1996
Detection of rare circulating human colon tumor cells in a nude mouse xenograft model
Pages J, Sordat B, Bautista D, Costa J, Benhattar J. Detection of rare circulating human colon tumor cells in a nude mouse xenograft model. Cancer Letters 1996, 106: 139-144. PMID: 8827058, DOI: 10.1016/0304-3835(96)04319-4.Peer-Reviewed Original ResearchConceptsHuman colon tumor cellsTumor cellsColon tumor cellsSensitive allele-specific polymerase chain reactionExperimental modelNude mouse xenograft modelK-ras mutationsMouse xenograft modelAllele-specific polymerase chain reactionK-ras geneLymph nodesPrimary implantationSpecific polymerase chain reactionHuman colon carcinoma cellsMicrometastatic depositsPolymerase chain reactionColon carcinoma cellsXenograft modelNude miceGAT mutationMetastatic processCarcinoma cellsBloodChain reactionOccurrence of cells
1993
Prognostic significance of K-ras mutations in colorectal carcinoma
Benhattar J, Losi L, Chaubert P, Givel J, Costa J. Prognostic significance of K-ras mutations in colorectal carcinoma. Gastroenterology 1993, 104: 1044-1048. PMID: 8462792, DOI: 10.1016/0016-5085(93)90272-e.Peer-Reviewed Original ResearchConceptsK-ras mutationsPrognostic significanceColorectal carcinomaK-ras geneRecurrent diseaseCodon 12Good prognostic factorAdvanced colorectal carcinomaPossible prognostic significanceHuman colorectal carcinomaPolymerase chain reaction-based techniquesDukes' BPrognostic factorsColorectal cancerPrimary tumorOverall prevalenceHigh riskPatientsRas mutationsCarcinomaHuman tumorsTumorsDiseasePrevalenceGGT
1986
High‐grade soft tissue sarcomas of the extremities
Potter D, Kinsella T, Glatstein E, Wesley R, White D, Seipp C, Chang A, Lack E, Costa J, Rosenberg S. High‐grade soft tissue sarcomas of the extremities. Cancer 1986, 58: 190-205. PMID: 3518911, DOI: 10.1002/1097-0142(19860701)58:1<190::aid-cncr2820580133>3.0.co;2-5.Peer-Reviewed Original ResearchMeSH KeywordsActuarial AnalysisAdolescentAdultAgedAmputation, SurgicalAntineoplastic Combined Chemotherapy ProtocolsArmChildClinical Trials as TopicCombined Modality TherapyFemaleFollow-Up StudiesHumansLegMaleMiddle AgedNeoplasm MetastasisNeoplasm Recurrence, LocalPrognosisRandom AllocationSarcomaThighConceptsHigh-grade soft tissue sarcomasSoft tissue sarcomasNational Cancer InstituteLimb-sparing proceduresSignificant prognostic variablesOverall survivalAdjuvant chemotherapyTissue sarcomasPrognostic variablesDecreased overall survivalOutcomes of patientsDisease-free survivalMicroscopic marginsPostoperative radiotherapyFirst recurrenceProspective trialRecurrent diseaseSurgery BranchHistologic typeLocal excisionRandomized trialsPatient refusalTumor sizeCancer InstitutePatients
1983
“Low grade” mucoepidermoid carcinoma of the bronchus with “high grade” biological behavior
Barsky S, Martin S, Matthews M, Gazdar A, Costa J. “Low grade” mucoepidermoid carcinoma of the bronchus with “high grade” biological behavior. Cancer 1983, 51: 1505-1509. PMID: 6825057, DOI: 10.1002/1097-0142(19830415)51:8<1505::aid-cncr2820510825>3.0.co;2-9.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnimalsBronchial NeoplasmsCarcinomaFemaleHumansMiceMice, NudeNeoplasm MetastasisNeoplasm TransplantationConceptsLow-grade histologic featuresMucoepidermoid carcinomaWidespread metastasesHistologic featuresBiological behaviorLow-grade mucoepidermoid carcinomaPrimary endobronchial tumorsHigh-grade lesionsLow-grade lesionsAggressive biological behaviorGrade mucoepidermoid carcinomaNumerous goblet cellsLow gradeGlycogen-rich cellsEndobronchial massEndobronchial tumorPrimary tumorMonomorphic cellsOriginal tumorMorphologic patternsNude miceGoblet cellsCarcinomaSubcutaneous tissueMetastasis
1982
Unusual Intranuclear Inclusions in Malignant Fibrous Histiocytoma: Presence in Primary Tumor
Tralka T, Yee C, Triche T, Costa J, Dienes H. Unusual Intranuclear Inclusions in Malignant Fibrous Histiocytoma: Presence in Primary Tumor. Ultrastructural Pathology 1982, 3: 161-167. PMID: 6285572, DOI: 10.3109/01913128209016640.Peer-Reviewed Original Research
1978
Osteosarcoma associated with thorotrast administration. Report of two cases and literature review
Sindelar W, Costa J, Ketcham A. Osteosarcoma associated with thorotrast administration. Report of two cases and literature review. Cancer 1978, 42: 2604-2609. PMID: 365315, DOI: 10.1002/1097-0142(197812)42:6<2604::aid-cncr2820420615>3.0.co;2-o.Peer-Reviewed Original ResearchConceptsCases of osteosarcomaPathologic evidencePrimary tumorThorotrast depositsPossible causal relationshipReticuloendothelial systemOsteosarcomaPrevious casesChronic radiationPatientsNeoplastic transformationAdministrationBoneLiterature reviewAngiographyCausal relationshipHistologyTumorsThorotrastCases