Publications

2024

• Lipid mediators in neutrophil biology: inflammation, resolution and beyond.Ghodsi A, Hidalgo A, Libreros S. Lipid mediators in neutrophil biology: inflammation, resolution and beyond. Curr Opin Hematol 2024, 31: 175-192. PMID: 38727155, DOI: 10.1097/MOH.0000000000000822.
• A dual-acting DNASE1/DNASE1L3 biologic prevents autoimmunity and death in genetic and induced lupus models.Stabach PR, Sims D, Gomez-Bañuelos E, Zehentmeier S, Dammen-Brower K, Bernhisel A, Kujawski SE, Lopez SG, Petri M, Goldman DW, Lester ER, Le Q, Ishaq T, Kim H, Srivastava S, Kumar D, Pereira JP, Yarema KJ, Koumpouras F, Andrade F, Braddock DT. A dual-acting DNASE1/DNASE1L3 biologic prevents autoimmunity and death in genetic and induced lupus models. JCI Insight 2024 PMID: 38888971, DOI: 10.1172/jci.insight.177003.
• Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinomaEl Zarif T, Semaan K, Eid M, Seo J, Garinet S, Davidsohn M, Sahgal P, Fortunato B, Canniff J, Nassar A, Abou Alaiwi S, Bakouny Z, Lakshminarayanan G, Savignano H, Lyons K, Matar S, Ali A, Saad E, Saliby R, Cordeiro P, Zhang Z, El Ahmar N, Laimon Y, Labaki C, Shah V, Freeman D, O'Toole J, Lee G, Hwang J, Pomerantz M, Signoretti S, Van Allen E, Xie W, Berchuck J, Viswanathan S, Braun D, Choueiri T, Freedman M, Baca S. Epigenomic signatures of sarcomatoid differentiation to guide the treatment of renal cell carcinoma. Cell Reports 2024, 43: 114350. PMID: 38870013, DOI: 10.1016/j.celrep.2024.114350.
• High-throughput transcriptome profiling indicates ribosomal RNAs to be associated with resistance to immunotherapy in non-small cell lung cancer (NSCLC)Moutafi M, Bates K, Aung T, Milian R, Xirou V, Vathiotis I, Gavrielatou N, Angelakis A, Schalper K, Salichos L, Rimm D. High-throughput transcriptome profiling indicates ribosomal RNAs to be associated with resistance to immunotherapy in non-small cell lung cancer (NSCLC). Journal For ImmunoTherapy Of Cancer 2024, 12: e009039. PMID: 38857914, PMCID: PMC11168162, DOI: 10.1136/jitc-2024-009039.
• Spatially informed gene signatures for response to immunotherapy in melanoma.Aung T, Warrell J, Martinez-Morilla S, Gavrielatou N, Vathiotis I, Yaghoobi V, Kluger H, Gerstein M, Rimm D. Spatially informed gene signatures for response to immunotherapy in melanoma. Clinical Cancer Research 2024 PMID: 38837895, DOI: 10.1158/1078-0432.ccr-23-3932.
• Clinicopathologic Characteristics of MYC Copy Number Amplification in Breast Cancer.Sun T, Golestani R, Zhan H, Krishnamurti U, Harigopal M, Zhong M, Liang Y. Clinicopathologic Characteristics of MYC Copy Number Amplification in Breast Cancer. International Journal Of Surgical Pathology 2024, 10668969241256109. PMID: 38839260, DOI: 10.1177/10668969241256109.
• Fibroepithelial Neoplasm with Hybrid Features of Benign Phyllodes Tumor, Juvenile Papillomatosis, and Juvenile Fibroadenoma: A Case Report.Liu B, Mehrotra M, Kowtha L, Guan M, Houldsworth J, Baskovich B, Harigopal M. Fibroepithelial Neoplasm with Hybrid Features of Benign Phyllodes Tumor, Juvenile Papillomatosis, and Juvenile Fibroadenoma: A Case Report. International Journal Of Surgical Pathology 2024, 10668969241256112. PMID: 38839253, DOI: 10.1177/10668969241256112.
• SACI-IO HR+: A randomized phase II trial of sacituzumab govitecan with or without pembrolizumab in patients with metastatic hormone receptor-positive/HER2-negative breast cancer.Garrido-Castro A, Kim S, Desrosiers J, Nanda R, Carey L, Clark A, Sacks R, O'Connor T, Sinclair N, Lo K, Thomas A, Wrabel E, O'Meara T, Lin N, Burstein H, He M, Rimm D, Mittendorf E, Tayob N, Tolaney S. SACI-IO HR+: A randomized phase II trial of sacituzumab govitecan with or without pembrolizumab in patients with metastatic hormone receptor-positive/HER2-negative breast cancer. Journal Of Clinical Oncology 2024, 42: lba1004-lba1004. DOI: 10.1200/jco.2024.42.17_suppl.lba1004.
• Psychosocial burden of autoimmune blistering diseases: A comprehensive survey studyWhite M, Hoffman V, Yale M, Strong R, Tomayko M. Psychosocial burden of autoimmune blistering diseases: A comprehensive survey study. Journal Of The European Academy Of Dermatology And Venereology 2024 PMID: 38837452, DOI: 10.1111/jdv.20156.
• Granuloma Annulare Exhibits Mixed Immune and Macrophage Polarization Profiles with Spatial TranscriptomicsMohanty C, Singh C, Daccache J, Damsky W, Kendziorski C, Yan D, Prasad A, Zhang D, Keenan T, Drolet B, Ahmad N, Shields B. Granuloma Annulare Exhibits Mixed Immune and Macrophage Polarization Profiles with Spatial Transcriptomics. Journal Of Investigative Dermatology 2024 PMID: 38844128, DOI: 10.1016/j.jid.2024.04.024.
• A Small Molecule Allele-selective Transcriptional Inhibitor of the MIF Immune Susceptibility LocusLi J, Leng L, Pantouris G, Manjula R, Piecychna M, Abriola L, Hu B, Lolis E, Armstrong M, Donnelly S, Bucala R. A Small Molecule Allele-selective Transcriptional Inhibitor of the MIF Immune Susceptibility Locus. Journal Of Biological Chemistry 2024, 107443. PMID: 38838773, DOI: 10.1016/j.jbc.2024.107443.
