Study Suggests Retina Represents System for Investigating Therapeutic Approaches in Neurodegenerative Diseases
The findings provide evidence that the retina, the site of damage in advanced macular degeneration—the leading cause of blindness in elderly patients—is also a source for knowledge about treating neurodegenerative diseases.
Deep Learning of the Retina Enables Phenome - and Genome-wide Analyses of the Microvasculature
The microvasculature, the smallest blood vessels in the body, has key roles in maintenance of organ health as well as tumorigenesis. The retinal fundus is a window for human in vivo non-invasive assessment of the microvasculature. Large-scale complementary machine learning-based assessment of the retinal vasculature with phenome-wide and genome-wide analyses may yield new insights into human health and disease.Source: Deep Learning of the Retina Enables Phenome - and Genome-wide Analyses of the Microvasculature
Mammals’ Enhanced Capacity to See Emerges Early in Development
All vertebrates possess a primitive network in which the retina sends signals directly to the superior colliculus, an area of the brain that processes visual stimuli. In a more recently evolved pathway, signals from the retina are received in the thalamus and are relayed to the cortex, the brain’s seat of higher-order thinking.
David W. Wallace, 1924-2017, generous and loyal benefactor
David W. Wallace, a former corporate attorney, businessman, and philanthropist who was a longtime supporter of the School of Medicine and Yale University, died at home in Greenwich, Connecticut, on Dec. 24, 2017. He was 93.Source: Medicine@Yale
Lost in translation: Parkinson’s disease research undercut by study design
In a review of animal studies of Parkinson’s disease therapies, Yale researchers identified trends that may contribute to the lack of success in human clinical trials. Their finding provides insight to investigators who seek new therapies to slow the progression of the disease.
YSPH To Host Advance Screening of Risky Drinking, Documentary on the Dangers of Alcohol Abuse
An advance screening of Risky Drinking, a soon-to-be-released documentary on the dangers of alcohol abuse, followed by a panel discussion, will be held at the Yale School of Public Health on November 17. In time to mark the annual Harvard-Yale football game that will take place at Harvard Stadium on November 19, the film will also be screened at Harvard’s T.H. Chan School of Public Health on November 16.
Yale alumna wins ‘best social impact pitch’ in first Unite For Sight innovation competition
“What Stanford is to classic tech entrepreneurship, Yale is becoming to social entrepreneurship,” Carlos Watson wrote in OZY on Jan. 2, 2014, citing alumni founders and leaders of groups ranging from the Children’s Defense Fund to the Global HealthCorps.
Genetic Underpinnings of AMD, Other Diseases Revealed in YSPH Studies
A Yale School of Public Health researcher who discovered the gene behind age-related macular degeneration (AMD) has made new discoveries that increase the understanding of the mechanisms behind AMD and other diseases, including Parkinson’s disease.