2021
Influence of Menthol and Green Apple E-Liquids Containing Different Nicotine Concentrations Among Youth E-Cigarette Users
Jackson A, Green B, Erythropel HC, Kong G, Cavallo DA, Eid T, Gueorguieva R, Buta E, O’Malley S, Krishnan-Sarin S. Influence of Menthol and Green Apple E-Liquids Containing Different Nicotine Concentrations Among Youth E-Cigarette Users. Experimental And Clinical Psychopharmacology 2021, 29: 355-365. PMID: 32297782, PMCID: PMC7572568, DOI: 10.1037/pha0000368.Peer-Reviewed Original Research
2020
Informing the development of adolescent e-cigarette cessation interventions: A qualitative study
Kong G, Bold KW, Cavallo DA, Davis DR, Jackson A, Krishnan-Sarin S. Informing the development of adolescent e-cigarette cessation interventions: A qualitative study. Addictive Behaviors 2020, 114: 106720. PMID: 33162230, PMCID: PMC7785614, DOI: 10.1016/j.addbeh.2020.106720.Peer-Reviewed Original ResearchConceptsNegative moodSocial influenceCessation interventionsLack of motivationQuit experienceCommon withdrawal symptomsSocial normsFocus groupsWithdrawal symptomsAdolescentsMoodFocus group guideSocial reasonsInterventionQualitative studyQuittingNegative health effectsGroup guideCold turkeyE-cigarettesCuesExperienceSchoolsE-cigarette devices used on school grounds
Jackson A, Kong G, Wu R, Morean ME, Davis DR, Camenga DR, Cavallo DA, Bold KW, Simon P, Krishnan-Sarin S. E-cigarette devices used on school grounds. Addictive Behaviors 2020, 110: 106516. PMID: 32622027, PMCID: PMC7415711, DOI: 10.1016/j.addbeh.2020.106516.Peer-Reviewed Original ResearchComputerized Cognitive Behavioral Therapy for Substance Use Disorders in a Specialized Primary Care Practice: A Randomized Feasibility Trial to Address the RT Component of SBIRT.
Tetrault JM, Holt SR, Cavallo DA, O'Connor PG, Gordon MA, Corvino JK, Nich C, Carroll KM. Computerized Cognitive Behavioral Therapy for Substance Use Disorders in a Specialized Primary Care Practice: A Randomized Feasibility Trial to Address the RT Component of SBIRT. Journal Of Addiction Medicine 2020, 14: e303-e309. PMID: 32371660, DOI: 10.1097/adm.0000000000000663.Peer-Reviewed Original ResearchConceptsSubstance use disordersComputerized cognitive behavioral therapySubstance useCognitive behavioral therapySelf-reported substance useUse disordersTechnology-based treatmentsPrimary care settingSubstance use outcomesIntegrated addictions treatmentTechnology-based interventionsBehavioral therapyPrimary care practicesOverall positive outcomeSUD interventionsBrief interventionUnhealthy alcohol useDays abstinentPositive outcomesUse outcomesCare settingsAlcohol useStandard careAddiction treatmentTreatment settings
2019
Nicotine Use Disorders in Adolescents
Cavallo DA, Krishnan-Sarin S. Nicotine Use Disorders in Adolescents. Pediatric Clinics Of North America 2019, 66: 1053-1062. PMID: 31679596, DOI: 10.1016/j.pcl.2019.08.002.Peer-Reviewed Original ResearchHigh school students’ use of flavored e-cigarette e-liquids for appetite control and weight loss