• SenNet recommendations for detecting senescent cells in different tissuesSuryadevara V, Hudgins A, Rajesh A, Pappalardo A, Karpova A, Dey A, Hertzel A, Agudelo A, Rocha A, Soygur B, Schilling B, Carver C, Aguayo-Mazzucato C, Baker D, Bernlohr D, Jurk D, Mangarova D, Quardokus E, Enninga E, Schmidt E, Chen F, Duncan F, Cambuli F, Kaur G, Kuchel G, Lee G, Daldrup-Link H, Martini H, Phatnani H, Al-Naggar I, Rahman I, Nie J, Passos J, Silverstein J, Campisi J, Wang J, Iwasaki K, Barbosa K, Metis K, Nernekli K, Niedernhofer L, Ding L, Wang L, Adams L, Ruiyang L, Doolittle M, Teneche M, Schafer M, Xu M, Hajipour M, Boroumand M, Basisty N, Sloan N, Slavov N, Kuksenko O, Robson P, Gomez P, Vasilikos P, Adams P, Carapeto P, Zhu Q, Ramasamy R, Perez-Lorenzo R, Fan R, Dong R, Montgomery R, Shaikh S, Vickovic S, Yin S, Kang S, Suvakov S, Khosla S, Garovic V, Menon V, Xu Y, Song Y, Suh Y, Dou Z, Neretti N. SenNet recommendations for detecting senescent cells in different tissues. Nature Reviews Molecular Cell Biology 2024, 1-23. PMID: 38831121, DOI: 10.1038/s41580-024-00738-8.
• Dormant origin firing promotes head-on transcription-replication conflicts at transcription termination sites in response to BRCA2 deficiencyGoehring L, Keegan S, Lahiri S, Xia W, Kong M, Jimenez-Sainz J, Gupta D, Drapkin R, Jensen R, Smith D, Rothenberg E, Fenyö D, Huang T. Dormant origin firing promotes head-on transcription-replication conflicts at transcription termination sites in response to BRCA2 deficiency. Nature Communications 2024, 15: 4716. PMID: 38830843, PMCID: PMC11148086, DOI: 10.1038/s41467-024-48286-1.
• Chest computed tomography provides more information than chest X-ray alone in determining extent of physiologic impairment in pulmonary sarcoidosisBenn B, Lippitt W, Cortopassi I, G.K B, Barbosa E, Drake W, Herzog E, Gibson K, Chen E, Koth L, Fuhrman C, Lynch D, Kaminski N, Wisniewski S, Carlson N, Maier L. Chest computed tomography provides more information than chest X-ray alone in determining extent of physiologic impairment in pulmonary sarcoidosis. CHEST Journal 2024 PMID: 38830401, DOI: 10.1016/j.chest.2024.04.031.
• Spatially resolved tissue imaging to analyze the tumor immune microenvironment: beyond cell-type densitiesJaneiro A, Wong E, Jiménez-Sánchez D, de Solorzano C, Lozano M, Teijeira A, Schalper K, Melero I, De Andrea C. Spatially resolved tissue imaging to analyze the tumor immune microenvironment: beyond cell-type densities. Journal For ImmunoTherapy Of Cancer 2024, 12: e008589. PMID: 38821717, PMCID: PMC11149121, DOI: 10.1136/jitc-2023-008589.
• Mechanism of Action of KL-50, a Candidate Imidazotetrazine for the Treatment of Drug-Resistant Brain CancersHuseman E, Lo A, Fedorova O, Elia J, Gueble S, Lin K, Sundaram R, Oh J, Liu J, Menges F, Rees M, Ronan M, Roth J, Batista V, Crawford J, Pyle A, Bindra R, Herzon S. Mechanism of Action of KL-50, a Candidate Imidazotetrazine for the Treatment of Drug-Resistant Brain Cancers. Journal Of The American Chemical Society 2024 PMID: 38815248, DOI: 10.1021/jacs.3c06483.
• Single-Cell Transcriptomic Analyses of Brain Parenchyma in Patients With New-Onset Refractory Status Epilepticus (NORSE)Hanin A, Zhang L, Huttner A, Plu I, Mathon B, Bielle F, Navarro V, Hirsch L, Hafler D. Single-Cell Transcriptomic Analyses of Brain Parenchyma in Patients With New-Onset Refractory Status Epilepticus (NORSE). Neurology Neuroimmunology & Neuroinflammation 2024, 11: e200259. PMID: 38810181, PMCID: PMC11139018, DOI: 10.1212/nxi.0000000000200259.
• Virtual Remote Pathology Education in Support of Virtual Remote Gynecologic-Oncology Training: The Open Pathology Education Network Pilot Proof of Concept Experience.Hassell L, Wong A, Parkash V, Ng J, Tran N, Huynh L, Truong N, Tran T, Phan T, Tran T. Virtual Remote Pathology Education in Support of Virtual Remote Gynecologic-Oncology Training: The Open Pathology Education Network Pilot Proof of Concept Experience. Archives Of Pathology & Laboratory Medicine 2024 PMID: 38802102, DOI: 10.5858/arpa.2023-0449-ep.
• Endometriosis in a 22-Year-Old with Premature Ovarian Insufficiency Secondary to Pre-Pubertal Bone Marrow Transplant: a Case ReportLiao C, Ramani S, Parkash V, Kodaman P. Endometriosis in a 22-Year-Old with Premature Ovarian Insufficiency Secondary to Pre-Pubertal Bone Marrow Transplant: a Case Report. Reproductive Sciences 2024, 1-6. PMID: 38806998, DOI: 10.1007/s43032-024-01601-z.
• Fetal Brain-Derived Exosomal miRNAs from Maternal Blood: Potential Diagnostic Biomarkers for Fetal Alcohol Spectrum Disorders (FASDs)Darbinian N, Hampe M, Martirosyan D, Bajwa A, Darbinyan A, Merabova N, Tatevosian G, Goetzl L, Amini S, Selzer M. Fetal Brain-Derived Exosomal miRNAs from Maternal Blood: Potential Diagnostic Biomarkers for Fetal Alcohol Spectrum Disorders (FASDs). International Journal Of Molecular Sciences 2024, 25: 5826. PMCID: PMC11172088, DOI: 10.3390/ijms25115826.
• Quantitative correlation of ENPP1 pathogenic variants with disease phenotypeAnsh A, Stabach P, Ciccone C, Cao W, De La Cruz E, Sabbagh Y, Carpenter T, Ferreira C, Braddock D. Quantitative correlation of ENPP1 pathogenic variants with disease phenotype. Bone 2024, 186: 117136. PMID: 38806089, DOI: 10.1016/j.bone.2024.117136.
• Macrophage-derived macrophage migration inhibitory factor mediates renal injury in anti-glomerular basement membrane glomerulonephritisYang H, Li J, Huang X, Bucala R, Xu A, Lan H. Macrophage-derived macrophage migration inhibitory factor mediates renal injury in anti-glomerular basement membrane glomerulonephritis. Frontiers In Immunology 2024, 15: 1361343. PMID: 38846956, PMCID: PMC11153660, DOI: 10.3389/fimmu.2024.1361343.
• The Evolution of Mouse Models of Cancer: Past, Present, and Future.Abate-Shen C, Politi K. The Evolution of Mouse Models of Cancer: Past, Present, and Future. Cold Spring Harbor Perspectives In Medicine 2024, a041736. PMID: 38772706, DOI: 10.1101/cshperspect.a041736.
