Francine Testa, MD
Professor of Clinical PediatricsDownloadHi-Res Photo
About
Titles
Professor of Clinical Pediatrics
Clinical Professor of Pediatrics and Neurology
Biography
Clinical Pediatric Neurology with special expertise in clinical neurophysiology and epilepsy
Education & Training
- Fellow
- Neurological Institute of NY, Columbia-Presbyterian Hospital (1992)
- Resident
- Neurological Institute of NY, Columbia-Presbyterian Hospital (1991)
- Resident
- Neurological Institute of NY, Columbia-Presbyterian Hospital (1989)
- Resident
- Yale-New Haven Hospital (1988)
- MD
- SUNY Downstate Medical Center (1986)
Board Certifications
Neurology
- Certification Organization
- AB of Psychiatry & Neurology
- Original Certification Date
- 1994
Clinical Neurophysiology
- Certification Organization
- American Board of Clinical Neurophysiology, Inc.
- Original Certification Date
- 1993
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Francine Testa's published research.
Publications Timeline
A big-picture view of Francine Testa's research output by year.
Lawrence Hirsch, MD
Richard Bronen, MD
Susan Levy, MD
20Publications
1,773Citations
Publications
2020
Novel Mitochondrial Translation Optimizer-1 Mutations as a Cause of Hereditary Optic Neuropathy.
Li E, Emmanuele V, Testa F, Moreno CAM, Hirano M, Lesser RL. Novel Mitochondrial Translation Optimizer-1 Mutations as a Cause of Hereditary Optic Neuropathy. Journal Of Neuro-ophthalmology : The Official Journal Of The North American Neuro-Ophthalmology Society 2020, 40: 406-410. PMID: 31842146, DOI: 10.1097/WNO.0000000000000858.Peer-Reviewed Original Research
2018
Evolution and course of early life developmental encephalopathic epilepsies: Focus on Lennox‐Gastaut syndrome
Berg AT, Levy SR, Testa FM. Evolution and course of early life developmental encephalopathic epilepsies: Focus on Lennox‐Gastaut syndrome. Epilepsia 2018, 59: 2096-2105. PMID: 30255934, PMCID: PMC6215498, DOI: 10.1111/epi.14569.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsLennox-Gastaut syndromeInitial presentationMedian onset ageChi-square testRefractory seizuresCentral reviewEpilepsy syndromesInfantile spasmsEncephalopathic epilepsyMedical recordsOnset ageEarly deathEpilepsySyndromeCognitive outcomesConnecticut StudyLongitudinal studyT-testSeizuresChildrenPresentationSpasmStatistical analysisYearsMortality
2017
Surgical outcome in adolescents with mesial temporal sclerosis: Is it different?
Farooque P, Hirsch L, Levy S, Testa F, Mattson R, Spencer D. Surgical outcome in adolescents with mesial temporal sclerosis: Is it different? Epilepsy & Behavior 2017, 69: 24-27. PMID: 28235653, DOI: 10.1016/j.yebeh.2016.10.028.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMesial temporal sclerosisTemporal sclerosisStatus epilepticusTemporal lobectomySurgical outcomesAdolescent patientsIctal onsetMore lobesEpilepsy surgery databaseScalp EEGSeizure freedomPatient populationSurgery DatabaseRisk factorsPatientsElectrographic dataLobectomyEpilepticusTwo yearsSclerosisHypometabolismNovel findingsAdolescentsMRIOutcomes
2016
Determinants of Social Outcomes in Adults With Childhood-onset Epilepsy
Berg AT, Baca CB, Rychlik K, Vickrey BG, Caplan R, Testa FM, Levy SR. Determinants of Social Outcomes in Adults With Childhood-onset Epilepsy. Pediatrics 2016, 137: e20153944. PMID: 26983470, PMCID: PMC4811319, DOI: 10.1542/peds.2015-3944.Peer-Reviewed Original ResearchCitationsAltmetric
2014
Complete remission of childhood-onset epilepsy: stability and prediction over two decades
Berg AT, Rychlik K, Levy SR, Testa FM. Complete remission of childhood-onset epilepsy: stability and prediction over two decades. Brain 2014, 137: 3213-3222. PMID: 25338950, PMCID: PMC4240301, DOI: 10.1093/brain/awu294.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsComplete remissionSeizure resolutionSeizure outcomeInitial diagnosisChildhood epilepsyLast contactCourse of epilepsyChildhood-onset epilepsySelf-limited epilepsy syndromeProportional hazards modelProspective cohortBaseline factorsRelapse rateLate remissionEpilepsy syndromesComplete resolutionRemissionHazards modelPredictive valueEpilepsyLogistic regressionConnecticut StudyDiagnosisFurther treatmentDevelopmental problemsLong‐term seizure remission in childhood absence epilepsy: Might initial treatment matter?
