiologists
Makkad B, Heinke T, Sheriffdeen R, Meng M, Kachulis B, Grant M, Popescu W, Brodt J, Khatib D, Wu C, Kertai M, Bollen B. Practice Advisory for Postoperative Pain Management of Thoracic Surgical Patients: Executive Summary: A Report by Society of Cardiovascular Anesthesiologists. Journal Of Cardiothoracic And Vascular Anesthesia 2024 DOI: 10.1053/j.jvca.2024.12.003.Peer-Reviewed Original ResearchThoracic surgical patientsPostoperative pain managementPostoperative painPain controlSurgical populationSurgical patientsOpioid-related side effectsRisk of respiratory complicationsPersistent postoperative painPre-existing co-morbiditiesPractice advisorySociety of Cardiovascular AnesthesiologistsAnalgesic regimenRespiratory complicationsSignificant painPerioperative providersPain managementCo-morbiditiesNormal respiratory mechanicsPainSide effectsImpaired recoveryRespiratory mechanicsPatientsCardiovascular AnesthesiologistsEnhanced Recovery After Surgery (ERAS) cardiac turnkey order set for perioperative pain management in cardiac surgery: Proceedings from the American Association for Thoracic Surgery (AATS) ERAS Conclave 2023
Gregory A, Arora R, Chatterjee S, Crisafi C, Morton-Bailey V, Rea A, Salenger R, Engelman D, Grant M, Group E, Cangut B, Crotwell S, Lobdell K, McConnell G, Reddy S. Enhanced Recovery After Surgery (ERAS) cardiac turnkey order set for perioperative pain management in cardiac surgery: Proceedings from the American Association for Thoracic Surgery (AATS) ERAS Conclave 2023. JTCVS Open 2024, 22: 14-24. DOI: 10.1016/j.xjon.2024.08.018.Peer-Reviewed Original ResearchPerioperative pain managementCardiac surgeryPain managementOpioid administrationOptimal perioperative pain managementOpioid-related adverse eventsClass IShort-acting synthetic opioidLong-acting opioidsCardiac surgical patientsControl post-operativelyNon-steroidal anti-inflammatory drugsAssociated with delayed recoveryLong-term adverse effectsOpioid-based analgesiaEvidence-based order setsOpioid-sparing medicationsAnti-inflammatory drugsComprehensive multimodal approachExpert consensus documentRate of postoperative recoveryOpioid reductionInadequate analgesiaIntravenous analgesicsPost-operativelyPractice Advisory on the Implementation of Preoperative Anemia Management: The Society of Cardiovascular Anesthesiologists and the Society for the Advancement of Patient Blood Management.
Klompas A, Hensley N, Burt J, Grant M, Guinn N, Patel P, Popescu W, Raphael J, Salenger R, Shore-Lesserson L, Warner M. Practice Advisory on the Implementation of Preoperative Anemia Management: The Society of Cardiovascular Anesthesiologists and the Society for the Advancement of Patient Blood Management. Anesthesia & Analgesia 2024 PMID: 39671507, DOI: 10.1213/ane.0000000000007321.Peer-Reviewed Original ResearchPatient blood managementAdvancement of Patient Blood ManagementBlood managementPreoperative anemiaCardiac surgeryAnemia managementRed blood cell transfusionAssociated with worse outcomesPreoperative anemia clinicPatient blood management programBlood cell transfusionAcute kidney injuryBlood management programPreoperative anemia managementImproving clinical outcomesSociety of Cardiovascular Anesthesiologists (SCASociety of Cardiovascular AnesthesiologistsAnemia programCell transfusionAnemia clinicEducation of patientsAllogeneic transfusionCardiovascular complicationsKidney injuryTreatment algorithmPreoperative Multivariable Model for Risk Stratification of Hypoxemia During One-Lung Ventilation
Zorrilla-Vaca A, Grant M, Mendez-Pino L, Rehman M, Sarin P, Nasra S, Varelmann D. Preoperative Multivariable Model for Risk Stratification of Hypoxemia During One-Lung Ventilation. Anesthesia & Analgesia 2024 DOI: 10.1213/ane.0000000000007306.Peer-Reviewed Original ResearchOne-lung ventilationArea under the receiver operating curveRisk of hypoxemiaIntraoperative hypoxemiaRisk stratificationClinical variablesRisk of intraoperative hypoxemiaEpisodes of oxygen desaturationBody mass index >Preoperative clinical variablesStratification modelLung perfusion scanElective lung surgeryLateral decubitus positionPositive predictive valueRetrospective cohort studyCongestive heart failureHighest Youden indexPreoperative multivariable modelLogistic regressionRisk stratification modelRight-sided surgeryMultivariate logistic regressionIncidence of hypoxemiaDouble lumen tubeReturn on Investment of Preoperative Anemia Management Programs in Cardiac Surgery: An Advisory From the Society of Cardiovascular Anesthesiologists Clinical Practice Improvement Committee With Endorsement by the Society for the Advancement of Patient Blood Management.