• Neoadjuvant Cisplatin, Gemcitabine, and Docetaxel in Sarcomatoid Bladder Cancer – Clinical Activity and Whole Transcriptome AnalysisJohnson III B, Teply B, Kagemann C, McGuire B, Lombardo K, Jing Y, Langbo W, Epstein J, Netto G, Baras A, Matoso A, McConkey D, Gupta A, Ahuja N, Ross A, Pierorazio P, Comperat E, Hoffman-Censits J, Singla N, Patel S, Kates M, Choi W, Bivalacqua T, Hahn N. Neoadjuvant Cisplatin, Gemcitabine, and Docetaxel in Sarcomatoid Bladder Cancer – Clinical Activity and Whole Transcriptome Analysis. Bladder Cancer 2024, 1-11. DOI: 10.3233/blc-240008.
• Enhancing in vivo cell and tissue targeting by modulation of polymer nanoparticles and macrophage decoysPiotrowski-Daspit A, Bracaglia L, Eaton D, Richfield O, Binns T, Albert C, Gould J, Mortlock R, Egan M, Pober J, Saltzman W. Enhancing in vivo cell and tissue targeting by modulation of polymer nanoparticles and macrophage decoys. Nature Communications 2024, 15: 4247. PMID: 38762483, PMCID: PMC11102454, DOI: 10.1038/s41467-024-48442-7.
• De Novo Elastin Assembly Alleviates Development of Supravalvular Aortic Stenosis.Ellis M, Riaz M, Huang Y, Anderson C, Hoareau M, Li X, Luo H, Lee S, Park J, Luo J, Batty L, Huang Q, Lopez C, Reinhardt D, Tellides G, Qyang Y. De Novo Elastin Assembly Alleviates Development of Supravalvular Aortic Stenosis. Arteriosclerosis Thrombosis And Vascular Biology 2024 PMID: 38752350, DOI: 10.1161/atvbaha.124.320790.
• The development of hair follicles and nailLee S, Platt S, Lim C, Ito M, Myung P. The development of hair follicles and nail. Developmental Biology 2024, 513: 3-11. PMID: 38759942, DOI: 10.1016/j.ydbio.2024.05.010.
• Reliable detection of stochastic epigenetic mutations and associations with cardiovascular agingMarkov Y, Levine M, Higgins-Chen A. Reliable detection of stochastic epigenetic mutations and associations with cardiovascular aging. GeroScience 2024, 1-21. PMID: 38736015, DOI: 10.1007/s11357-024-01191-3.
• Sarcomatoid and Rhabdoid Renal Cell Carcinoma: Clinical, Pathologic, and Molecular Genetic Features.Adeniran A, Shuch B, Humphrey P. Sarcomatoid and Rhabdoid Renal Cell Carcinoma: Clinical, Pathologic, and Molecular Genetic Features. The American Journal Of Surgical Pathology 2024 PMID: 38736105, DOI: 10.1097/pas.0000000000002233.
• von Meyenburg complexes are more frequently associated with cholangiocarcinomaJain D, Khandakar B, Ni P, Kenney B, Qin L, Deshpande V, Fiel M. von Meyenburg complexes are more frequently associated with cholangiocarcinoma. Journal Of Clinical Pathology 2024, jcp-2024-209572. PMID: 38729770, DOI: 10.1136/jcp-2024-209572.
• Single-Cell Profiling Reveals Immune Aberrations in Progressive Idiopathic Pulmonary Fibrosis.Unterman A, Zhao A, Neumark N, Schupp J, Ahangari F, Cosme C, Sharma P, Flint J, Stein Y, Ryu C, Ishikawa G, Sumida T, Gomez J, Herazo-Maya J, Dela Cruz C, Herzog E, Kaminski N. Single-Cell Profiling Reveals Immune Aberrations in Progressive Idiopathic Pulmonary Fibrosis. American Journal Of Respiratory And Critical Care Medicine 2024 PMID: 38717443, DOI: 10.1164/rccm.202306-0979oc.
• Artificial intelligence–aided steatosis assessment in donor livers according to the Banff consensus recommendationsJiao J, Tang H, Sun N, Zhang X. Artificial intelligence–aided steatosis assessment in donor livers according to the Banff consensus recommendations. American Journal Of Clinical Pathology 2024, aqae053. PMID: 38716796, DOI: 10.1093/ajcp/aqae053.
• Reply to Dow and SmithMamoun C, Wormser G. Reply to Dow and Smith. The Journal Of Infectious Diseases 2024, jiae194. PMID: 38712965, DOI: 10.1093/infdis/jiae194.
• Adenocarcinoma of anogenital mammary gland type arising from encapsulated papillary carcinoma: A rare vulvar tumor mimicking breast carcinomaTang H, Laskin W, Luan Y, McNiff J, Zhan H. Adenocarcinoma of anogenital mammary gland type arising from encapsulated papillary carcinoma: A rare vulvar tumor mimicking breast carcinoma. Journal Of Cutaneous Pathology 2024 PMID: 38711196, DOI: 10.1111/cup.14639.
• Adiposity, immunity, and inflammation: interrelationships in health and disease: A report from 24th annual Harvard nutrition obesity symposium, June 2023Burak M, Stanley T, Lawson E, Campbell S, Lynch L, Hasty A, Domingos A, Dixit V, Hotamışlıgil G, Sheedy F, Dixon A, Brinkley T, Hill J, Donath M, Grinspoon S. Adiposity, immunity, and inflammation: interrelationships in health and disease: A report from 24th annual Harvard nutrition obesity symposium, June 2023. American Journal Of Clinical Nutrition 2024 PMID: 38705359, DOI: 10.1016/j.ajcnut.2024.04.029.
• Abstract PO3-13-11: Quantitative Multiplex Immunofluorescence Assay for TROP2 and HER2 Expression in Breast Cancer: Towards Guiding Patient Selection for Antibody Drug Conjugate TherapiesRobbins C, He M, Khaimova R, Bates K, Chan N, Liebler D, Fulton R, Rimm D. Abstract PO3-13-11: Quantitative Multiplex Immunofluorescence Assay for TROP2 and HER2 Expression in Breast Cancer: Towards Guiding Patient Selection for Antibody Drug Conjugate Therapies. Cancer Research 2024, 84: po3-13-11-po3-13-11. DOI: 10.1158/1538-7445.sabcs23-po3-13-11.
• Abstract PO4-15-03: Quantitative Measurement of TROP2 via Chromogenic Immunohistochemistry in Breast CancerHe M, Liu M, Aung T, Burela S, Bates K, Robbins C, Rimm D. Abstract PO4-15-03: Quantitative Measurement of TROP2 via Chromogenic Immunohistochemistry in Breast Cancer. Cancer Research 2024, 84: po4-15-03-po4-15-03. DOI: 10.1158/1538-7445.sabcs23-po4-15-03.
