3D Orthopaedics Lab
We are a discovery-driven research group working at the interface of orthopaedics, engineering, and personalized medicine. Our focus is on leveraging 3D technologies to advance treatments for musculoskeletal conditions, such as avascular necrosis, orthopaedic trauma, patellofemoral and upper extremity biomechanics and rehabilitation engineering. We combine cutting-edge imaging, surgical simulations, and computational modeling to design patient-specific instruments and techniques, aiming to optimize precision and improve outcomes in orthopaedic care. Ultimately, our work seeks to provide surgeons with innovative solutions tailored to the unique anatomical and clinical needs of each patient.
Research Areas
Our Team
Affiliate Organizations/Programs
- 3D Collaborative for Medical Innovation (3DC) The 3D Collaborative for Medical Innovation (3DC) at Yale supports researchers with specialized engineering and 3D printing services, particularly for medical imaging-based projects. Their offerings include digital model segmentation, anatomical model creation and modification, CAD for medical devices, and more.
- Yale Orthopaedics Biomechanics Laboratory The Yale Orthopaedics Biomechanics Laboratory is renowned for work delineating clinically relevant aspects of musculoskeletal injury. The Biomechanics Lab assesses the biomechanical properties of musculoskeletal tissues by providing services and technical assistance in a variety of biomechanical testing techniques.
- MS in Personalized Medicine and Applied Engineering The MS degree in Personalized Medicine & Applied Engineering provides medical students, biomedical, mechanical, and electrical engineers, and computer science majors with the tools to develop innovative 3D solutions for personalized medicine.
Selected Publications
2024
Analyzing Alignment Error in Tibial Tuberosity–Trochlear Groove Distance in Clinical Scans Using 2D and 3D Methods
Sieberer J, Park N, Rancu A, Desroches S, McDonald C, Manafzadeh A, Tommasini S, Wiznia D, Fulkerson J. Analyzing Alignment Error in Tibial Tuberosity–Trochlear Groove Distance in Clinical Scans Using 2D and 3D Methods. The American Journal Of Sports Medicine 2024, 52: 2996-3003. PMID: 39320426, DOI: 10.1177/03635465241279852.Peer-Reviewed Original ResearchCitationsAltmetricConceptsTibial tuberosity-trochlear groove distanceSurgical decision-makingPatellofemoral instabilityIntraclass correlation coefficientGroove distanceTreatment of patellofemoral instabilityComputed tomography scanTT-TG distanceScans of patientsPatient's legsTT-TG measurementsTibial tubercle transferKnees of patientsInterrater reliabilityGt;5 mmTomography scanSurgical planningTubercle transferScanner gantryPatientsClinical scansClinical literatureTopographic landmarksKneeDecision-makingFabricating patient-specific 3D printed drill guides to treat femoral head avascular necrosis
Bell C, Feizi A, Roytman G, Ramji A, Tommasini S, Wiznia D. Fabricating patient-specific 3D printed drill guides to treat femoral head avascular necrosis. 3D Printing In Medicine 2024, 10: 10. PMID: 38564090, PMCID: PMC10986134, DOI: 10.1186/s41205-024-00208-z.Peer-Reviewed Original ResearchCitationsConceptsUsing Computed Tomography-Based Three-dimensional Modeling and Computer Navigation for Minimally Invasive Core Decompression and Adjuvant Orthobiologic Therapy of Femoral Head Avascular Necrosis
Feizi A, Bell C, Roytman G, Park N, Wang A, Tommasini S, Wiznia D. Using Computed Tomography-Based Three-dimensional Modeling and Computer Navigation for Minimally Invasive Core Decompression and Adjuvant Orthobiologic Therapy of Femoral Head Avascular Necrosis. Arthroplasty Today 2024, 26: 101337. PMID: 38497084, PMCID: PMC10940782, DOI: 10.1016/j.artd.2024.101337.Peer-Reviewed Original ResearchCitationsAltmetricConceptsFemoral head avascular necrosisAvascular necrosisSurgical techniqueCore decompressionBone marrow aspirate concentrateDelay disease progressionOutcome of core decompressionAdjuvant therapyCellular therapyAspirate concentrateDisease progressionFemoral head collapseImprove outcomesLesionsDebilitating conditionTherapyComputer navigationNecrosisDecompressionHead collapseThree-dimensional modelFemoral headThe feasibility of a novel 3D-Printed patient specific cutting guide for extended trochanteric osteotomies
Bergemann R, Roytman G, Ani L, Ramji A, Leslie M, Tommasini S, Wiznia D. The feasibility of a novel 3D-Printed patient specific cutting guide for extended trochanteric osteotomies. 3D Printing In Medicine 2024, 10: 7. PMID: 38427157, PMCID: PMC10905807, DOI: 10.1186/s41205-024-00204-3.Peer-Reviewed Original ResearchCitationsConceptsPatient-specific cutting guidesCutting guidesPlanned osteotomySoft tissue injuriesTotal hip arthroplasty surgeryCT scanSurgical techniqueRevision total hip arthroplasty surgeryClinical trialsPerformed osteotomyHip arthroplasty surgeryTissue injuryNon-unionPatientsCadaveric testingSimpleware ScanIPOsteotomySoft tissueTrochanteric osteotomyProximal femurArthroplasty surgeryIntramedullary canalHuman subjectsExtended trochanteric osteotomyFemoral canal
2023