Morean ME, Bold KW, Kong G, Camenga D, Simon P, Jackson A, Cavallo DA, Krishnan-Sarin S. High school students’ use of flavored e-cigarette e-liquids for appetite control and weight loss. Addictive Behaviors 2019, 102: 106139. PMID: 31704428, PMCID: PMC6948184, DOI: 10.1016/j.addbeh.2019.106139.Peer-Reviewed Original ResearchConceptsE-liquid useAppetite controlWeight-related reasonsWeight lossE-liquidsAdolescent e-cigarette usersE-cigarette initiationE-cigarette usersSubset of adolescentsSchool-based surveyNicotine exposureFlavored e-liquidsSmoking frequencyInclusion criteriaAnalytic sampleVapingNaïve individualsFrequent vapingCurrent usersAdolescentsSchool adolescentsHigh school adolescentsNon-missing dataSmokingControlInfluence of combined treatment with naltrexone and memantine on alcohol drinking behaviors: a phase II randomized crossover trial
Krishnan-Sarin S, O’Malley S, Franco N, Cavallo DA, Tetrault JM, Shi J, Gueorguieva R, Pittman B, Krystal JH. Influence of combined treatment with naltrexone and memantine on alcohol drinking behaviors: a phase II randomized crossover trial. Neuropsychopharmacology 2019, 45: 319-326. PMID: 31590179, PMCID: PMC6901445, DOI: 10.1038/s41386-019-0536-z.Peer-Reviewed Original ResearchConceptsAlcohol drinking behaviorFirst treatment periodTreatment periodNumber of drinksCrossover trialDrinking behaviorEfficacy of naltrexoneOpioid antagonist naltrexoneNMDA antagonist memantinePositive family historyDay treatment periodSelf-administration periodAlcohol-induced stimulationAd lib accessMemantine treatmentAntagonist naltrexoneOpioid systemFamily historyNTXPriming drinkMemantineNaltrexoneAlcohol cravingHeavy drinkersAlcohol dependenceAdolescents’ awareness of the nicotine strength and e-cigarette status of JUUL e-cigarettes
Morean ME, Bold KW, Kong G, Gueorguieva R, Camenga DR, Simon P, Jackson A, Cavallo DA, Krishnan-Sarin S. Adolescents’ awareness of the nicotine strength and e-cigarette status of JUUL e-cigarettes. Drug And Alcohol Dependence 2019, 204: 107512. PMID: 31487572, PMCID: PMC6878179, DOI: 10.1016/j.drugalcdep.2019.05.032.Peer-Reviewed Original ResearchSystematic review of cigars, cigarillos, and little cigars among adolescents: Setting research agenda to inform tobacco control policy
Kong G, Creamer MR, Simon P, Cavallo DA, Ross JC, Hinds JT, Fishbein H, Gutierrez K. Systematic review of cigars, cigarillos, and little cigars among adolescents: Setting research agenda to inform tobacco control policy. Addictive Behaviors 2019, 96: 192-197. PMID: 31125939, PMCID: PMC6645397, DOI: 10.1016/j.addbeh.2019.04.032.Peer-Reviewed Original ResearchYouth generated prevention messages about electronic cigarettes
Cavallo DA, Kong G, Ells DM, Camenga DR, Morean ME, Krishnan-Sarin S. Youth generated prevention messages about electronic cigarettes. Health Education Research 2019, 34: 247-256. PMID: 30753438, PMCID: PMC6424147, DOI: 10.1093/her/cyz001.Peer-Reviewed Original ResearchConceptsE-cigarettesE-cigarette useLong-term health effectsSmoking statusE-cigarette preventionTobacco usePrevention messagesAge groupsElectronic cigarettesMessage themesHealth effectsHealth benefitsCigarettesHealth risksSocial disadvantageFocus groupsPowerful determinantParticipantsSmokersGroupMain themes
2018
E-cigarette devices used by high-school youth
Krishnan-Sarin S, Jackson A, Morean M, Kong G, Bold KW, Camenga DR, Cavallo DA, Simon P, Wu R. E-cigarette devices used by high-school youth. Drug And Alcohol Dependence 2018, 194: 395-400. PMID: 30497057, PMCID: PMC6312472, DOI: 10.1016/j.drugalcdep.2018.10.022.Peer-Reviewed Original ResearchQuerying About the Use of Specific E-Cigarette Devices May Enhance Accurate Measurement of E-Cigarette Prevalence Rates Among High School Students