• Abstract PO5-13-11: Quantitative Assessment of HER2 Expression in Intraductal Neoplasms of the BreastChan N, Zhan H, Khaimova R, Aung T, Robbins C, Gaule P, Rimm D. Abstract PO5-13-11: Quantitative Assessment of HER2 Expression in Intraductal Neoplasms of the Breast. Cancer Research 2024, 84: po5-13-11-po5-13-11. DOI: 10.1158/1538-7445.sabcs23-po5-13-11.
• Exploiting Metabolic Defects in Glioma with Nanoparticle Encapsulated NAMPT Inhibitors.Murray M, Noronha K, Wang Y, Friedman A, Paradkar S, Suh H, Sundaram R, Brenner C, Saltzman W, Bindra R. Exploiting Metabolic Defects in Glioma with Nanoparticle Encapsulated NAMPT Inhibitors. Molecular Cancer Therapeutics 2024, of1-of12. PMID: 38691846, DOI: 10.1158/1535-7163.mct-24-0012.
• Intravenous immunoglobulin-induced eczematous dermatitis treated with dupilumabSingh K, Breidbart R, Jaiswal A, Damsky W, Choate K, Vesely M. Intravenous immunoglobulin-induced eczematous dermatitis treated with dupilumab. JAAD Case Reports 2024, 49: 102-105. DOI: 10.1016/j.jdcr.2024.05.002.
• Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortalityGygi J, Maguire C, Patel R, Shinde P, Konstorum A, Shannon C, Xu L, Hoch A, Jayavelu N, Haddad E, Network I, Reed E, Kraft M, McComsey G, Metcalf J, Ozonoff A, Esserman D, Cairns C, Rouphael N, Bosinger S, Kim-Schulze S, Krammer F, Rosen L, van Bakel H, Wilson M, Eckalbar W, Maecker H, Langelier C, Steen H, Altman M, Montgomery R, Levy O, Melamed E, Pulendran B, Diray-Arce J, Smolen K, Fragiadakis G, Becker P, Sekaly R, Ehrlich L, Fourati S, Peters B, Kleinstein S, Guan L. Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality. Journal Of Clinical Investigation 2024, 134: e176640. PMID: 38690733, PMCID: PMC11060740, DOI: 10.1172/jci176640.
• Alveolar Type 2 Cells With Impaired Proteostasis Signal to Monocyte-derived Macrophages Via a MIF/DDT-CD74 Signaling Network to Promotes Pulmonary Fibrosis in IPFKim S, Nouws J, Cooley J, Ahangari F, Leng L, Elias J, Kaminski N, Lee P, Redente E, Kang M, Sun H, Herzog E, Bucala R, Prasse A, Sauler M. Alveolar Type 2 Cells With Impaired Proteostasis Signal to Monocyte-derived Macrophages Via a MIF/DDT-CD74 Signaling Network to Promotes Pulmonary Fibrosis in IPF. 2024, a3001-a3001. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a3001.
• Role of Noradrenaline and Macrophage Dynamics in Pulmonary FibrosisIshikawa G, Peng X, Mcgovern J, Ghincea A, Saber T, Sun H, Sauler M, Ryu C, Herzog E. Role of Noradrenaline and Macrophage Dynamics in Pulmonary Fibrosis. 2024, a5206-a5206. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a5206.
• Innate Immune Effects of Α1-adrenoreceptor Antagonism in SarcoidosisSaber T, Yu S, Lee C, Fiorini V, Mcgovern J, Woo S, Gulati M, Ryu C, Herzog E. Innate Immune Effects of Α1-adrenoreceptor Antagonism in Sarcoidosis. 2024, a2531-a2531. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a2531.
• Telomere Attrition Is Associated With SarcoidosisGandhi S, Lee C, Yu S, Saber T, Woo S, Mcgovern J, Fiorini V, Gulati M, Herzog E, Ryu C. Telomere Attrition Is Associated With Sarcoidosis. 2024, a2530-a2530. DOI: 10.1164/ajrccm-conference.2024.209.1_meetingabstracts.a2530.
• Macrophage Migration Inhibitory Factor (MIF) and D-Dopachrome Tautomerase (DDT): Pathways to Tumorigenesis and Therapeutic OpportunitiesValdez C, Sánchez-Zuno G, Bucala R, Tran T. Macrophage Migration Inhibitory Factor (MIF) and D-Dopachrome Tautomerase (DDT): Pathways to Tumorigenesis and Therapeutic Opportunities. International Journal Of Molecular Sciences 2024, 25: 4849. PMID: 38732068, PMCID: PMC11084905, DOI: 10.3390/ijms25094849.
• New insights into macrophage polarization and its prognostic role in patients with colorectal cancer liver metastasisKhanduri I, Maki H, Verma A, Katkhuda R, Anandappa G, Pandurengan R, Zhang S, Mejia A, Tong Z, Solis Soto L, Jadhav A, Wistuba I, Menter D, Kopetz S, Parra E, Vauthey J, Maru D. New insights into macrophage polarization and its prognostic role in patients with colorectal cancer liver metastasis. BJC Reports 2024, 2: 37. DOI: 10.1038/s44276-024-00056-8.
• Up-regulated PLA2G10 in cancer impairs T cell infiltration to dampen immunityZhang T, Yu W, Cheng X, Yeung J, Ahumada V, Norris P, Pearson M, Yang X, van Deursen W, Halcovich C, Nassar A, Vesely M, Zhang Y, Zhang J, Ji L, Flies D, Liu L, Langermann S, LaRochelle W, Humphrey R, Zhao D, Zhang Q, Zhang J, Gu R, Schalper K, Sanmamed M, Chen L. Up-regulated PLA2G10 in cancer impairs T cell infiltration to dampen immunity. Science Immunology 2024, 9: eadh2334. PMID: 38669316, DOI: 10.1126/sciimmunol.adh2334.
• Fatty acid binding protein 5 suppression attenuates obesity-induced hepatocellular carcinoma by promoting ferroptosis and intratumoral immune rewiringSun J, Esplugues E, Bort A, Cardelo M, Ruz-Maldonado I, Fernández-Tussy P, Wong C, Wang H, Ojima I, Kaczocha M, Perry R, Suárez Y, Fernández-Hernando C. Fatty acid binding protein 5 suppression attenuates obesity-induced hepatocellular carcinoma by promoting ferroptosis and intratumoral immune rewiring. Nature Metabolism 2024, 6: 741-763. PMID: 38664583, DOI: 10.1038/s42255-024-01019-6.