Berg AT, Levy SR, Testa FM, Blumenfeld H. Long‐term seizure remission in childhood absence epilepsy: Might initial treatment matter? Epilepsia 2014, 55: 551-557. PMID: 24512528, PMCID: PMC3999182, DOI: 10.1111/epi.12551.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsChildhood absence epilepsyComplete remissionAtypical EEG featuresValproic acidEarly remissionAbsence epilepsyLong-term seizure outcomeLong-term seizure remissionPotential disease-modifying effectsPrimary long-term outcomeCommunity-based cohort studySignificant imaging abnormalitiesDisease-modifying effectsInitial treatment choiceLong-term outcomesInitial success rateGenetic absence modelSupporting Information sectionSeizure outcomeCohort studyFirst medicationSeizure remissionConvulsive seizuresImaging abnormalitiesInitial medication
2012
Age at onset of epilepsy, pharmacoresistance, and cognitive outcomes
Berg AT, Zelko FA, Levy SR, Testa FM. Age at onset of epilepsy, pharmacoresistance, and cognitive outcomes. Neurology 2012, 79: 1384-1391. PMID: 22972641, PMCID: PMC3448745, DOI: 10.1212/wnl.0b013e31826c1b55.Peer-Reviewed Original ResearchCitationsAltmetric
2011
Complete remission in nonsyndromic childhood‐onset epilepsy
Berg AT, Testa FM, Levy SR. Complete remission in nonsyndromic childhood‐onset epilepsy. Annals Of Neurology 2011, 70: 566-573. PMID: 21710620, PMCID: PMC3183287, DOI: 10.1002/ana.22461.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsComplete remissionNonsyndromic epilepsyProspective community-based cohortEarly seizure controlChildhood-onset epilepsyCommunity-based cohortProportional hazard modelingRisk of relapseKaplan-Meier approachSeizure outcomeSeizure controlSubsequent seizuresInitial diagnosisMultivariable analysisRemissionCohort membersEarly predictorBivariate analysisHazard modelingPoor chanceOlder ageRelapseEpilepsyCauseAge effects
2010
Parental report of behavioral and cognitive diagnoses in childhood-onset epilepsy: A case–sibling-controlled analysis
Benn EK, Hesdorffer DC, Levy SR, Testa FM, DiMario FJ, Berg AT. Parental report of behavioral and cognitive diagnoses in childhood-onset epilepsy: A case–sibling-controlled analysis. Epilepsy & Behavior 2010, 18: 276-279. PMID: 20494622, PMCID: PMC2902612, DOI: 10.1016/j.yebeh.2010.04.009.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsChildhood-onset epilepsyPsychiatric disordersSelf-injurious behaviorInfluence prognosisMetabolic insultsEpilepsySuicide attemptsCase childrenSibling controlsConnecticut StudyGenetic causeParent interviewsParental reportsDisordersLanguage disordersMorbidityPrognosisInsultDiagnosisControlYoung people
2009
Frequency, prognosis and surgical treatment of structural abnormalities seen with magnetic resonance imaging in childhood epilepsy
Berg AT, Mathern GW, Bronen RA, Fulbright RK, DiMario F, Testa FM, Levy SR. Frequency, prognosis and surgical treatment of structural abnormalities seen with magnetic resonance imaging in childhood epilepsy. Brain 2009, 132: 2785-2797. PMID: 19638447, PMCID: PMC2759335, DOI: 10.1093/brain/awp187.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsMeSH KeywordsAdolescentAge of OnsetAnticonvulsantsBrainChildChild, PreschoolCognitionCohort StudiesDrug ResistanceEpilepsyFemaleFunctional LateralityHumansImage Processing, Computer-AssistedInfantLogistic ModelsMagnetic Resonance ImagingMaleNeurologic ExaminationNeuropsychological TestsNeurosurgical ProceduresPrognosisSclerosisTomography, X-Ray ComputedConceptsMagnetic resonance imagingPositive MRI scansEpilepsy patientsMRI scansEpilepsy syndromesEpilepsy evaluationSurgical proceduresMultiple logistic regression analysisUse of MRIComprehensive epilepsy evaluationNon-idiopathic patientsPediatric epilepsy patientsComprehensive Epilepsy CenterPositive MRI findingsCommunity-based cohortNormal neurological examPre-surgical evaluationLogistic regression analysisIdiopathic epilepsy syndromesFrequency of lesionsClinical factorsMRI abnormalitiesMRI findingsNeurological examSurgical treatment
Academic Achievements & Community Involvement
honor Connecticut Magazine Top Docs 2016 through 2020
Regional AwardConnecticut MagazineDetails11/09/2020United Stateshonor July 2013 and 2014 Yale doctors make New York magazine’s best list
Regional AwardDetails11/09/2020United Stateshonor Connecticut Magazine Top Docs 2015 to 2020
Regional AwardConnecticut MagazineDetails04/03/2015United States
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