Morean ME, Camenga DR, Bold KW, Kong G, Jackson A, Simon P, Cavallo DA, Krishnan-Sarin S. Querying About the Use of Specific E-Cigarette Devices May Enhance Accurate Measurement of E-Cigarette Prevalence Rates Among High School Students. Nicotine & Tobacco Research 2018, 22: 833-837. PMID: 30395344, PMCID: PMC7171282, DOI: 10.1093/ntr/nty240.Peer-Reviewed Original ResearchPET imaging reveals lower kappa opioid receptor availability in alcoholics but no effect of age
Vijay A, Cavallo D, Goldberg A, de Laat B, Nabulsi N, Huang Y, Krishnan-Sarin S, Morris ED. PET imaging reveals lower kappa opioid receptor availability in alcoholics but no effect of age. Neuropsychopharmacology 2018, 43: 2539-2547. PMID: 30188515, PMCID: PMC6224533, DOI: 10.1038/s41386-018-0199-1.Peer-Reviewed Original ResearchConceptsHealthy control cohortVolume of distributionOpioid receptor systemKappa-opioid receptorsOpioid receptorsDelta opioid receptor systemReceptor systemMu-opioid receptor systemOpioid receptor availabilityPotential pharmacological targetEffect of ageAge-related declineControl cohortPET scansAntagonist tracersReceptor availabilityMultivariate analysisPharmacological targetsPET imagingReceptorsAgePartial volume correctionCohortVT valuesPresent studySocioeconomic status and adolescent e-cigarette use: The mediating role of e-cigarette advertisement exposure
Simon P, Camenga D, Morean M, Kong G, Bold KW, Cavallo DA, Krishnan-Sarin S. Socioeconomic status and adolescent e-cigarette use: The mediating role of e-cigarette advertisement exposure. Preventive Medicine 2018, 112: 193-198. PMID: 29673887, PMCID: PMC6007030, DOI: 10.1016/j.ypmed.2018.04.019.Peer-Reviewed Original ResearchConceptsE-cigarette useE-cigarette advertisementsSocioeconomic statusAdolescent e-cigarette useE-cigarette advertising exposureAdvertising exposureLow socioeconomic statusE-cigarette advertisingTobacco product useDifferent SES groupsHigher socioeconomic statusRace/ethnicityE-cigarette advertisement exposureCigarette useS groupPast month frequencyAnonymous surveyCigarette advertisingProduct useAdvertisement exposureYouth exposureGreater frequencyExposureAssociationGreater exposureAddressing discordant quantitative urine buprenorphine and norbuprenorphine levels: Case examples in opioid use disorder
Holt SR, Donroe JH, Cavallo DA, Tetrault JM. Addressing discordant quantitative urine buprenorphine and norbuprenorphine levels: Case examples in opioid use disorder. Drug And Alcohol Dependence 2018, 186: 171-174. PMID: 29579725, DOI: 10.1016/j.drugalcdep.2017.12.040.Peer-Reviewed Original ResearchConceptsOngoing illicit drug usePatient-provider relationshipOpioid use disorderIllicit drug useUse disordersUrine adulterationTreatment planDrug useQuantitative urine testingMethadone treatment programsSubstance use disordersNorbuprenorphine levelsUrine buprenorphineUrine testingPatientsTreatment programNonjudgmental approachUrine samplesTherapeutic allianceDiscordant levelsBuprenorphineDisordersUrineNorbuprenorphineLevelsE-cigarette advertising exposure in e-cigarette naïve adolescents and subsequent e-cigarette use: A longitudinal cohort study