• Cardiovascular Outcomes of KCNJ5 mutated Aldosterone-Producing Adenoma: A Systematic Review.Kato H, Kitamoto T, Kimura S, Sunouchi T, Hoshino Y, Hidaka N, Tsurutani Y, Ito N, Makita N, Nishikawa T, Nangaku M, Inoue K. Cardiovascular Outcomes of KCNJ5 mutated Aldosterone-Producing Adenoma: A Systematic Review. Endocr Pract 2024 PMID: 38657793, DOI: 10.1016/j.eprac.2024.04.007.
• 08. Proteomic Profiling of Tumor Microenvironment In Desmoplastic Melanoma Using The Nanostring Geomx Digital Spatial ProfilerSu D, Galan A, Schoenfeld D, Ibrahim W, Cabrejo R, Baumann R, Rimm D, Khan S, Kluger H, Olino K, Clune J. 08. Proteomic Profiling of Tumor Microenvironment In Desmoplastic Melanoma Using The Nanostring Geomx Digital Spatial Profiler. Plastic & Reconstructive Surgery Global Open 2024, 12: 6-6. PMCID: PMC11041221, DOI: 10.1097/01.gox.0001015124.74133.52.
• MIF-Modulated Spinal Proteins Associated with Persistent Bladder Pain: A Proteomics StudyYe S, Agalave N, Ma F, Mahmood D, Al-Grety A, Khoonsari P, Leng L, Svensson C, Bucala R, Kultima K, Vera P. MIF-Modulated Spinal Proteins Associated with Persistent Bladder Pain: A Proteomics Study. International Journal Of Molecular Sciences 2024, 25: 4484. PMID: 38674069, PMCID: PMC11050327, DOI: 10.3390/ijms25084484.
• IL-1 receptor 1 signaling shapes the development of viral antigen-specific CD4+ T cell responses following COVID-19 mRNA vaccinationPark H, Shin M, Shin J, Kim H, Kang B, Par-Young J, Unlu S, Afinogenova Y, Catanzaro J, Young J, Kim M, Lee S, Jeon S, You S, Racke M, Bucala R, Kang I. IL-1 receptor 1 signaling shapes the development of viral antigen-specific CD4+ T cell responses following COVID-19 mRNA vaccination. EBioMedicine 2024, 103: 105114. PMID: 38640835, PMCID: PMC11041015, DOI: 10.1016/j.ebiom.2024.105114.
• Vascular mimicry as a facilitator of melanoma brain metastasisProvance O, Oria V, Tran T, Caulfield J, Zito C, Aguirre-Ducler A, Schalper K, Kluger H, Jilaveanu L. Vascular mimicry as a facilitator of melanoma brain metastasis. Cellular And Molecular Life Sciences 2024, 81: 188. PMID: 38635031, PMCID: PMC11026261, DOI: 10.1007/s00018-024-05217-z.
• Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosisGhouse J, Sveinbjörnsson G, Vujkovic M, Seidelin A, Gellert-Kristensen H, Ahlberg G, Tragante V, Rand S, Brancale J, Vilarinho S, Lundegaard P, Sørensen E, Erikstrup C, Bruun M, Jensen B, Brunak S, Banasik K, Ullum H, Verweij N, Lotta L, Baras A, Mirshahi T, Carey D, Kaplan D, Lynch J, Morgan T, Schwantes-An T, Dochtermann D, Pyarajan S, Tsao P, Laisk T, Mägi R, Kozlitina J, Tybjærg-Hansen A, Jones D, Knowlton K, Nadauld L, Ferkingstad E, Björnsson E, Ulfarsson M, Sturluson Á, Sulem P, Pedersen O, Ostrowski S, Gudbjartsson D, Stefansson K, Olesen M, Chang K, Holm H, Bundgaard H, Stender S. Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis. Nature Genetics 2024, 56: 827-837. PMID: 38632349, PMCID: PMC11096111, DOI: 10.1038/s41588-024-01720-y.
• Babesia duncani, A Model Organism for Investigating Intraerythrocytic Parasitism and Novel Anti-Parasitic Therapeutic StrategiesFang T, Mamoun C. Babesia duncani, A Model Organism for Investigating Intraerythrocytic Parasitism and Novel Anti-Parasitic Therapeutic Strategies. The Journal Of Infectious Diseases 2024, jiae191. PMID: 38626187, DOI: 10.1093/infdis/jiae191.
• Characterizing interstitial lung disease among patients with psoriasis: A cross-sectional analysis in the NIH All of Us Research ProgramShaw V, Damsky W, Homer R, Cohen J. Characterizing interstitial lung disease among patients with psoriasis: A cross-sectional analysis in the NIH All of Us Research Program. Clinical And Experimental Dermatology 2024, llae132. PMID: 38618708, DOI: 10.1093/ced/llae132.
• VHL loss reprograms the immune landscape to promote an inflammatory myeloid microenvironment in renal tumorigenesisWolf M, Madden M, Arner E, Bader J, Ye X, Vlach L, Tigue M, Landis M, Jonker P, Hatem Z, Steiner K, Gaines D, Reinfeld B, Hathaway E, Xin F, Tantawy M, Haake S, Jonasch E, Muir A, Weiss V, Beckermann K, Rathmell W, Rathmell J. VHL loss reprograms the immune landscape to promote an inflammatory myeloid microenvironment in renal tumorigenesis. Journal Of Clinical Investigation 2024, 134: e173934. PMID: 38618956, PMCID: PMC11014672, DOI: 10.1172/jci173934.
• Hyperbolic Diffusion Procrustes Analysis for Intrinsic Representation of Hierarchical Data SetsLin Y, Kluger Y, Talmon R. Hyperbolic Diffusion Procrustes Analysis for Intrinsic Representation of Hierarchical Data Sets. 2024, 6325-6329. DOI: 10.1109/icassp48485.2024.10446370.
• A supervised Bayesian factor model for the identification of multi-omics signaturesGygi J, Konstorum A, Pawar S, Aron E, Kleinstein S, Guan L. A supervised Bayesian factor model for the identification of multi-omics signatures. Bioinformatics 2024, 40: btae202. PMID: 38603606, PMCID: PMC11078774, DOI: 10.1093/bioinformatics/btae202.
• The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexiaLiu M, Ren Y, Zhou Z, Yang J, Shi X, Cai Y, Arreola A, Luo W, Fung K, Xu C, Nipp R, Bronze M, Zheng L, Li Y, Houchen C, Zhang Y, Li M. The crosstalk between macrophages and cancer cells potentiates pancreatic cancer cachexia. Cancer Cell 2024, 42: 885-903.e4. PMID: 38608702, PMCID: PMC11162958, DOI: 10.1016/j.ccell.2024.03.009.
• Guselkumab for Pityriasis Rubra Pilaris and Dysregulation of IL-23/IL-17 and NFkB SignalingVelasco R, Shao C, Cutler B, Strunck J, Kent G, Cassidy P, Choate K, Greiling T. Guselkumab for Pityriasis Rubra Pilaris and Dysregulation of IL-23/IL-17 and NFkB Signaling. JAMA Dermatology 2024, 160 PMID: 38598229, PMCID: PMC11007649, DOI: 10.1001/jamadermatol.2024.0257.