An analytical model of lateral condylar plate working length
Roytman G, Beitler B, LaMonica J, Spero M, Toy K, Ramji A, Yoo B, Leslie M, Baumgaertner M, Tommasini S, Wiznia D. An analytical model of lateral condylar plate working length. Clinical Biomechanics 2023, 110: 106129. PMID: 37871506, PMCID: PMC10848195, DOI: 10.1016/j.clinbiomech.2023.106129.Peer-Reviewed Original ResearchMeSH Keywords and ConceptsThree-Dimensional Printing of Models of Patellofemoral Joint Articular Cartilage in Patients With Patella Instability for Observing Joint Congruity
Beitler B, Kunsel K, Yu K, Wang A, Tommasini S, Wiznia D, Fulkerson J. Three-Dimensional Printing of Models of Patellofemoral Joint Articular Cartilage in Patients With Patella Instability for Observing Joint Congruity. Arthroscopy Techniques 2023, 12: e1853-e1858. PMID: 37942111, PMCID: PMC10628265, DOI: 10.1016/j.eats.2023.06.016.Peer-Reviewed Original ResearchCitationsAltmetricSimulating movements of daily living in robot-assisted total hip arthroplasty with 3D modelling
Tung W, Donnelley C, Pour A, Tommasini S, Wiznia D. Simulating movements of daily living in robot-assisted total hip arthroplasty with 3D modelling. Bone & Joint Open 2023, 4: 416-423. PMID: 37263587, PMCID: PMC10234721, DOI: 10.1302/2633-1462.46.bjo-2023-0046.r1.Peer-Reviewed Original ResearchCitationsAltmetricConceptsTotal hip arthroplastyPreoperative protocolHip arthroplastyExternal rotationPrimary total hip arthroplastyRobot-assisted total hip arthroplastyPatient's preoperative imagingRisk of impingementPreoperative planning softwareHip abduction/adductionPreoperative imagingMost hipsSacral slopePostoperative stabilityDaily livingHip flexion/extensionAbduction/adductionFlexion/extensionPlanning platformKnee positionPatient safetyPatient positionMaximum external rotationPlanning softwareHipThree-Dimensional Printing of the Patellofemoral Joints of Patellar Instability Patients
Beitler B, Yu K, Wang A, Frumberg D, Tommasini S, Wiznia D, Cooperman D, Lattanza L, Fulkerson J. Three-Dimensional Printing of the Patellofemoral Joints of Patellar Instability Patients. Arthroscopy Techniques 2023, 12: e401-e406. PMID: 37013007, PMCID: PMC10066413, DOI: 10.1016/j.eats.2022.11.023.Peer-Reviewed Original ResearchCitationsAltmetric
2022
Personalizing Revision Tibial Baseplate Position and Stem Trajectory With Custom Implants Using 3D Modeling to Optimize Press-fit Stem Placement
Cooperman C, Wiznia D, Kunsel K, Roytman G, Ani L, Pratola D, Lee GC, Tommasini S, Bernstein J. Personalizing Revision Tibial Baseplate Position and Stem Trajectory With Custom Implants Using 3D Modeling to Optimize Press-fit Stem Placement. Arthroplasty Today 2022, 18: 45-51. PMID: 36267389, PMCID: PMC9576531, DOI: 10.1016/j.artd.2022.08.011.Peer-Reviewed Original ResearchCitationsFinite Element Evaluation of the Femoral Neck System as Prophylactic Fixation to Prevent Contralateral Hip Fractures
LaMonica J, Rhee B, Milligan K, Leslie M, Tommasini S, Wiznia D. Finite Element Evaluation of the Femoral Neck System as Prophylactic Fixation to Prevent Contralateral Hip Fractures. Geriatric Orthopaedic Surgery & Rehabilitation 2022, 13: 21514593221135117. PMID: 36393901, PMCID: PMC9661561, DOI: 10.1177/21514593221135117.Peer-Reviewed Original ResearchAltmetricConceptsFinite element analysisFemoral neck systemContralateral hip fractureElement analysisHip fractureBone failurePeak stressProximal femurTrabecular bone failureFinite element evaluationCortical bone failureVon Mises stressContralateral proximal femurPrimary hip fractureNeck systemOsteoporotic proximal femurCadaveric biomechanical studyPharmacologic treatmentElement evaluationGeriatric patientsSignificant morbidityProphylactic fixationFemoral neckFall preventionBone qualityAccuracy of guide wire placement for femoral neck stabilization using 3D printed drill guides
Roytman GR, Ramji AF, Beitler B, Yoo B, Leslie MP, Baumgaertner M, Tommasini S, Wiznia DH. Accuracy of guide wire placement for femoral neck stabilization using 3D printed drill guides. 3D Printing In Medicine 2022, 8: 19. PMID: 35781846, PMCID: PMC9254431, DOI: 10.1186/s41205-022-00146-8.Peer-Reviewed Original ResearchCitationsConceptsDiameter drill bitsAverage angular deviationAverage displacementLow positional accuracyImage processing techniquesIdeal implant positioningAccurate positioningDifferent implant systemsDrill guideProcessing techniquesDrill bitAngular deviationPositional accuracyWireImage processing softwareImplant systemDisplacementVirtual modelCustom 3DWire entryFemoral neckSawbonesGuide wireSawbone modelOptimal position
News
- June 12, 2025
Chief Residents Conclude Five-Year Orthopaedic Surgery Training with Disputations
- May 23, 2025
Eighteen Faculty Selected as Research All Stars by Avant-garde Health
- May 12, 2025
Inaugural Keggi Memorial Lectureship Honors the Legacy of a Pioneer
- May 09, 2025
2025 “Top Doctors” List Features 16 Orthopaedics & Rehabilitation Faculty
- October 30, 2024
Medicine and Engineering Converge Over Advanced Technology in Master’s Program
- August 07, 2024
Grant to Help Team Develop Dynamic 3D Tumor Analysis