Camenga D, Gutierrez KM, Kong G, Cavallo D, Simon P, Krishnan-Sarin S. E-cigarette advertising exposure in e-cigarette naïve adolescents and subsequent e-cigarette use: A longitudinal cohort study. Addictive Behaviors 2018, 81: 78-83. PMID: 29432916, PMCID: PMC5845830, DOI: 10.1016/j.addbeh.2018.02.008.Peer-Reviewed Original ResearchConceptsSubsequent e-cigarette useE-cigarette useE-cigarette advertisingE-cigarettesLogistic regressionE-cigarette advertising exposureWave 2Wave 1School-based cohortCigarette smoking statusLongitudinal cohort studyMultivariate logistic regressionPopular tobacco productAdvertising exposureTobacco use behaviorsCohort studySmoking statusCigarette smokingLongitudinal cohortWhite raceElectronic cigarettesTobacco productsNaïve adolescentsCohortExposurePreferring more e-cigarette flavors is associated with e-cigarette use frequency among adolescents but not adults
Morean ME, Butler ER, Bold KW, Kong G, Camenga DR, Cavallo DA, Simon P, O’Malley S, Krishnan-Sarin S. Preferring more e-cigarette flavors is associated with e-cigarette use frequency among adolescents but not adults. PLOS ONE 2018, 13: e0189015. PMID: 29300749, PMCID: PMC5754053, DOI: 10.1371/journal.pone.0189015.Peer-Reviewed Original ResearchConceptsE-cigarette useE-cigarette usersPast-month e-cigarette usersE-cigarette use frequencyE-cigarette flavorsE-liquidsMore daysFrequent e-cigarette useSchool-based surveyTotal numberFlavor preferencesAdult e-cigarette usersAdolescent e-cigarette useE-cigarettesUse frequencyAnalytic sampleAdultsSample of adolescentsAdolescentsGreater total numberLiquid flavorsConnecticut high schoolsAdult samplesLarge proportionDaysTrajectories of E-Cigarette and Conventional Cigarette Use Among Youth
Bold KW, Kong G, Camenga DR, Simon P, Cavallo DA, Morean ME, Krishnan-Sarin S. Trajectories of E-Cigarette and Conventional Cigarette Use Among Youth. Pediatrics 2018, 141: e20171832. PMID: 29203523, PMCID: PMC5744268, DOI: 10.1542/peds.2017-1832.Peer-Reviewed Original Research
2017
Early age of e-cigarette use onset mediates the association between impulsivity and e-cigarette use frequency in youth
Bold KW, Morean ME, Kong G, Simon P, Camenga DR, Cavallo DA, Krishnan-Sarin S. Early age of e-cigarette use onset mediates the association between impulsivity and e-cigarette use frequency in youth. Drug And Alcohol Dependence 2017, 181: 146-151. PMID: 29055268, PMCID: PMC5683935, DOI: 10.1016/j.drugalcdep.2017.09.025.Peer-Reviewed Original ResearchConceptsE-cigarette useMore frequent e-cigarette useEarly ageFrequent e-cigarette useE-cigarette use onsetLong-term useE-cigarette initiationE-cigarette usersE-cigarette use frequencyE-cigarette interventionsBehavioral impulsivityRisk factorsEarly initiationUnknown health effectsDomains of impulsivityImpulsive youthE-cigarettesGreater riskPast monthStudying the interactive effects of menthol and nicotine among youth: An examination using e-cigarettes
Krishnan-Sarin S, Green BG, Kong G, Cavallo DA, Jatlow P, Gueorguieva R, Buta E, O’Malley S. Studying the interactive effects of menthol and nicotine among youth: An examination using e-cigarettes. Drug And Alcohol Dependence 2017, 180: 193-199. PMID: 28915478, PMCID: PMC5659733, DOI: 10.1016/j.drugalcdep.2017.07.044.Peer-Reviewed Original ResearchConceptsAd lib useE-cigarettesE-cigarette usersStimulant effectsNicotine concentrationsNicotine-containing e-cigarettesNicotine withdrawal symptomsMenthol concentrationRandom counterbalanced orderPositive rewarding effectsNicotine exposureNicotine withdrawalWithdrawal symptomsRewarding effectsMenthol glucuronideHigh menthol concentrationLow dosesNicotine levelsTobacco productsNicotineCounterbalanced order