• Paradoxical PsoriasisAbdelghaffar M, Kottilil S, Murphy M, Cohen J, Damsky W. Paradoxical Psoriasis. Dermatologic Clinics 2024, 42: 471-480. PMID: 38796276, DOI: 10.1016/j.det.2024.02.011.
• Randomized Phase II Trial of Imiquimod with or without 9-Valent HPV Vaccine versus Observation in Patients with High-grade Pre-neoplastic Cervical Lesions (NCT02864147)Sheth S, Oh J, Bellone S, Siegel E, Greenman M, Mutlu L, McNamara B, Pathy S, Clark M, Azodi M, Altwerger G, Andikyan V, Huang G, Ratner E, Kim D, Iwasaki A, Levi A, Buza N, Hui P, Flaherty S, Schwartz P, Santin A. Randomized Phase II Trial of Imiquimod with or without 9-Valent HPV Vaccine versus Observation in Patients with High-grade Pre-neoplastic Cervical Lesions (NCT02864147). Clinical Cancer Research 2024, 30: of1-of10. PMID: 38592381, DOI: 10.1158/1078-0432.ccr-23-3639.
• Treatment of prolonged drug reaction with eosinophilia and systemic symptoms syndrome with dupilumab using a molecularly-guided approachValido K, Patel V, Murphy M, Junejo M, Patel D, Deutsch A, Turner N, Zaki T, King B, Damsky W, Nelson C. Treatment of prolonged drug reaction with eosinophilia and systemic symptoms syndrome with dupilumab using a molecularly-guided approach. JAAD Case Reports 2024, 48: 49-53. PMID: 38774671, PMCID: PMC11107093, DOI: 10.1016/j.jdcr.2024.03.020.
• HIV-1–infected T cell clones are shared across cerebrospinal fluid and blood during ARTWang M, Yoon J, Reisert H, Das B, Orlinick B, Chiarella J, Halvas E, Mellors J, Pang A, Barakat L, Fikrig M, Cyktor J, Kluger Y, Spudich S, Corley M, Farhadian S. HIV-1–infected T cell clones are shared across cerebrospinal fluid and blood during ART. JCI Insight 2024, 9: e176208. PMID: 38587074, PMCID: PMC11128194, DOI: 10.1172/jci.insight.176208.
• miR-1246 promotes osteosarcoma cell migration via NamiRNA-enhancer network dependent on Argonaute 2.Yang S, Zou Q, Liang Y, Zhang D, Peng L, Li W, Li W, Liu M, Tong Y, Chen L, Xu P, Yang Z, Zhou K, Xiao J, Wang H, Yu W. miR-1246 promotes osteosarcoma cell migration via NamiRNA-enhancer network dependent on Argonaute 2. MedComm (2020) 2024, 5: e543. PMID: 38585233, DOI: 10.1002/mco2.543.
• Cognitive Bias in the Patient Encounter: Part II. Debiasing using an adaptive toolboxKo C, Gehlhausen J, Cohen J, Jiang Y, Myung P, Croskerry P. Cognitive Bias in the Patient Encounter: Part II. Debiasing using an adaptive toolbox. Journal Of The American Academy Of Dermatology 2024 PMID: 38588820, DOI: 10.1016/j.jaad.2024.02.061.
• Cognitive Bias in the Patient Encounter: Part I. Background and significanceKo C, Gehlhausen J, Cohen J, Croskerry P. Cognitive Bias in the Patient Encounter: Part I. Background and significance. Journal Of The American Academy Of Dermatology 2024 PMID: 38588821, DOI: 10.1016/j.jaad.2024.01.091.
• Gene trajectory inference for single-cell data by optimal transport metricsQu R, Cheng X, Sefik E, Stanley III J, Landa B, Strino F, Platt S, Garritano J, Odell I, Coifman R, Flavell R, Myung P, Kluger Y. Gene trajectory inference for single-cell data by optimal transport metrics. Nature Biotechnology 2024, 1-11. PMID: 38580861, DOI: 10.1038/s41587-024-02186-3.
• Spiny Keratoderma: Clinical and Histopathological Findings in a Series of 3 CasesHanly A, Turner N, Ko C, Panse G. Spiny Keratoderma: Clinical and Histopathological Findings in a Series of 3 Cases. American Journal Of Dermatopathology 2024, 46: 439-442. PMID: 38574081, DOI: 10.1097/dad.0000000000002705.
• Properties and predicted functions of large genes and proteins of apicomplexan parasitesFang T, Mohseni A, Lonardi S, Mamoun C. Properties and predicted functions of large genes and proteins of apicomplexan parasites. NAR Genomics And Bioinformatics 2024, 6: lqae032. PMID: 38584870, PMCID: PMC10993292, DOI: 10.1093/nargab/lqae032.
• “Rounding Third Base and Heading Home”: Arthritis & Rheumatology in 2024Solomon D, Kaplan M, Nigrovic P, Bucala R. “Rounding Third Base and Heading Home”: Arthritis & Rheumatology in 2024. Arthritis & Rheumatology 2024, 76: 819-822. PMID: 38572586, DOI: 10.1002/art.42828.
• Impact of renal cell carcinoma molecular subtypes on immunotherapy and targeted therapy outcomesSaliby R, Labaki C, Jammihal T, Xie W, Sun M, Shah V, Saad E, Kane M, Kashima S, Sadak K, El Zarif T, Poduval D, Motzer R, Powles T, Rini B, Albiges L, Pal S, McGregor B, McKay R, Signoretti S, Van Allen E, Shukla S, Choueiri T, Braun D. Impact of renal cell carcinoma molecular subtypes on immunotherapy and targeted therapy outcomes. Cancer Cell 2024, 42: 732-735. PMID: 38579722, PMCID: PMC11130783, DOI: 10.1016/j.ccell.2024.03.002.
• Altered cerebral white matter network topology and cognition in children with obstructive sleep apneaChen F, Fu Y, Tang B, Tao B, Wang Y, Huang Y, Chen T, Yu C, Jiang C, Lui S, Cai X, Lu Y, Yan Z. Altered cerebral white matter network topology and cognition in children with obstructive sleep apnea. Sleep Medicine 2024, 118: 63-70. PMID: 38613858, DOI: 10.1016/j.sleep.2024.03.038.
• Effectiveness of Two New Endochin-like Quinolones, ELQ-596 and ELQ-650, in Experimental Mouse Models of Human BabesiosisVydyam P, Chand M, Pou S, Winter R, Liebman K, Nilsen A, Doggett J, Riscoe M, Mamoun C. Effectiveness of Two New Endochin-like Quinolones, ELQ-596 and ELQ-650, in Experimental Mouse Models of Human Babesiosis. ACS Infectious Diseases 2024, 10: 1405-1413. PMID: 38563132, PMCID: PMC11127568, DOI: 10.1021/acsinfecdis.4c00143.