Warner M, Ferreira R, Raphael J, Shore-Lesserson L, Grant M, Sykes Hill S, Morewood G, Popescu W, Schwann N, Guinn N. Return on Investment of Preoperative Anemia Management Programs in Cardiac Surgery: An Advisory From the Society of Cardiovascular Anesthesiologists Clinical Practice Improvement Committee With Endorsement by the Society for the Advancement of Patient Blood Management. Anesthesia & Analgesia 2024 PMID: 39671509, DOI: 10.1213/ane.0000000000006721.Peer-Reviewed Original ResearchAdvancement of Patient Blood ManagementPatient blood managementCardiac surgeryBlood managementElective cardiac surgeryTreatment of anemiaSociety of Cardiovascular Anesthesiologists (SCAPreoperative anemiaNoncardiac surgerySurgeryAnemiaLeadership buy-inFinancial modelManagement programsFinancial shortfallsFinancial implicationsCardiacBuy-inClinicDiagnosisImpact of Nighttime Cardiovascular Intensive Care Unit Staffing on Failure to Rescue and Revenue
Kang J, Holmes S, Rando H, Chinedozi I, Darby Z, Briscoe J, Grant M, Whitman G. Impact of Nighttime Cardiovascular Intensive Care Unit Staffing on Failure to Rescue and Revenue. The Annals Of Thoracic Surgery 2024 PMID: 39481824, DOI: 10.1016/j.athoracsur.2024.10.014.Peer-Reviewed Original ResearchEra 1Era 2Cardiac surgeryRelative value unitsFTR ratesPost-cardiotomy patientsMajor complicationsComplication ratePostoperative complicationsAnnual relative value unitsMultivariate analysisNighttime intensivist staffingComplicationsIntensive care unit staffingPatientsIntensivist staffingICU censusSurgeryICUMortalityValue unitsFiscal yearRiskUnit staffingFTRAvoiding the Things That Can Go Bump in The Night After Cardiac Surgery
Grant M, Arora R. Avoiding the Things That Can Go Bump in The Night After Cardiac Surgery. The Annals Of Thoracic Surgery 2024 PMID: 39442907, DOI: 10.1016/j.athoracsur.2024.09.050.Peer-Reviewed Original ResearchPractice Advisory for Postoperative Pain Management of Cardiac Surgical Patients: Executive Summary: A Report by Society of Cardiovascular Anesthesiologists
Makkad B, Heinke T, Sheriffdeen R, Meng M, Kachulis B, Grant M, Popescu W, Brodt J, Khatib D, Wu C, Kertai M, Bollen B. Practice Advisory for Postoperative Pain Management of Cardiac Surgical Patients: Executive Summary: A Report by Society of Cardiovascular Anesthesiologists. Journal Of Cardiothoracic And Vascular Anesthesia 2024 PMID: 39551694, DOI: 10.1053/j.jvca.2024.10.015.Peer-Reviewed Original ResearchCardiac surgical patientsTreat postoperative painCardiac surgeryPostoperative painMultimodal analgesiaSurgical patientsAssociated with significant postoperative painManagement of cardiac surgical patientsImproving postoperative pain reliefOpioid-associated side effectsEra of enhanced recoveryHigh dose opioidsSignificant postoperative painPain-related outcomesPostoperative pain reliefFascial plane blocksCo-existing morbiditiesPostoperative pain managementPractice advisorySociety of Cardiovascular AnesthesiologistsEvidence-based recommendationsDose opioidsOptimal analgesiaPlane blockPain relief
Clinical Care
Overview
Michael Grant, MD, is a medical oncologist and hematologist who cares for patients affected by cancer and other hematologic conditions, focusing on thoracic and genitourinary malignancies.
“I was inspired to become a doctor because I like people,” Dr. Grant says. “It is a unique privilege to be able to help people at a potentially vulnerable time, when they are facing challenges they may have never faced before. Medical oncology and hematology are two disciplines in which forming interpersonal relationships and building trust are vital.”
The field of oncology is advancing constantly, making it crucial for physicians to keep their practice up to standard, Dr. Grant says, and this has helped shaped his own approach. “I am passionate about personalized care, leveraging molecular features of a patient's cancer to choose the best treatment for that individual. This involves comprehensively testing for all available ‘biomarkers’ so that each treatment decision is maximally informed. In order to fulfill this commitment, I conduct research, build connections with other experts, and work diligently keep up with the latest advances in the field.”
An assistant professor of medical oncology at Yale School of Medicine, Dr. Grant’s research interests include targeted and immunotherapy approaches to the treatment of non-small cell lung cancer.
Clinical Specialties
Medical Oncology
Fact Sheets
Small Cell Lung Cancer
Learn More on Yale MedicineNon-Small Cell Lung Cancer
Learn More on Yale MedicineUrologic Cancers
Learn More on Yale MedicineLung Cancer
Learn More on Yale Medicine
Board Certifications
Medical Oncology
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2023
Internal Medicine
- Certification Organization
- AB of Internal Medicine
- Original Certification Date
- 2019
Yale Medicine News
News & Links
News
- November 14, 2024
Understanding Lung Cancer: A Conference to Raise Awareness and Offer Hope to Those Impacted by Lung Cancer
- December 13, 2022Source: ASCO Daily News
Emerging Treatment Options in the Management of Resistance to Tyrosine Kinase Inhibitors in Non–Small Cell Lung Cancer
- December 04, 2022
Why Some Lung Tumors Respond Better to Targeted Therapies Than Others
- September 07, 2022
Smilow Cancer Hospital in Waterbury Welcomes Dr. Michael Grant
Get In Touch
Contacts
Appointment Number
Locations
Patient Care Locations
Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.