• Dupilumab-associated head and neck dermatitis shows a pronounced type 22 immune signature mediated by oligoclonally expanded T cellsBangert C, Alkon N, Chennareddy S, Arnoldner T, Levine J, Pilz M, Medjimorec M, Ruggiero J, Cohenour E, Jonak C, Damsky W, Griss J, Brunner P. Dupilumab-associated head and neck dermatitis shows a pronounced type 22 immune signature mediated by oligoclonally expanded T cells. Nature Communications 2024, 15: 2839. PMID: 38565563, PMCID: PMC10987549, DOI: 10.1038/s41467-024-46540-0.
• Heterozygous CDKN2A Loss is Associated with Recurrence and Survival in High, But Not Low Grade MeningiomasTabor J, O'Brien J, Valero S, Pappajohn A, McGuone D, Erson-Omay Z, Yasuno K, Gunel M, Moliterno J. Heterozygous CDKN2A Loss is Associated with Recurrence and Survival in High, But Not Low Grade Meningiomas. Neurosurgery 2024, 70: 203-203. DOI: 10.1227/neu.0000000000002810_112.
• CLONAL HEMATOPOIESIS OF INDETERMINATE POTENTIAL (CHIP) IS AN INDEPENDENT RISK FACTOR FOR IMMUNE CHECKPOINT INHIBITOR MYOCARDITISChen N, Martinez C, Jayakrishnan R, Jiang M, Guajardo A, Vanoudenhove J, Im Y, Hwa J, Halene S, Kwan J. CLONAL HEMATOPOIESIS OF INDETERMINATE POTENTIAL (CHIP) IS AN INDEPENDENT RISK FACTOR FOR IMMUNE CHECKPOINT INHIBITOR MYOCARDITIS. Journal Of The American College Of Cardiology 2024, 83: 2492. DOI: 10.1016/s0735-1097(24)04482-6.
• Inferring B Cell Phylogenies from Paired H and L Chain BCR Sequences with Dowser.Jensen C, Sumner J, Kleinstein S, Hoehn K. Inferring B Cell Phylogenies from Paired H and L Chain BCR Sequences with Dowser. The Journal Of Immunology 2024, 212: 1579-1588. PMID: 38557795, PMCID: PMC11073909, DOI: 10.4049/jimmunol.2300851.
• Genetics of liver disease in adultsKonkwo C, Chowdhury S, Vilarinho S. Genetics of liver disease in adults. Hepatology Communications 2024, 8: e0408. PMID: 38551385, PMCID: PMC10984672, DOI: 10.1097/hc9.0000000000000408.
• Photosensitive Nanoprobes for Rapid High Purity Isolation and Size‐Specific Enrichment of Synthetic and Extracellular Vesicle SubpopulationsWeerakkody J, Tseng T, Topper M, Thoduvayil S, Radhakrishnan A, Pincet F, Kyriakides T, Gunasekara R, Ramakrishnan S. Photosensitive Nanoprobes for Rapid High Purity Isolation and Size‐Specific Enrichment of Synthetic and Extracellular Vesicle Subpopulations. Advanced Functional Materials 2024 DOI: 10.1002/adfm.202400390.
• An algorithm for standardization of tumor Infiltrating lymphocyte evaluation in head and neck cancersXirou V, Moutafi M, Bai Y, Nwe Aung T, Burela S, Liu M, Kimple R, Shabbir Ahmed F, Schultz B, Flieder D, Connolly D, Psyrri A, Burtness B, Rimm D. An algorithm for standardization of tumor Infiltrating lymphocyte evaluation in head and neck cancers. Oral Oncology 2024, 152: 106750. PMID: 38547779, PMCID: PMC11060915, DOI: 10.1016/j.oraloncology.2024.106750.
• Retinal Ischemic Perivascular Lesions Are Associated With Myocardial Infarction in Patients With Coronary Artery DiseaseBousquet E, Santina A, Au A, Somisetty S, Abraham N, Voichanski S, Estawro R, Fouad Y, Romero-Morales V, Bakhoum M, Sarraf D. Retinal Ischemic Perivascular Lesions Are Associated With Myocardial Infarction in Patients With Coronary Artery Disease. American Journal Of Ophthalmology 2024, 264: 224-228. PMID: 38552932, DOI: 10.1016/j.ajo.2024.03.017.
• TGF-β1 Drives Integrin-Dependent Pericyte Migration and Microvascular Destabilization in Fibrotic DiseasePellowe A, Wu M, Kang T, Chung T, Ledesma-Mendoza A, Herzog E, Levchenko A, Odell I, Varga J, Gonzalez A. TGF-β1 Drives Integrin-Dependent Pericyte Migration and Microvascular Destabilization in Fibrotic Disease. American Journal Of Pathology 2024, 194: 1171-1184. PMID: 38548268, DOI: 10.1016/j.ajpath.2024.02.021.
• Tumor Necrosis Factor Receptor-2 Signals Clear-Cell Renal Carcinoma Proliferation via Phosphorylated 4E Binding Protein-1 and Mitochondrial Gene TranslationAl-Lamki R, Tolkovsky A, Alawwami M, Lu W, Field S, Wang J, Pober J, Bradley J. Tumor Necrosis Factor Receptor-2 Signals Clear-Cell Renal Carcinoma Proliferation via Phosphorylated 4E Binding Protein-1 and Mitochondrial Gene Translation. American Journal Of Pathology 2024, 194: 1374-1387. PMID: 38537932, DOI: 10.1016/j.ajpath.2024.02.019.
• Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscapeBoddu P, Gupta A, Roy R, De La Peña Avalos B, Olazabal-Herrero A, Neuenkirchen N, Zimmer J, Chandhok N, King D, Nannya Y, Ogawa S, Lin H, Simon M, Dray E, Kupfer G, Verma A, Neugebauer K, Pillai M. Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape. Molecular Cell 2024, 84: 1475-1495.e18. PMID: 38521065, PMCID: PMC11061666, DOI: 10.1016/j.molcel.2024.02.032.
• Variations in the genomic profiles and clinical behavior of meningioma by racial and ethnic group.Tabor J, Dincer A, O'Brien J, Lei H, Vetsa S, Vasandani S, Jalal M, Yalcin K, Morales-Valero S, Marianayagam N, Alanya H, Elsamadicy A, Millares Chavez M, Aguilera S, Mishra-Gorur K, McGuone D, Fulbright R, Jin L, Erson-Omay E, Günel M, Moliterno J. Variations in the genomic profiles and clinical behavior of meningioma by racial and ethnic group. Journal Of Neurosurgery 2024, 1-9. PMID: 38518289, DOI: 10.3171/2024.1.jns231633.
• Abstract 1718: The lysine demethylase KDM2A regulates tumor cell clustering to potentiate metastasisKravitz C, Patel K, Cai W, Arnal-Estapé A, Zhao D, Wingrove E, Stevens L, Westbrook T, Yan Q, Nguyen D. Abstract 1718: The lysine demethylase KDM2A regulates tumor cell clustering to potentiate metastasis. Cancer Research 2024, 84: 1718-1718. DOI: 10.1158/1538-7445.am2024-1718.
• Humanin variant P3S is associated with longevity in APOE4 carriers and resists APOE4‐induced brain pathologyMiller B, Kim S, Cao K, Mehta H, Thumaty N, Kumagai H, Iida T, McGill C, Pike C, Nurmakova K, Levine Z, Sullivan P, Yen K, Ertekin‐Taner N, Atzmon G, Barzilai N, Cohen P. Humanin variant P3S is associated with longevity in APOE4 carriers and resists APOE4‐induced brain pathology. Aging Cell 2024, e14153. PMID: 38520065, DOI: 10.1111/acel.14153.
• Abstract 4104: Randomized phase II trial of imiquimod with or without 9vHPV vs observation in patients with CIN 2 and 3Sheth S, Oh J, Bellone S, Siegel E, Buza N, Iwasaki A, Santin A. Abstract 4104: Randomized phase II trial of imiquimod with or without 9vHPV vs observation in patients with CIN 2 and 3. Cancer Research 2024, 84: 4104-4104. DOI: 10.1158/1538-7445.am2024-4104.
• Abstract 3086: NAPRT silencing in oncometabolite-producing cancers confers therapeutic vulnerabilities to NAD+ depletionNoronha K, Lucas K, Zhao S, Edmonds J, Friedman S, Murray M, Liu S, Liang J, Paradkar S, Zeng H, Sundaram R, Spurrier J, Raponi M, Sajed D, Shuch B, Vasquez J, Bindra R. Abstract 3086: NAPRT silencing in oncometabolite-producing cancers confers therapeutic vulnerabilities to NAD+ depletion. Cancer Research 2024, 84: 3086-3086. DOI: 10.1158/1538-7445.am2024-3086.
• Abstract 3632: Cytokine profiles associated with ICI myocarditis using machine learning approaches identifies novel cytokines and implicated pathwaysChehayeb R, Hong D, Chen N, Martinez C, Jayakrishnan R, Guajardo A, Lin D, Im Y, Halene S, VanOudenhove J, Hwa J, Jha A, Kwan J. Abstract 3632: Cytokine profiles associated with ICI myocarditis using machine learning approaches identifies novel cytokines and implicated pathways. Cancer Research 2024, 84: 3632-3632. DOI: 10.1158/1538-7445.am2024-3632.
• Abstract 7123: Biomarker-targeted alkylator and DNA damage repair inhibitor combination for refractory and relapsed acute myeloid leukemia (AML)Bhardwaj P, Sundaram R, Baassiri A, Matthews M, VanOudenhove J, Gueble S, Halene S, Bindra R. Abstract 7123: Biomarker-targeted alkylator and DNA damage repair inhibitor combination for refractory and relapsed acute myeloid leukemia (AML). Cancer Research 2024, 84: 7123-7123. DOI: 10.1158/1538-7445.am2024-7123.
• Abstract 4293: Chromosomal instability causes epigenetic aberrations in cancerAgustinus A, Al-Rawi D, Dameracharla B, Raviram R, Jones B, Stransky S, Scipioni L, Luebeck J, Bona M, Norkunaite D, Myers R, Duran M, Choi S, Weigelt B, Yomtoubian S, McPherson A, Toufektchan E, Keuper K, Mischel P, Mittal V, Shah S, Maciejowski J, Storchova Z, Gratton E, Ly P, Landau D, Bakhoum M, Koche R, Sidoli S, Bafna V, David Y, Bakhoum S. Abstract 4293: Chromosomal instability causes epigenetic aberrations in cancer. Cancer Research 2024, 84: 4293-4293. DOI: 10.1158/1538-7445.am2024-4293.
• Abstract 7117: Convection enhanced delivery of a novel ATR inhibitor synergizes with systemic lomustine for improved treatment of glioblastomaJosowitz A, Lee T, Sundaram R, Pothupitiya J, Brown E, Sule A, Beckta J, Wang Y, Vacca J, Gilad O, Bindra R, Saltzman W. Abstract 7117: Convection enhanced delivery of a novel ATR inhibitor synergizes with systemic lomustine for improved treatment of glioblastoma. Cancer Research 2024, 84: 7117-7117. DOI: 10.1158/1538-7445.am2024-7117.
• Abstract 101: A novel humanized mouse model recapitulates the unique TME found in patients with HIV-associated NSCLCJuric M, Kaufmann G, Zhu L, Ranjan K, Agrawal K, Rajendran B, Rajashekar J, Zhao H, Kluger Y, Emu B, Schalper K, Kumar P, Flavell R, Chiorazzi M. Abstract 101: A novel humanized mouse model recapitulates the unique TME found in patients with HIV-associated NSCLC. Cancer Research 2024, 84: 101-101. DOI: 10.1158/1538-7445.am2024-101.
• Abstract 2866: NAPRT silencing in rhabdomyosarcoma confers therapeutic vulnerabilities to NAD+depletionZhao S, Noronha K, Bhardwaj P, Lucas K, Sundaram R, Heer C, Morotti R, Spurrier J, Raponi M, Bindra R, Vasquez J. Abstract 2866: NAPRT silencing in rhabdomyosarcoma confers therapeutic vulnerabilities to NAD+depletion. Cancer Research 2024, 84: 2866-2866. DOI: 10.1158/1538-7445.am2024-2866.
• Abstract 1058: Immune biomarkers for recurrence in stage II and III melanoma to guide patient stratificationEspinoza G, Zhang C, Moon J, Kenchappa D, Abbruzzese M, Bioh L, Bracero Y, Sultana S, Singh A, Aung T, Krolewski J, Gartrell R, Geskin L, Leung L, Ferringer T, Chang R, Horst B, Nastiuk K, Saenger Y. Abstract 1058: Immune biomarkers for recurrence in stage II and III melanoma to guide patient stratification. Cancer Research 2024, 84: 1058-1058. DOI: 10.1158/1538-7445.am2024-1058.
• Abstract 6732: Immunomodulatory and anti-tumor effect of a CCR2-targeted STING agonist iADC in human lung cancerPorciuncula A, Appleman V, Parent A, Raizer J, Gregory R, Lineberry N, Abu-Yousif A, Schalper K. Abstract 6732: Immunomodulatory and anti-tumor effect of a CCR2-targeted STING agonist iADC in human lung cancer. Cancer Research 2024, 84: 6732-6732. DOI: 10.1158/1538-7445.am2024-6732.